In [1]:
# =========================================
# Etape 1 : Configuration de l'environnement
# =========================================

import os
from itertools import count
from dotenv import load_dotenv
import pytesseract

load_dotenv()

# Définir les chemins dynamiquement
user_profile = os.path.expanduser("~")  # Équivaut à $env:USERPROFILE
# emplacement de l'exécutable
tesseract_path = os.path.join(user_profile, "anaconda3", "envs", "Medipy", "Library", "bin", "tesseract.exe")
# pointe vers le dossier contenant les fichiers de données de langue Tesseract
tessdata_prefix = os.path.join(user_profile, "anaconda3", "envs", "Medipy", "share", "tessdata")

# Configurer pytesseract
pytesseract.pytesseract.tesseract_cmd = tesseract_path
os.environ["TESSDATA_PREFIX"] = tessdata_prefix # env variable

# vérif
print("Tesseract cmd path:", pytesseract.pytesseract.tesseract_cmd)
print("TESSDATA_PREFIX:", os.environ["TESSDATA_PREFIX"])
In [2]:
# =========================================
# Etape 2 : Extraction de texte à partir d'un PDF
# =========================================

import requests
import pdf2image
import pytesseract

# Téléchargement du fichier PDF
pdf_url = 'https://www.mdpi.com/1422-0067/21/4/1306/pdf?version=1581850486'
response = requests.get(pdf_url)

if response.status_code == 200:
    # Conversion PDF ➡️ Images
    pages = pdf2image.convert_from_bytes(response.content)

    # Extraction de texte avec OCR (limite à 6 premières pages)
    extracted_text = []
    for page_number, page_data in enumerate(pages):
        if page_number < 6:  # Traite uniquement les 6 premières pages
            text = pytesseract.image_to_string(page_data)
            extracted_text.append(text)

    # Fusionner le texte extrait
    full_text = " ".join(extracted_text)

    # Afficher les 500 premiers caractères pour vérification
    print(full_text[:500])
else:
    print(f"Erreur lors du téléchargement du PDF : {response.status_code}")
International Journal of

ZA
Molecular Sciences (moPt)

Review

Hopes and Limits of Adipose-Derived Stem Cells
(ADSCs) and Mesenchymal Stem Cells (MSCs) in
Wound Healing

Loubna Mazini '*, Luc Rochette 2, Brahim Admou 3®, Said Amal 4 and Gabriel Malka !

1 Laboratoire Cellules Souches et Régénération Cellulaire et Tissulaire, Centre interface Applications

Médicales (CIAM), Université Mohammed VI Polytechnique, Ben-Guerir 43 150, Morocco;
gabriel.malka@um6p.ma

Equipe d’Accueil (EA 7460), Physio
In [3]:
# =========================================
# Etape 3 : Extraction d'entités biomédicales
# =========================================

import requests
from bs4 import BeautifulSoup

# URL de la page PubMed
url = "https://pubmed.ncbi.nlm.nih.gov/32075181/"
response = requests.get(url)

# Extraction HTML avec BeautifulSoup
if response.status_code == 200:
    soup = BeautifulSoup(response.content, 'html.parser')
    title = soup.find('h1', class_='heading-title').get_text(strip=True)
    authors = [author.get_text(strip=True) for author in soup.find_all('a', class_='full-name')]
    print("Titre :", title)
    print("Auteurs :", ", ".join(authors))
else:
    print(f"Erreur lors de l'accès à PubMed : {response.status_code}")
Titre : Hopes and Limits of Adipose-Derived Stem Cells (ADSCs) and Mesenchymal Stem Cells (MSCs) in Wound Healing
Auteurs : Loubna Mazini, Luc Rochette, Brahim Admou, Said Amal, Gabriel Malka, Loubna Mazini, Luc Rochette, Brahim Admou, Said Amal, Gabriel Malka
In [4]:
# =========================================
# Etape 4 : Extraction d'entités biomédicales
# =========================================

import nltk
import os
import re

# Configurer le chemin pour NLTK
nltk_data_path = os.getenv("PDF2_PATH_NLTK_DATA")
# cela enregistre le fichier sous :
os.makedirs(nltk_data_path, exist_ok=True)
nltk.data.path.append(nltk_data_path)

# Télécharger le tokenizer Punkt si nécessaire
nltk.download('punkt', download_dir=nltk_data_path)

def clean_text(text):
    """
    Supprime les sections inutiles et nettoie le texte.
    """
    # Filtrer les lignes courtes et celles qui commencent par des mots-clés inutiles
    clean = "\n".join([
        row for row in text.split("\n")
        if len(row.split(" ")) > 3 and not row.lower().startswith(("figure", "(a)"))
    ])
    return clean

def remove_headers_footers(text, patterns):
    """
    Supprime les en-têtes et pieds de page récurrents basés sur des motifs.
    """
    for pattern in patterns:
        text = re.sub(pattern, '', text)
    return text

# todo : rendre insensible à la casse le mot "1. Introduction"
def extract_relevant_text(full_text, start_keyword="1. Introduction"):
    """
    Extrait la section de texte après le mot-clé 'Introduction'.
    """
    if start_keyword.lower() in full_text.lower():
        # Découpe à partir du mot-clé "Introduction"
        relevant_text = full_text.split(start_keyword, 1)[1]
        return relevant_text
    return full_text  # Retourne tout si le mot-clé n'est pas trouvé

# motifs d'en-têtes et pieds de page récurrents (spécifiques à l'article)
header_footer_patterns = [
    r"Int\. J\. Mol\. Sci\.\s?\d{4},\s?\d{2},\s?\d+;",  # Ex. "Int. J. Mol. Sci. 2020, 21, 1306;"
    r"www\.mdpi\.com/journal/ijms",                   # Ex. "www.mdpi.com/journal/ijms"
    r"\s?Int\. J\. Mol\. Sci\. \d{4}, \d{2}, \d+ \d+ of \d+",  # Ex. "Int. J. Mol. Sci. 2020, 21, 1306 2 of 19"
]

# Appliquer les transformations sur le texte extrait
if 'full_text' in locals():
    # Extraction de la section après "Introduction"
    relevant_text = extract_relevant_text(full_text, start_keyword="Introduction")

    # Suppression des en-têtes et pieds de page
    text_without_headers = remove_headers_footers(relevant_text, header_footer_patterns)

    # Nettoyage des lignes inutiles
    cleaned_text = clean_text(text_without_headers)

    # Tokenisation en phrases
    sentences = nltk.tokenize.sent_tokenize(cleaned_text)

    # Vérifications
    print(f"Nombre de phrases extraites : {len(sentences)}")
    print("Exemple de phrases :", sentences[:3])
    print("Texte nettoyé : ", cleaned_text)
[nltk_data] Downloading package punkt to
[nltk_data]     C:\Users\jonat\Code\DataScience\MedipyJupyter\data\PDF
[nltk_data]     2...
[nltk_data]   Unzipping tokenizers\punkt.zip.
Nombre de phrases extraites : 114
Exemple de phrases : ['Multipotent mesenchymal/stromal stem cells (MSCs) have been identified as residual stem cells in\nalmost all adult organs, especially within adipose tissue (AT).', 'These cells present, in vitro, the typical\nmesenchymal cell characteristics and are isolated within the stromal vascular fraction (SVF) [1,2].', 'Mainly called adipose derived stem cells (ASCs or ADSCs) and isolated in a less invasive and more\nreproducible manner, these cells are more proliferative and have immunosuppressive properties that\nare able to inactivate T cells [3,4].']
Texte nettoyé :  Multipotent mesenchymal/stromal stem cells (MSCs) have been identified as residual stem cells in
almost all adult organs, especially within adipose tissue (AT). These cells present, in vitro, the typical
mesenchymal cell characteristics and are isolated within the stromal vascular fraction (SVF) [1,2].
Mainly called adipose derived stem cells (ASCs or ADSCs) and isolated in a less invasive and more
reproducible manner, these cells are more proliferative and have immunosuppressive properties that
are able to inactivate T cells [3,4]. ADSCs were demonstrated to differentiate into the adipogenic lineage
when compared to bone marrow (BM)- and umbilical cord (UC)-MSCs, however their multipotency is
actually more appreciated for ectodermic and endodermic tissue repair [4-6].
As evidenced by most reports, ADSCs are able to secrete a rich secretome, whereby cell proliferation
and differentiation, migration, and an improvement to the cellular and microenvironment protection
occurred [7-13]. This secretome corresponds to a panel of trophic factors, such as cytokines, growth
factors, and chemokines, which allow ADSCs to act as paracrine tools that are more likely than cell
replacement. Used as exosomes or conditioned-media, this secretome has opened the way to a newly
emerged, cell-free therapy [13,14].
Recently, ADSCs were identified within subcutaneous tissue [15]. Their presence allows us
to expect them to play a pivotal role in skin repair and regeneration. Indeed, there was evidence
for the critical role of ADSCs in maintaining the structure of skin tissue, even as a physiological
response to local injury or as rejuvenating mechanisms by seeding younger cells to the outer of the
epidermis [5,15—-17]. Identified within the basal layer where they self-renewed and differentiated to
continuously settle the epidermis with keratinocytes, fibroblasts, and melanocytes [18,19], these cells
might influence the physiological characteristics of the injured skin and presented with a great ability in
migration and were recruited into wounded sites [11,20-22]. ADSCs have been shown to differentiate
into keratinocytes, dermal fibroblasts (DF), and other skin components [15,23,24].
Additionally, ADSCs might be influenced in their ability to regenerate the injured tissue. In skin
aging, these cells are expected to reduce their proliferation while their differentiation ability remains
conserved, with a decrease of ECM secretion and an increase of cell apoptosis and accumulation
of senescent cells [25,26]. Senescent cells secrete a specific senescent secretome [27], resulting in an
increase in aging-associated cell symptoms that are morphologically apparent by the loss of skin
elasticity, thickness, and increasing wrinkles [28]. Moreover, aging also impacts other epithelial cells
that reduce their replicative capacity and induce reactive oxygen species (ROS) accumulation, as well
as decreasing DF size and function [29-31].
Finally, the changes in the cell composition of the dermis and the ability of different epithelial
cells to secrete specific growth factors such as TGF-B, GDF11, GDF15, b-FGF, VEGF, MMP-1, MMP-2,
MMP-9, and extracellular matrix (ECM) proteins confer the possibility of establishing a balance between
cell regeneration and cell rejuvenation to the ADSC’s microenvironment. In this review, we attempt to
emphasize the mutual interactions between ADSCs, their surrounding cells, ECM proteins, and the
panel of the microenvironment growth factors, as well as to determine their role in the regulation and
the induction of cell regeneration in cases of injury and aging. Controlling this microenvironment might
raise a potential to increase cell functionality and life span in order to counterbalance the physiological
symptoms related to aging-associated diseases. This might open the way to a new era of managing the
organ life span for promising therapeutic advancements.
2. The Skin between the Theory and the Physiology of Aging
Skin morphology is the illustration of observable time passing by epidermal atrophy related to
wrinkles appearance, reduction of dermal thickness, and pigmentation defects. This extrinsic aging
also reflects an intrinsic aging associated with structural and proliferative deficiencies. The decrease in
the number of epithelial cells, including DF, Langerhans cells, and melanocytes, together with ECM
degradation, results in an impairment of skin integrity and youth. Mutual interactions between DF
and epidermal cells are closely related to skin integrity and are indicators of cellular and molecular
changes during aging [32].
Epidermal cells and DF play a critical role in defining skin architecture and function. ECM proteins,
mainly produced by DF and ADSCs, are composed of glycosaminoglycans, collagen type I, type III,
and elastin, and are continuously modified by physiological and extrinsic factors. Collagen production
is also decreased simultaneously with its degradation, leading to quantitative and qualitative changes
in collagen fibers, and thus impacting the dermis structure [25,33]. Collagen I and III are degraded by
the matrix metalloprotease 1 (MMP-1), the most ubiquitous endopeptidase secreted by keratinocyte,
DE, and endothelial cells. However, the degradation of elastin fibers is the other representation of the
dermis atrophy and it is connected to photoaging and is induced by MMP-2, -3, -9, and -12 [34,35].
These MMP levels increase with age and are modulated by MMP (TIMPs) tissue inhibitors. Their ratio
is balanced during aging, in favor of MMP accelerating collagen deficiencies [36].
External physiological factors or UV are responsible for the degradation of ECM leading to an
increase in enzymatic activity associated with collagen degeneration and loss of mechanical functions
such as elasticity [37]. The skin might also be physiologically predisposed to accelerated aging and
carcinogenesis; this is the case for various genetic syndromes that favored DNA damage or telomere
dysfunction and cellular senescence. The decline in DNA repair ability, the increase of oxidative stress,
and the shortening of the telomeres, may drive cells towards senescence [38].
Other intrinsic factors are known to impair physiological functions of the skin and are associated
with cell senescence, including DNA damage [39,40], telomeres shortening [41], and reactive oxygen
species (ROS) production [42]. All these processes show major roles in inducing tissue-aging and
3. Role of the Microenvironment in ADSCs Induction
ADSCs reside in vivo within adipose tissue in a specific location called “stem cell niche” where
they are closely built-in with the ECM and the other supporting cells [45]. The relationship of ADSCs
with this surrounding microenvironment and the mechanisms of action involved still requires further
elucidation. In wound healing or aging, this microenvironment conditioned and modulated the
involvement of ADSCs in the different mechanisms associated with skin tissue repair and anti-aging.
The microenvironment may modulate the biological properties and the ability of ADSCs to
proliferate, differentiate, and migrate to restore cellular age defects and repair wound healing [46-48].
In fibrin 3D skin substitutes, the integration of ADSCs into the hypodermis leads them to differentiate
into adipocytes, thus impacting the cell behavior of the upper epidermis layer of the substitute
in vitro [49]. Many investigations went even further, using precursors of ECM, biomaterials scaffold,
hydrogels, and electrospinning procedures to induce rapid wound closure and to increase epidermis
thickness. However, an interesting approach has been presented by Chan et al., who used different
biomaterials in one skin substitute to drive ADSC differentiation into different cell lineages [50].
In injured sites, ADSCs were recruited and were migrated by increasing their expression of
CXCR-4 molecules, which led to modulating the inflammatory phenotype of local immune cells to
a healing anti-inflammatory one. Their presence was critical to drive the inflammatory profile of
macrophages, T, B, and dendritic cells initiating, and thus the proliferation and remodeling phases
of wound healing [51,52]. Their action was likely activated by TGF-B or GDF11 or both of them [53].
Recently, ADSCs have been transfected with MicroRNA(miR)-146a and the resulting miR-enriched
secretome strongly presented with angiogenic and anti-inflammatory capacities [54].
Additionally, preconditioning with inflammatory or pro-inflammatory cytokines has improved
their responses to cancer and inflammation in addition to increasing their survival [55-58]. Several
reports are in favor of optimizing the therapeutic benefit of ADSCs because of cytokine combination,
including TGF-8 and TNF-«. TGF-f was targeted by the integrin «86 and was secreted by the epithelial
cells to modulate skin immune surveillance and the ADSC microenvironment [59]. The latter was
dependent of IL-6 when initiating the inflammatory phase of wound healing. On this fact, ADSCs
were likely stimulated by IL-6 to autoinduce and their secretion of TNF-«, b-FGF, VEGF, TLR2, TLR4,
IL-6, TGF-8, and GDF11.
DF and ADSCs were demonstrated to modulate and address their microenvironment by secreting
the growth factor as TGF-$ and ECM to optimize keratinocyte and DF involvement in the healing
process [46—48,60]. However, ADSCs also interacted with microvascular endothelial cells to secrete the
increasing levels of IL-6, IL-8, and MCP-1 to modulate skin inflammation [61].
Recently, the secretome of MSCs have drawn more attention as a mechanism governing skin
repair and regeneration by managing their microenvironment with growth factors and cytokine
secretion [21,22]. In wound healing, ADSC extracellular vesicles were involved in the migration
and proliferation of DF and keratinocytes, including collagen and elastin deposition [8,11,12]. In the
same way, the authors reported similar positive effects of ADSC-conditioned media on skin aging
manifestations [38,62—64] and similar results were found when using the conditioned media derived
from other MSCs [65,66].
This interplay between ADSC secretion and the other epidermal progenitors seem to orchestrate
the hierarchical process of regeneration and repair by locally inducing ADSC-residents’ crosstalk in
aging or after injury [11,65,67,68]. Nevertheless, when derived from the same microenvironment,
location, and was seen in the same human dermo-epidermo skin substitute (DESS), MSCs from
forskin, palmer skin, and tonsils presented similar graft morphology, keratinocyte proliferation and
differentiation, and maturation [69].
4. ADSCs Advancements in Skin Therapy
ADSCs are found in higher frequencies in liposuctions, they can differentiate into multiple cell
lineages, and they are safely transplanted in both autologous and allogeneic settings. Used expanded
or not-expanded or within the SVF, the performing therapeutic applications were very promising,
suggesting that their potential use in regenerative medicine is becoming a real therapeutic alternative
for wound management strategies to various skin-related disorders and to rescue the disadvantages
or limitations in conventional treatments [70]. ADSCs appeared more proliferative and maintained
their potential to differentiate into cells of mesodermal origin during aging, which was contrary to
Skin injury is expected to be the first application where using ADSCs might be justified to
different extents. Their use has been shown to promote fat tissue survival after transplantation with
fat used in the case of soft tissue augmentation surgery, in breast augmentation, and facial tissue
defects [73-77]. Additionally, their multiple applications increased the rate of cell proliferation, thus
leading to accelerated wound healing [78]. Their use helped the emergence of a near-natural skin
concept in terms of appearance, texture, color, and metabolic properties. Other investigations have
used autologous or allogenic ADSCs in the treatment of Crohn’s disease, critical limb ischemia, diabetic
foot ulcers, and burns [63,79-82]. In combination with fat or platelet-rich lysate, skin engraftment, and
reconstitution have been improved in human and animal models [83-85]. Additionally, platelets lysate
appeared to support ADSC proliferation and differentiation in vitro and might replace the use of fetal
bovine serum during cell expansion [86].
In wound healing and burns, these cells contribute to the phases of tissue repair and skin
reconstitution to different extents, either by their ability to proliferate and differentiate or by secreting
different growth factors and cytokines involved in these phases (Figure 1). Tissue engineering has added
many insights into the way ADSCs can be used in skin repair. Klar et al. performed a 3-dimension
DESS, characterized as the most near-natural skin substitute that is also able to present the patient skin
coloration by adding his own melanocytes to pigment and to preserve the skin from UV [70,87-89].
Different biomaterials have been investigated to support the expansion and the growth of skin
cells with the aim of obtaining an artificial skin substitute, and most of them used SVF or ADSCs. The
latter has proven to be efficient in the formation of cell sheets by increasing their ECM secretion in the
presence of a collagen scaffold or not [89-91].
8 GDFII TuR2, TuR4/ GOFAL
1L6, LAB, IL-8, 1L-10
GpFi1 | CXCR-4 expression Desmin,
PDGF, IL-6 TGF, TNF-a secretion
Ls b-FGF, VEGF, GDFI1
Cell m nm ADSCs differentiation, Skin cell
_ production, production of ECM
migration to outside the dermis
<4 PRODUCTION & REMODELING
and in the rejuvenation process. ADSCs act on fibroblasts, macrophages, and skin cells through their
secreted growth factors. GDF11 and TGF-f are present in almost all the phases, amplifying fibroblasts,
macrophages, and ADSC secretion, leading to immune responses, cell proliferation, and angiogenesis.
However, their interactions are more relevant during proliferation phases where GDF11 might induce
TFG-£ induction in a spatio-temporal status, in addition to boosting fibroblast proliferation, resulting
in the production of skin cells presenting young profiles. GDF11: growth differentiation factor, TGF-B:
transforming growth factor, ECM: extracellular matrix, PDGF: platelets derived growth factor, Il-1,6,8,10:
interleukin-1, TNF-«: tumor necrosis factor-«, b-FGF: basic-fibroblast growth factor, VEGF: vascular
endothelial growth factor, CXCR-4: C motif chemokine receptor 4, SDF-1: stromal derived factor-1,
TLR2, 4: toll-like receptor2,4, GM-CSF: granulocyte monocyte-colony stimulating factor, IGF: insulin
growth factor, MMP-1,-2, -9: matrix metalloproteinase-1, -2, -9, and «-SMA: «-smooth muscle actin.
By their immune effects, ADSCs modulated inflammation during wound healing to initiate tissue
reconstitution [71,72,83,84]. The inflammatory status was amplified by aging, where the accumulation
of senescent cells resulted in the increase in proinflammatory factors such as IL-6, IL-8, and TNF-«,
which are mostly associated with chronic inflammation. The production of IL-B paves the way for
this inflammatory-aging [92,93]. ADSCs secrete TGF-B, and together with IL-18 and IL-6, increase
macrophage recruitment and their polarization from M1 to M2 [94], followed by a phase of secretion
of anti-inflammatory cytokines [79,95]. In vitro, conditioned media of ADSCs have been reported to
stimulate macrophages and to increase secretion on TNF and IL-10 anti-inflammatory cytokines, which
stimulated wound healing [96].
The presence of a developed vascularization strongly impacted this macrophage’s phenotype
changes, likely through the paracrine effects of dermal cells, and principally, the ADSCs. In the
early stages of the burn’s rat model, CD68+ nitric oxide synthase+ (iNOS) proinflammatory M1
macrophage infiltrated the DESS graft and were polarized to CD68+ CD206+ M2 macrophages with a
less inflammatory profile and contributed to wound healing three weeks later [95]. Vascularization
also helped the infiltration of skin graft by monocytes/macrophages CD11b+ CD68+, induced by
endothelial cells lining the blood vessels [97]. These endothelial cells interacted with ADSCs to increase
their proinflammatory growth factor secretion as IL-6, IL-8, and MCP-1 [61].
A lot of evidence suggests that ADSCs and DF are able to migrate into injured skin or the upper
epidermis to regenerate senescent cells and to repopulate the skin. SDF-1 was revealed to be the
constitutively and mostly expressed protein involved in human skin cell migration in normal and in
damaged tissues [29,98,99]. This protein appeared to be even more upregulated in some human skin
disorders such as psoriasis, basal cell carcinoma, and squamous cell carcinoma. DF is the major source
of SDF-1, revealed by double immunostaining and heat shock protein 47 (HSP47), and is considered
to be the fibroblast’s markers. ADSCs have proved to overexpress SDF-1 to be recruited into the
damaged site [99,100], and inversely, this factor stimulates their paracrine, proliferation, and migration
abilities [101-104]. When treated with the adipose tissue extracellular fraction, fibroblasts improved
their motility through increasing CD44 and N-cadherin expression [105]. SDF-1 activated keratinocytes
proliferation by interacting with its receptor CXCR-4 [29]. This SDF-1/CXCR-4 axis is recognized to be
the key tool in cell homing and migration in normal and injured tissue and provides increased insights
into cancer development and metastasis.
A lot of evidence suggests the involvement of ADSCs in inducing neoangiogenesis in tissue repair
and wound healing. They secrete factors such as VEGF, PDGF, IGF, HGF, b-FGF, SDF-1, TGF-B, and
GDF11, proving the efficiency of stimulating the differentiation of ADSCs and DF into endothelial cells,
as reported recently [78,79,94,106-108]. This differentiation appeared to be associated with apoptosis
prevention and found application, particularly in treating critical limb ischemia [79]. Inducing
microenvironment changes by the overexpression of SDF-1 in DF led to keratinocyte proliferation and
ADSC recruitment, providing that a neovascularization has taken place together with the increase of
ECM secretion, thus promoting the remodeling phase of healing [29,105,109]. Adipose tissue extract
paved the way for ADSCs and accelerated wound healing and improved angiogenesis via the increased
Other evidence of the potential differentiation of ADSCs into endothelial progenitor cells has
been reported recently. ADSCs interacted with endothelial cells and macrophages to increase MCP-1
and VEGF secretion in order to regulate angiogenesis [61,111]. Indeed, these factors provide for the
formation of new vessels during the proliferative phase. Cross interactions between ADSCs, DFs, and
macrophages added to the growth factors and ECM secretion derived from the microenvironment to
became propitious to accelerating neovascularization. Moreover, ADSCs expressed HIF-1« regulating
VEGF gene expression in endothelial cells [112,113]. Others have confirmed the stimulation of
ADSCs proliferation and keratinocytes chemoattraction via HIF-1a and VEGF, which are involved in
angiogenesis and are facilitated by MMP [114,115]. Recently, SDF-1 has been released, together with
HIF-1« in exosomes of ADSCs overexpressing miR-21, and potentially promotes angiogenesis [116].
Similar results were reported recently when using multiple injections of autologous ADSCs to burn
wounds in the animal model, where angiogenesis was found to have an enhanced association with the
increase in VEGF expression [78].
In chronic radiation wounds, ADSCs also stimulated DF to proliferate and increase VEGF secretion,
consequently enhancing the capillary density [117]. This vascularization is crucial because it permits
the granulation tissue formation and graft recovery through a spatiotemporal infiltration of the dermal
layer with granulocytes (HIS48*) and host-derived monocytes/macrophages (CD11b*, CD68*) [97].
In this work, endothelial progenitors and ADSCs derived from human SVF were used to develop the
vasculature in a collagen type I-based dermal component in vitro.
During the proliferation phase, the cytokines and chemokines secreted by these ADSCs cells
were involved in several fibroblast characteristics, such as cell proliferation, migration, specifically
In [5]:
# =========================================
# Etape 5 : Extraction d'entités biomédicales
# =========================================

import requests
import hashlib

def query_plain(text, url="http://bern2.korea.ac.kr/plain"):
    """API de liaison d'entités biomédicales"""
    return requests.post(url, json={'text': str(text)}).json()

entity_list = []

# Extraire les entités pour chaque phrase,
# on ignore la dernière phrase si elle est incomplète
for s in sentences[:-1]:
    entity_list.append(query_plain(s))

# Liste finale des entités annotées
parsed_entities = []

# Vérification et parsing des entités
for entities in entity_list:
    e = []

    # Vérification des annotations
    # si aucune entité n'est trouvée, on ajoute le texte brut
    if not entities.get('annotations'):
        parsed_entities.append({
            'text': entities['text'],
            'text_sha256': hashlib.sha256(entities['text'].encode('utf-8')).hexdigest()
        })
        continue

    # Extraction des détails d'entités
    for entity in entities['annotations']:
        other_ids = [id for id in entity['id'] if not id.startswith("BERN")]
        entity_type = entity['obj']
        entity_name = entities['text'][entity['span']['begin']:entity['span']['end']]

        # Gestion des ID d'entité
        try:
            entity_id = [id for id in entity['id'] if id.startswith("BERN")][0]
        except IndexError:
            entity_id = entity_name
        e.append({
            'entity_id': entity_id,
            'other_ids': other_ids,
            'entity_type': entity_type,
            'entity': entity_name
        })

    # Ajout des entités extraites
    parsed_entities.append({
        'entities': e,
        'text': entities['text'],
        'text_sha256': hashlib.sha256(entities['text'].encode('utf-8')).hexdigest()
    })

# Vérification finale
print(f"Nombre de phrases avec entités : {len(parsed_entities)}")
print("Exemple d'entités :", parsed_entities[:2])
Nombre de phrases avec entités : 113
Exemple d'entités : [{'entities': [{'entity_id': 'mesenchymal/stromal stem cells', 'other_ids': ['CUI-less'], 'entity_type': 'cell_type', 'entity': 'mesenchymal/stromal stem cells'}, {'entity_id': 'MSCs', 'other_ids': ['CUI-less'], 'entity_type': 'cell_line', 'entity': 'MSCs'}], 'text': 'Multipotent mesenchymal/stromal stem cells (MSCs) have been identified as residual stem cells in almost all adult organs, especially within adipose tissue (AT).', 'text_sha256': '2a2e4b44c5192a69d25a81da08e5db7a787f698b664be466159831b67fd3198a'}, {'entities': [{'entity_id': 'mesenchymal cell', 'other_ids': ['CL:0008019'], 'entity_type': 'cell_type', 'entity': 'mesenchymal cell'}, {'entity_id': 'stromal vascular fraction', 'other_ids': ['CUI-less'], 'entity_type': 'cell_type', 'entity': 'stromal vascular fraction'}], 'text': 'These cells present, in vitro, the typical mesenchymal cell characteristics and are isolated within the stromal vascular fraction (SVF) [1,2].', 'text_sha256': 'bed316fefd5bcb89131aa4b9a69e722f6fa8e370f5d4f1536484af4eb43ce9eb'}]
In [6]:
# =========================================
# Etape 6 : Connexion à la db Neo4J
# =========================================

from neo4j import GraphDatabase
import pandas as pd

host = os.getenv("HOST_PROD")
user = os.getenv("USER_PROD")
password = os.getenv("PASSWORD_PROD")

driver = GraphDatabase.driver(host,auth=(user, password))

def test_connection():
    try:
        with driver.session() as session:
            result = session.run("RETURN 'Connexion réussie' AS message")
            for record in result:
                print(record["message"])  # Affichera "Connexion réussie"
        print("Connexion à Neo4j établie avec succès.")
    except Exception as e:
        print("Erreur de connexion :", e)

test_connection()

def neo4j_query(query, params=None):
    with driver.session() as session:
        result = session.run(query, params)
        return pd.DataFrame([r.values() for r in result], columns=result.keys())
Connexion réussie
Connexion à Neo4j établie avec succès.

art-sentence.png

In [7]:
# =========================================
# Etape 7 : Insertion des données
# =========================================

for author in authors:
    neo4j_query("""
    MERGE (a:Author {name: $author})
    MERGE (b:Article {title: $title})
    MERGE (a)-[:WROTE]->(b)
    """, {'title': title, 'author': author})

# Vérification
print(f"Auteurs insérés : {', '.join(authors)}")
print(f"Titre inséré : {title}")
Auteurs insérés : Loubna Mazini, Luc Rochette, Brahim Admou, Said Amal, Gabriel Malka, Loubna Mazini, Luc Rochette, Brahim Admou, Said Amal, Gabriel Malka
Titre inséré : Hopes and Limits of Adipose-Derived Stem Cells (ADSCs) and Mesenchymal Stem Cells (MSCs) in Wound Healing

art-sentence.png

In [8]:
# =========================================
# Etape 8 : Insertion des phrases et des entités extraites
# =========================================

neo4j_query("""
MATCH (a:Article {title: $title})
UNWIND $data as row
MERGE (s:Sentence {id: row.text_sha256})
SET s.text = row.text
MERGE (a)-[:HAS_SENTENCE]->(s)
WITH s, row.entities as entities
UNWIND entities as entity
MERGE (e:Entity {id: entity.entity_id})
ON CREATE SET e.other_ids = entity.other_ids,
              e.name = entity.entity,
              e.type = entity.entity_type
MERGE (s)-[m:MENTIONS]->(e)
ON CREATE SET m.count = 1
ON MATCH SET m.count = m.count + 1
""", {'data': parsed_entities, 'title': title})

# Vérification
print(f"Nombre de phrases insérées : {len(parsed_entities)}")
Nombre de phrases insérées : 113
In [9]:
# =========================================
# Etape 9 : Extraction de relations
# =========================================

import itertools
from transformers import AutoTokenizer
from zero_shot_re import RelTaggerModel, RelationExtractor

# Chargement du modèle et du tokenizer
model = RelTaggerModel.from_pretrained("fractalego/fewrel-zero-shot")
tokenizer = AutoTokenizer.from_pretrained("bert-base-uncased")

# Définition des relations possibles
relations = ['associated', 'interacts', 'causes', 'treats', 'inhibits']

# Initialisation de l'extracteur de relations
extractor = RelationExtractor(model, tokenizer, relations)

# Filtrer les phrases contenant plusieurs entités
candidates = [s for s in parsed_entities if (s.get('entities')) and (len(s['entities']) > 1)]

predicted_rels = []

# Générer toutes les combinaisons possibles de paires d'entités
for c in candidates:
    combinations = itertools.combinations(
        [{'name': x['entity'], 'id': x['entity_id']} for x in c['entities']], 2
    )
    for combination in list(combinations):
        print(f"Processing combinations: {combination}")
        try:
            # Extraction de la relation probable
            ranked_rels = extractor.rank(
                text=c['text'].replace(",", ""),
                head=combination[0]['name'],
                tail=combination[1]['name']
            )

            # Vérifier le seuil de confiance
            if ranked_rels[0][1] > 0.85:
                predicted_rels.append({
                    'head': combination[0]['id'],
                    'tail': combination[1]['id'],
                    'type': ranked_rels[0][0],
                    'source': c['text_sha256']
                })
                print(f"Relation trouvée: {predicted_rels[-1]}")
        except Exception as e:
            print(f"Erreur: {e}")

# Vérification des relations extraites
print(f"Nombre de relations extraites : {len(predicted_rels)}")
Some weights of the model checkpoint at bert-large-uncased-whole-word-masking-finetuned-squad were not used when initializing BertModel: ['qa_outputs.weight', 'qa_outputs.bias']
- This IS expected if you are initializing BertModel from the checkpoint of a model trained on another task or with another architecture (e.g. initializing a BertForSequenceClassification model from a BertForPreTraining model).
- This IS NOT expected if you are initializing BertModel from the checkpoint of a model that you expect to be exactly identical (initializing a BertForSequenceClassification model from a BertForSequenceClassification model).
Processing combinations: ({'name': 'mesenchymal/stromal stem cells', 'id': 'mesenchymal/stromal stem cells'}, {'name': 'MSCs', 'id': 'MSCs'})
Erreur: The entity "MSCs" is not in the text.
Processing combinations: ({'name': 'mesenchymal cell', 'id': 'mesenchymal cell'}, {'name': 'stromal vascular fraction', 'id': 'stromal vascular fraction'})
Processing combinations: ({'name': 'adipose derived stem cells', 'id': 'adipose derived stem cells'}, {'name': 'ASCs', 'id': 'ASCs'})
Erreur: The entity "ASCs" is not in the text.
Processing combinations: ({'name': 'adipose derived stem cells', 'id': 'adipose derived stem cells'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Erreur: The entity "ADSCs" is not in the text.
Processing combinations: ({'name': 'adipose derived stem cells', 'id': 'adipose derived stem cells'}, {'name': 'T cells', 'id': 'T cells'})
Relation trouvée: {'head': 'adipose derived stem cells', 'tail': 'T cells', 'type': 'inhibits', 'source': '9aac7107e3ef76cb940e9435cac1dc2577a4d5575e72f8b930c153956ababf59'}
Processing combinations: ({'name': 'ASCs', 'id': 'ASCs'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Erreur: The entity "ASCs" is not in the text.
Processing combinations: ({'name': 'ASCs', 'id': 'ASCs'}, {'name': 'T cells', 'id': 'T cells'})
Erreur: The entity "ASCs" is not in the text.
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'T cells', 'id': 'T cells'})
Erreur: The entity "ADSCs" is not in the text.
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'adipogenic lineage', 'id': 'adipogenic lineage'})
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'bone marrow (BM)- and umbilical cord (UC)-MSCs', 'id': 'bone marrow (BM)- and umbilical cord (UC)-MSCs'})
Processing combinations: ({'name': 'adipogenic lineage', 'id': 'adipogenic lineage'}, {'name': 'bone marrow (BM)- and umbilical cord (UC)-MSCs', 'id': 'bone marrow (BM)- and umbilical cord (UC)-MSCs'})
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'younger cells', 'id': 'younger cells'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'younger cells', 'type': 'inhibits', 'source': '00e8e5d1ddbf25b66cac61d119edbfb550e3a2b7f63cf8f03c4ddc5f3f2aa552'}
Processing combinations: ({'name': 'keratinocytes', 'id': 'keratinocytes'}, {'name': 'fibroblasts', 'id': 'fibroblasts'})
Processing combinations: ({'name': 'keratinocytes', 'id': 'keratinocytes'}, {'name': 'melanocytes', 'id': 'melanocytes'})
Processing combinations: ({'name': 'fibroblasts', 'id': 'fibroblasts'}, {'name': 'melanocytes', 'id': 'melanocytes'})
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'keratinocytes', 'id': 'keratinocytes'})
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'dermal fibroblasts', 'id': 'dermal fibroblasts'})
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'DF', 'id': 'DF'})
Erreur: The entity "DF" is not in the text.
Processing combinations: ({'name': 'keratinocytes', 'id': 'keratinocytes'}, {'name': 'dermal fibroblasts', 'id': 'dermal fibroblasts'})
Processing combinations: ({'name': 'keratinocytes', 'id': 'keratinocytes'}, {'name': 'DF', 'id': 'DF'})
Erreur: The entity "DF" is not in the text.
Processing combinations: ({'name': 'dermal fibroblasts', 'id': 'dermal fibroblasts'}, {'name': 'DF', 'id': 'DF'})
Erreur: The entity "DF" is not in the text.
Processing combinations: ({'name': 'Senescent cells', 'id': 'Senescent cells'}, {'name': 'wrinkles', 'id': 'wrinkles'})
Relation trouvée: {'head': 'Senescent cells', 'tail': 'wrinkles', 'type': 'associated', 'source': 'e09c84d001307a8857892698333096448c750c8c7ae2a6371eb41dc66deb86a0'}
Processing combinations: ({'name': 'epithelial cells', 'id': 'epithelial cells'}, {'name': 'oxygen', 'id': 'oxygen'})
Relation trouvée: {'head': 'epithelial cells', 'tail': 'oxygen', 'type': 'inhibits', 'source': '278c5bc27e4e619de3b320e15ee02241d0911a9cd23ba849555fdeee669315c1'}
Processing combinations: ({'name': 'epithelial cells', 'id': 'epithelial cells'}, {'name': 'TGF-B', 'id': 'TGF-B'})
Processing combinations: ({'name': 'epithelial cells', 'id': 'epithelial cells'}, {'name': 'GDF11', 'id': 'GDF11'})
Processing combinations: ({'name': 'epithelial cells', 'id': 'epithelial cells'}, {'name': 'GDF15', 'id': 'GDF15'})
Processing combinations: ({'name': 'epithelial cells', 'id': 'epithelial cells'}, {'name': 'b-FGF', 'id': 'b-FGF'})
Processing combinations: ({'name': 'epithelial cells', 'id': 'epithelial cells'}, {'name': 'VEGF', 'id': 'VEGF'})
Processing combinations: ({'name': 'epithelial cells', 'id': 'epithelial cells'}, {'name': 'MMP-1', 'id': 'MMP-1'})
Processing combinations: ({'name': 'epithelial cells', 'id': 'epithelial cells'}, {'name': 'MMP-2', 'id': 'MMP-2'})
Processing combinations: ({'name': 'epithelial cells', 'id': 'epithelial cells'}, {'name': 'MMP-9', 'id': 'MMP-9'})
Processing combinations: ({'name': 'epithelial cells', 'id': 'epithelial cells'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'GDF11', 'id': 'GDF11'})
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'GDF15', 'id': 'GDF15'})
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'b-FGF', 'id': 'b-FGF'})
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'VEGF', 'id': 'VEGF'})
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'MMP-1', 'id': 'MMP-1'})
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'MMP-2', 'id': 'MMP-2'})
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'MMP-9', 'id': 'MMP-9'})
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'GDF15', 'id': 'GDF15'})
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'b-FGF', 'id': 'b-FGF'})
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'VEGF', 'id': 'VEGF'})
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'MMP-1', 'id': 'MMP-1'})
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'MMP-2', 'id': 'MMP-2'})
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'MMP-9', 'id': 'MMP-9'})
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'GDF15', 'id': 'GDF15'}, {'name': 'b-FGF', 'id': 'b-FGF'})
Processing combinations: ({'name': 'GDF15', 'id': 'GDF15'}, {'name': 'VEGF', 'id': 'VEGF'})
Processing combinations: ({'name': 'GDF15', 'id': 'GDF15'}, {'name': 'MMP-1', 'id': 'MMP-1'})
Processing combinations: ({'name': 'GDF15', 'id': 'GDF15'}, {'name': 'MMP-2', 'id': 'MMP-2'})
Processing combinations: ({'name': 'GDF15', 'id': 'GDF15'}, {'name': 'MMP-9', 'id': 'MMP-9'})
Processing combinations: ({'name': 'GDF15', 'id': 'GDF15'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'b-FGF', 'id': 'b-FGF'}, {'name': 'VEGF', 'id': 'VEGF'})
Processing combinations: ({'name': 'b-FGF', 'id': 'b-FGF'}, {'name': 'MMP-1', 'id': 'MMP-1'})
Processing combinations: ({'name': 'b-FGF', 'id': 'b-FGF'}, {'name': 'MMP-2', 'id': 'MMP-2'})
Processing combinations: ({'name': 'b-FGF', 'id': 'b-FGF'}, {'name': 'MMP-9', 'id': 'MMP-9'})
Processing combinations: ({'name': 'b-FGF', 'id': 'b-FGF'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'MMP-1', 'id': 'MMP-1'})
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'MMP-2', 'id': 'MMP-2'})
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'MMP-9', 'id': 'MMP-9'})
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'MMP-1', 'id': 'MMP-1'}, {'name': 'MMP-2', 'id': 'MMP-2'})
Processing combinations: ({'name': 'MMP-1', 'id': 'MMP-1'}, {'name': 'MMP-9', 'id': 'MMP-9'})
Processing combinations: ({'name': 'MMP-1', 'id': 'MMP-1'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'MMP-2', 'id': 'MMP-2'}, {'name': 'MMP-9', 'id': 'MMP-9'})
Processing combinations: ({'name': 'MMP-2', 'id': 'MMP-2'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'MMP-9', 'id': 'MMP-9'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'epidermal atrophy', 'id': 'epidermal atrophy'}, {'name': 'wrinkles', 'id': 'wrinkles'})
Relation trouvée: {'head': 'epidermal atrophy', 'tail': 'wrinkles', 'type': 'inhibits', 'source': 'f0d6b3e6b9edd3c9124f79b13927a7ff9593c0d5c1e1e4f2cea6703e09529645'}
Processing combinations: ({'name': 'epidermal atrophy', 'id': 'epidermal atrophy'}, {'name': 'pigmentation defects', 'id': 'pigmentation defects'})
Erreur: The entity "pigmentation defects" is not in the text.
Processing combinations: ({'name': 'wrinkles', 'id': 'wrinkles'}, {'name': 'pigmentation defects', 'id': 'pigmentation defects'})
Erreur: The entity "pigmentation defects" is not in the text.
Processing combinations: ({'name': 'epithelial cells', 'id': 'epithelial cells'}, {'name': 'DF', 'id': 'DF'})
Processing combinations: ({'name': 'epithelial cells', 'id': 'epithelial cells'}, {'name': 'Langerhans cells', 'id': 'Langerhans cells'})
Processing combinations: ({'name': 'epithelial cells', 'id': 'epithelial cells'}, {'name': 'melanocytes', 'id': 'melanocytes'})
Processing combinations: ({'name': 'epithelial cells', 'id': 'epithelial cells'}, {'name': 'impairment of skin', 'id': 'impairment of skin'})
Relation trouvée: {'head': 'epithelial cells', 'tail': 'impairment of skin', 'type': 'inhibits', 'source': '6a764fedce1d15f7aad25d388642b818f2654265d95d06d258f0d62ab40d5154'}
Processing combinations: ({'name': 'DF', 'id': 'DF'}, {'name': 'Langerhans cells', 'id': 'Langerhans cells'})
Processing combinations: ({'name': 'DF', 'id': 'DF'}, {'name': 'melanocytes', 'id': 'melanocytes'})
Processing combinations: ({'name': 'DF', 'id': 'DF'}, {'name': 'impairment of skin', 'id': 'impairment of skin'})
Relation trouvée: {'head': 'DF', 'tail': 'impairment of skin', 'type': 'causes', 'source': '6a764fedce1d15f7aad25d388642b818f2654265d95d06d258f0d62ab40d5154'}
Processing combinations: ({'name': 'Langerhans cells', 'id': 'Langerhans cells'}, {'name': 'melanocytes', 'id': 'melanocytes'})
Processing combinations: ({'name': 'Langerhans cells', 'id': 'Langerhans cells'}, {'name': 'impairment of skin', 'id': 'impairment of skin'})
Relation trouvée: {'head': 'Langerhans cells', 'tail': 'impairment of skin', 'type': 'inhibits', 'source': '6a764fedce1d15f7aad25d388642b818f2654265d95d06d258f0d62ab40d5154'}
Processing combinations: ({'name': 'melanocytes', 'id': 'melanocytes'}, {'name': 'impairment of skin', 'id': 'impairment of skin'})
Relation trouvée: {'head': 'melanocytes', 'tail': 'impairment of skin', 'type': 'inhibits', 'source': '6a764fedce1d15f7aad25d388642b818f2654265d95d06d258f0d62ab40d5154'}
Processing combinations: ({'name': 'DF', 'id': 'DF'}, {'name': 'epidermal cells', 'id': 'epidermal cells'})
Relation trouvée: {'head': 'DF', 'tail': 'epidermal cells', 'type': 'interacts', 'source': '5daba417bbcf5a0e4d7671a52f91bfb821ef8edc48dc0a6347a7046eca03f793'}
Processing combinations: ({'name': 'Epidermal cells', 'id': 'Epidermal cells'}, {'name': 'DF', 'id': 'DF'})
Relation trouvée: {'head': 'Epidermal cells', 'tail': 'DF', 'type': 'interacts', 'source': '6a1e0dda94011c1cbb31445834a71d4e56054ef0343089e2b5fa2769ca6c9aa4'}
Processing combinations: ({'name': 'DF', 'id': 'DF'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'DF', 'id': 'DF'}, {'name': 'collagen type I, type III', 'id': 'collagen type I, type III'})
Erreur: The entity "collagen type I, type III" is not in the text.
Processing combinations: ({'name': 'DF', 'id': 'DF'}, {'name': 'elastin', 'id': 'elastin'})
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'collagen type I, type III', 'id': 'collagen type I, type III'})
Erreur: The entity "collagen type I, type III" is not in the text.
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'elastin', 'id': 'elastin'})
Processing combinations: ({'name': 'collagen type I, type III', 'id': 'collagen type I, type III'}, {'name': 'elastin', 'id': 'elastin'})
Erreur: The entity "collagen type I, type III" is not in the text.
Processing combinations: ({'name': 'Collagen', 'id': 'Collagen'}, {'name': 'collagen', 'id': 'collagen'})
Processing combinations: ({'name': 'Collagen I and III', 'id': 'Collagen I and III'}, {'name': 'matrix metalloprotease 1', 'id': 'matrix metalloprotease 1'})
Relation trouvée: {'head': 'Collagen I and III', 'tail': 'matrix metalloprotease 1', 'type': 'inhibits', 'source': '756f37390186b9e7b84f2fc9b5ea14ab2be14f1e117084047a52a65c04512f54'}
Processing combinations: ({'name': 'Collagen I and III', 'id': 'Collagen I and III'}, {'name': 'MMP-1', 'id': 'MMP-1'})
Erreur: The entity "MMP-1" is not in the text.
Processing combinations: ({'name': 'Collagen I and III', 'id': 'Collagen I and III'}, {'name': 'keratinocyte', 'id': 'keratinocyte'})
Processing combinations: ({'name': 'Collagen I and III', 'id': 'Collagen I and III'}, {'name': 'DE', 'id': 'DE'})
Processing combinations: ({'name': 'Collagen I and III', 'id': 'Collagen I and III'}, {'name': 'endothelial cells', 'id': 'endothelial cells'})
Erreur: The entity "endothelial cells" is not in the text.
Processing combinations: ({'name': 'matrix metalloprotease 1', 'id': 'matrix metalloprotease 1'}, {'name': 'MMP-1', 'id': 'MMP-1'})
Erreur: The entity "MMP-1" is not in the text.
Processing combinations: ({'name': 'matrix metalloprotease 1', 'id': 'matrix metalloprotease 1'}, {'name': 'keratinocyte', 'id': 'keratinocyte'})
Processing combinations: ({'name': 'matrix metalloprotease 1', 'id': 'matrix metalloprotease 1'}, {'name': 'DE', 'id': 'DE'})
Processing combinations: ({'name': 'matrix metalloprotease 1', 'id': 'matrix metalloprotease 1'}, {'name': 'endothelial cells', 'id': 'endothelial cells'})
Erreur: The entity "endothelial cells" is not in the text.
Processing combinations: ({'name': 'MMP-1', 'id': 'MMP-1'}, {'name': 'keratinocyte', 'id': 'keratinocyte'})
Erreur: The entity "MMP-1" is not in the text.
Processing combinations: ({'name': 'MMP-1', 'id': 'MMP-1'}, {'name': 'DE', 'id': 'DE'})
Erreur: The entity "MMP-1" is not in the text.
Processing combinations: ({'name': 'MMP-1', 'id': 'MMP-1'}, {'name': 'endothelial cells', 'id': 'endothelial cells'})
Erreur: The entity "MMP-1" is not in the text.
Processing combinations: ({'name': 'keratinocyte', 'id': 'keratinocyte'}, {'name': 'DE', 'id': 'DE'})
Processing combinations: ({'name': 'keratinocyte', 'id': 'keratinocyte'}, {'name': 'endothelial cells', 'id': 'endothelial cells'})
Erreur: The entity "endothelial cells" is not in the text.
Processing combinations: ({'name': 'DE', 'id': 'DE'}, {'name': 'endothelial cells', 'id': 'endothelial cells'})
Erreur: The entity "endothelial cells" is not in the text.
Processing combinations: ({'name': 'elastin fibers', 'id': 'elastin fibers'}, {'name': 'dermis atrophy', 'id': 'dermis atrophy'})
Relation trouvée: {'head': 'elastin fibers', 'tail': 'dermis atrophy', 'type': 'inhibits', 'source': '338d93cb205120e85b91df5e017669557ac6277bdcc5eb7064148b209c66682d'}
Processing combinations: ({'name': 'elastin fibers', 'id': 'elastin fibers'}, {'name': 'MMP-2', 'id': 'MMP-2'})
Processing combinations: ({'name': 'dermis atrophy', 'id': 'dermis atrophy'}, {'name': 'MMP-2', 'id': 'MMP-2'})
Relation trouvée: {'head': 'dermis atrophy', 'tail': 'MMP-2', 'type': 'inhibits', 'source': '338d93cb205120e85b91df5e017669557ac6277bdcc5eb7064148b209c66682d'}
Processing combinations: ({'name': 'MMP', 'id': 'MMP'}, {'name': 'MMP', 'id': 'MMP'})
Relation trouvée: {'head': 'MMP', 'tail': 'MMP', 'type': 'inhibits', 'source': '431922ccf37f286806640e8e0d93310a54150e91ec56e5212fc7dcc68c63e711'}
Processing combinations: ({'name': 'MMP', 'id': 'MMP'}, {'name': 'TIMPs', 'id': 'TIMPs'})
Erreur: The entity "TIMPs" is not in the text.
Processing combinations: ({'name': 'MMP', 'id': 'MMP'}, {'name': 'TIMPs', 'id': 'TIMPs'})
Erreur: The entity "TIMPs" is not in the text.
Processing combinations: ({'name': 'MMP', 'id': 'MMP'}, {'name': 'collagen deficiencies', 'id': 'collagen deficiencies'})
Relation trouvée: {'head': 'MMP', 'tail': 'collagen deficiencies', 'type': 'inhibits', 'source': '601cf9edebd61591e6d660b6995a78f6302fe4c219144709a93fa75d328387d1'}
Processing combinations: ({'name': 'MMP', 'id': 'MMP'}, {'name': 'collagen', 'id': 'collagen'})
Relation trouvée: {'head': 'MMP', 'tail': 'collagen', 'type': 'inhibits', 'source': '601cf9edebd61591e6d660b6995a78f6302fe4c219144709a93fa75d328387d1'}
Processing combinations: ({'name': 'collagen deficiencies', 'id': 'collagen deficiencies'}, {'name': 'collagen', 'id': 'collagen'})
Relation trouvée: {'head': 'collagen deficiencies', 'tail': 'collagen', 'type': 'treats', 'source': '601cf9edebd61591e6d660b6995a78f6302fe4c219144709a93fa75d328387d1'}
Processing combinations: ({'name': 'telomeres', 'id': 'telomeres'}, {'name': 'oxygen', 'id': 'oxygen'})
Relation trouvée: {'head': 'telomeres', 'tail': 'oxygen', 'type': 'causes', 'source': '53bcde30559b44b31d51bd71c684b8d9af27548f854bbb3eb915bceb2a807071'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'stem', 'id': 'stem'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'stem', 'type': 'interacts', 'source': 'e58bb7ae54f9739f52c6b48715365bf94d95eada106fe33ef1b4c9e066018935'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'supporting cells', 'id': 'supporting cells'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'supporting cells', 'type': 'interacts', 'source': 'e58bb7ae54f9739f52c6b48715365bf94d95eada106fe33ef1b4c9e066018935'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'stem', 'id': 'stem'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'stem', 'type': 'interacts', 'source': 'e58bb7ae54f9739f52c6b48715365bf94d95eada106fe33ef1b4c9e066018935'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'supporting cells', 'id': 'supporting cells'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'supporting cells', 'type': 'interacts', 'source': 'e58bb7ae54f9739f52c6b48715365bf94d95eada106fe33ef1b4c9e066018935'}
Processing combinations: ({'name': 'stem', 'id': 'stem'}, {'name': 'supporting cells', 'id': 'supporting cells'})
Relation trouvée: {'head': 'stem', 'tail': 'supporting cells', 'type': 'interacts', 'source': 'e58bb7ae54f9739f52c6b48715365bf94d95eada106fe33ef1b4c9e066018935'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'wound', 'id': 'wound'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'wound', 'type': 'inhibits', 'source': '55fdea5b4b1554709cc2a4129ebe68f844a5f28f708a0fa8086beaaa0c3ec9d8'}
Processing combinations: ({'name': 'fibrin', 'id': 'fibrin'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'fibrin', 'id': 'fibrin'}, {'name': 'adipocytes', 'id': 'adipocytes'})
Relation trouvée: {'head': 'fibrin', 'tail': 'adipocytes', 'type': 'treats', 'source': 'c1de7ec4201a9277830cc787943c1ba235679c9ae321439739099f60740f1c80'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'adipocytes', 'id': 'adipocytes'})
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'CXCR-4 molecules', 'id': 'CXCR-4 molecules'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'CXCR-4 molecules', 'type': 'inhibits', 'source': 'a5fca3ab1e70cea52c90d164f06759db34f2bc49c37e20f17387d3914f42df8d'}
Processing combinations: ({'name': 'macrophages', 'id': 'macrophages'}, {'name': 'T, B, and dendritic cells', 'id': 'T, B, and dendritic cells'})
Erreur: The entity "T, B, and dendritic cells" is not in the text.
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'GDF11', 'id': 'GDF11'})
Relation trouvée: {'head': 'TGF-B', 'tail': 'GDF11', 'type': 'inhibits', 'source': '8bbc8c1ac704099e6a530c1ed503fda6770c273c58bb3c6a139e2c9234d00393'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'MicroRNA(miR)-146a', 'id': 'MicroRNA(miR)-146a'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'MicroRNA(miR)-146a', 'type': 'treats', 'source': '23ed79487f7710666336636fd67839cb2c78a0b4029dcf95140443c781733d79'}
Processing combinations: ({'name': 'cancer', 'id': 'cancer'}, {'name': 'inflammation', 'id': 'inflammation'})
Relation trouvée: {'head': 'cancer', 'tail': 'inflammation', 'type': 'inhibits', 'source': '09abde7f938f3f0b49a3a5d1ad7f39d6a9831cfcaf00e1c911d574323594ef26'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'TGF-8', 'id': 'TGF-8'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'TGF-8', 'type': 'inhibits', 'source': 'b0e09ee068c62d66a6ad4d1f7aa0f70d1bddee337225b05f01c0cd0e87386c9d'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'TNF-', 'id': 'TNF-'})
Erreur: The entity "TNF-" is not in the text.
Processing combinations: ({'name': 'TGF-8', 'id': 'TGF-8'}, {'name': 'TNF-', 'id': 'TNF-'})
Erreur: The entity "TNF-" is not in the text.
Processing combinations: ({'name': 'TGF-f', 'id': 'TGF-f'}, {'name': 'integrin 86', 'id': 'integrin 86'})
Relation trouvée: {'head': 'TGF-f', 'tail': 'integrin 86', 'type': 'inhibits', 'source': 'c7cecec509273bf726ec43abf0f7f8827bd519ec23e8ef28b644afa3a6d05ee7'}
Processing combinations: ({'name': 'TGF-f', 'id': 'TGF-f'}, {'name': 'epithelial cells', 'id': 'epithelial cells'})
Processing combinations: ({'name': 'TGF-f', 'id': 'TGF-f'}, {'name': 'ADSC', 'id': 'ADSC'})
Relation trouvée: {'head': 'TGF-f', 'tail': 'ADSC', 'type': 'inhibits', 'source': 'c7cecec509273bf726ec43abf0f7f8827bd519ec23e8ef28b644afa3a6d05ee7'}
Processing combinations: ({'name': 'integrin 86', 'id': 'integrin 86'}, {'name': 'epithelial cells', 'id': 'epithelial cells'})
Processing combinations: ({'name': 'integrin 86', 'id': 'integrin 86'}, {'name': 'ADSC', 'id': 'ADSC'})
Relation trouvée: {'head': 'integrin 86', 'tail': 'ADSC', 'type': 'inhibits', 'source': 'c7cecec509273bf726ec43abf0f7f8827bd519ec23e8ef28b644afa3a6d05ee7'}
Processing combinations: ({'name': 'epithelial cells', 'id': 'epithelial cells'}, {'name': 'ADSC', 'id': 'ADSC'})
Relation trouvée: {'head': 'epithelial cells', 'tail': 'ADSC', 'type': 'treats', 'source': 'c7cecec509273bf726ec43abf0f7f8827bd519ec23e8ef28b644afa3a6d05ee7'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'IL-6', 'id': 'IL-6'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'IL-6', 'type': 'inhibits', 'source': '333915bcca4b6fe0b443fd8c34bc3b973c31c12bdd0d0e5221a933e7e9248208'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'TNF-', 'id': 'TNF-'})
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'b-FGF', 'id': 'b-FGF'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'b-FGF', 'type': 'inhibits', 'source': '333915bcca4b6fe0b443fd8c34bc3b973c31c12bdd0d0e5221a933e7e9248208'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'VEGF', 'id': 'VEGF'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'VEGF', 'type': 'inhibits', 'source': '333915bcca4b6fe0b443fd8c34bc3b973c31c12bdd0d0e5221a933e7e9248208'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'TLR2', 'id': 'TLR2'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'TLR2', 'type': 'interacts', 'source': '333915bcca4b6fe0b443fd8c34bc3b973c31c12bdd0d0e5221a933e7e9248208'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'TLR4', 'id': 'TLR4'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'TLR4', 'type': 'interacts', 'source': '333915bcca4b6fe0b443fd8c34bc3b973c31c12bdd0d0e5221a933e7e9248208'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'IL-6', 'id': 'IL-6'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'IL-6', 'type': 'inhibits', 'source': '333915bcca4b6fe0b443fd8c34bc3b973c31c12bdd0d0e5221a933e7e9248208'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'TGF-8', 'id': 'TGF-8'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'TGF-8', 'type': 'inhibits', 'source': '333915bcca4b6fe0b443fd8c34bc3b973c31c12bdd0d0e5221a933e7e9248208'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'GDF11', 'id': 'GDF11'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'IL-6', 'id': 'IL-6'}, {'name': 'TNF-', 'id': 'TNF-'})
Processing combinations: ({'name': 'IL-6', 'id': 'IL-6'}, {'name': 'b-FGF', 'id': 'b-FGF'})
Processing combinations: ({'name': 'IL-6', 'id': 'IL-6'}, {'name': 'VEGF', 'id': 'VEGF'})
Relation trouvée: {'head': 'IL-6', 'tail': 'VEGF', 'type': 'inhibits', 'source': '333915bcca4b6fe0b443fd8c34bc3b973c31c12bdd0d0e5221a933e7e9248208'}
Processing combinations: ({'name': 'IL-6', 'id': 'IL-6'}, {'name': 'TLR2', 'id': 'TLR2'})
Processing combinations: ({'name': 'IL-6', 'id': 'IL-6'}, {'name': 'TLR4', 'id': 'TLR4'})
Processing combinations: ({'name': 'IL-6', 'id': 'IL-6'}, {'name': 'IL-6', 'id': 'IL-6'})
Processing combinations: ({'name': 'IL-6', 'id': 'IL-6'}, {'name': 'TGF-8', 'id': 'TGF-8'})
Processing combinations: ({'name': 'IL-6', 'id': 'IL-6'}, {'name': 'GDF11', 'id': 'GDF11'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'TNF-', 'id': 'TNF-'}, {'name': 'b-FGF', 'id': 'b-FGF'})
Processing combinations: ({'name': 'TNF-', 'id': 'TNF-'}, {'name': 'VEGF', 'id': 'VEGF'})
Processing combinations: ({'name': 'TNF-', 'id': 'TNF-'}, {'name': 'TLR2', 'id': 'TLR2'})
Processing combinations: ({'name': 'TNF-', 'id': 'TNF-'}, {'name': 'TLR4', 'id': 'TLR4'})
Processing combinations: ({'name': 'TNF-', 'id': 'TNF-'}, {'name': 'IL-6', 'id': 'IL-6'})
Processing combinations: ({'name': 'TNF-', 'id': 'TNF-'}, {'name': 'TGF-8', 'id': 'TGF-8'})
Processing combinations: ({'name': 'TNF-', 'id': 'TNF-'}, {'name': 'GDF11', 'id': 'GDF11'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'b-FGF', 'id': 'b-FGF'}, {'name': 'VEGF', 'id': 'VEGF'})
Processing combinations: ({'name': 'b-FGF', 'id': 'b-FGF'}, {'name': 'TLR2', 'id': 'TLR2'})
Processing combinations: ({'name': 'b-FGF', 'id': 'b-FGF'}, {'name': 'TLR4', 'id': 'TLR4'})
Processing combinations: ({'name': 'b-FGF', 'id': 'b-FGF'}, {'name': 'IL-6', 'id': 'IL-6'})
Processing combinations: ({'name': 'b-FGF', 'id': 'b-FGF'}, {'name': 'TGF-8', 'id': 'TGF-8'})
Processing combinations: ({'name': 'b-FGF', 'id': 'b-FGF'}, {'name': 'GDF11', 'id': 'GDF11'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'TLR2', 'id': 'TLR2'})
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'TLR4', 'id': 'TLR4'})
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'IL-6', 'id': 'IL-6'})
Relation trouvée: {'head': 'VEGF', 'tail': 'IL-6', 'type': 'inhibits', 'source': '333915bcca4b6fe0b443fd8c34bc3b973c31c12bdd0d0e5221a933e7e9248208'}
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'TGF-8', 'id': 'TGF-8'})
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'GDF11', 'id': 'GDF11'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'TLR2', 'id': 'TLR2'}, {'name': 'TLR4', 'id': 'TLR4'})
Processing combinations: ({'name': 'TLR2', 'id': 'TLR2'}, {'name': 'IL-6', 'id': 'IL-6'})
Processing combinations: ({'name': 'TLR2', 'id': 'TLR2'}, {'name': 'TGF-8', 'id': 'TGF-8'})
Processing combinations: ({'name': 'TLR2', 'id': 'TLR2'}, {'name': 'GDF11', 'id': 'GDF11'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'TLR4', 'id': 'TLR4'}, {'name': 'IL-6', 'id': 'IL-6'})
Processing combinations: ({'name': 'TLR4', 'id': 'TLR4'}, {'name': 'TGF-8', 'id': 'TGF-8'})
Processing combinations: ({'name': 'TLR4', 'id': 'TLR4'}, {'name': 'GDF11', 'id': 'GDF11'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'IL-6', 'id': 'IL-6'}, {'name': 'TGF-8', 'id': 'TGF-8'})
Processing combinations: ({'name': 'IL-6', 'id': 'IL-6'}, {'name': 'GDF11', 'id': 'GDF11'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'TGF-8', 'id': 'TGF-8'}, {'name': 'GDF11', 'id': 'GDF11'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'TGF-$', 'id': 'TGF-$'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'TGF-$', 'type': 'inhibits', 'source': '7e555a6819855936b634e6c6465642cf8da69d45236f75c5dd9823d521089f75'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'keratinocyte', 'id': 'keratinocyte'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'keratinocyte', 'type': 'inhibits', 'source': '7e555a6819855936b634e6c6465642cf8da69d45236f75c5dd9823d521089f75'}
Processing combinations: ({'name': 'TGF-$', 'id': 'TGF-$'}, {'name': 'keratinocyte', 'id': 'keratinocyte'})
Relation trouvée: {'head': 'TGF-$', 'tail': 'keratinocyte', 'type': 'inhibits', 'source': '7e555a6819855936b634e6c6465642cf8da69d45236f75c5dd9823d521089f75'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'microvascular endothelial cells', 'id': 'microvascular endothelial cells'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'microvascular endothelial cells', 'type': 'interacts', 'source': '59099ea6ffe1028e1b69d17469d776e09572c08316b0f6aa62fd29c7c47be8e9'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'IL-6', 'id': 'IL-6'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'IL-6', 'type': 'interacts', 'source': '59099ea6ffe1028e1b69d17469d776e09572c08316b0f6aa62fd29c7c47be8e9'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'IL-8', 'id': 'IL-8'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'IL-8', 'type': 'interacts', 'source': '59099ea6ffe1028e1b69d17469d776e09572c08316b0f6aa62fd29c7c47be8e9'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'MCP-1', 'id': 'MCP-1'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'MCP-1', 'type': 'interacts', 'source': '59099ea6ffe1028e1b69d17469d776e09572c08316b0f6aa62fd29c7c47be8e9'}
Processing combinations: ({'name': 'microvascular endothelial cells', 'id': 'microvascular endothelial cells'}, {'name': 'IL-6', 'id': 'IL-6'})
Relation trouvée: {'head': 'microvascular endothelial cells', 'tail': 'IL-6', 'type': 'interacts', 'source': '59099ea6ffe1028e1b69d17469d776e09572c08316b0f6aa62fd29c7c47be8e9'}
Processing combinations: ({'name': 'microvascular endothelial cells', 'id': 'microvascular endothelial cells'}, {'name': 'IL-8', 'id': 'IL-8'})
Relation trouvée: {'head': 'microvascular endothelial cells', 'tail': 'IL-8', 'type': 'interacts', 'source': '59099ea6ffe1028e1b69d17469d776e09572c08316b0f6aa62fd29c7c47be8e9'}
Processing combinations: ({'name': 'microvascular endothelial cells', 'id': 'microvascular endothelial cells'}, {'name': 'MCP-1', 'id': 'MCP-1'})
Relation trouvée: {'head': 'microvascular endothelial cells', 'tail': 'MCP-1', 'type': 'interacts', 'source': '59099ea6ffe1028e1b69d17469d776e09572c08316b0f6aa62fd29c7c47be8e9'}
Processing combinations: ({'name': 'IL-6', 'id': 'IL-6'}, {'name': 'IL-8', 'id': 'IL-8'})
Processing combinations: ({'name': 'IL-6', 'id': 'IL-6'}, {'name': 'MCP-1', 'id': 'MCP-1'})
Relation trouvée: {'head': 'IL-6', 'tail': 'MCP-1', 'type': 'inhibits', 'source': '59099ea6ffe1028e1b69d17469d776e09572c08316b0f6aa62fd29c7c47be8e9'}
Processing combinations: ({'name': 'IL-8', 'id': 'IL-8'}, {'name': 'MCP-1', 'id': 'MCP-1'})
Relation trouvée: {'head': 'IL-8', 'tail': 'MCP-1', 'type': 'interacts', 'source': '59099ea6ffe1028e1b69d17469d776e09572c08316b0f6aa62fd29c7c47be8e9'}
Processing combinations: ({'name': 'ADSC', 'id': 'ADSC'}, {'name': 'DF', 'id': 'DF'})
Relation trouvée: {'head': 'ADSC', 'tail': 'DF', 'type': 'causes', 'source': 'a252d064972ab2fdff27059ab3d4eff14b9cb60dafc8d72224a40f5bb8b8a6d9'}
Processing combinations: ({'name': 'ADSC', 'id': 'ADSC'}, {'name': 'keratinocytes', 'id': 'keratinocytes'})
Relation trouvée: {'head': 'ADSC', 'tail': 'keratinocytes', 'type': 'associated', 'source': 'a252d064972ab2fdff27059ab3d4eff14b9cb60dafc8d72224a40f5bb8b8a6d9'}
Processing combinations: ({'name': 'ADSC', 'id': 'ADSC'}, {'name': 'collagen', 'id': 'collagen'})
Relation trouvée: {'head': 'ADSC', 'tail': 'collagen', 'type': 'treats', 'source': 'a252d064972ab2fdff27059ab3d4eff14b9cb60dafc8d72224a40f5bb8b8a6d9'}
Processing combinations: ({'name': 'ADSC', 'id': 'ADSC'}, {'name': 'elastin', 'id': 'elastin'})
Relation trouvée: {'head': 'ADSC', 'tail': 'elastin', 'type': 'treats', 'source': 'a252d064972ab2fdff27059ab3d4eff14b9cb60dafc8d72224a40f5bb8b8a6d9'}
Processing combinations: ({'name': 'DF', 'id': 'DF'}, {'name': 'keratinocytes', 'id': 'keratinocytes'})
Relation trouvée: {'head': 'DF', 'tail': 'keratinocytes', 'type': 'associated', 'source': 'a252d064972ab2fdff27059ab3d4eff14b9cb60dafc8d72224a40f5bb8b8a6d9'}
Processing combinations: ({'name': 'DF', 'id': 'DF'}, {'name': 'collagen', 'id': 'collagen'})
Processing combinations: ({'name': 'DF', 'id': 'DF'}, {'name': 'elastin', 'id': 'elastin'})
Relation trouvée: {'head': 'DF', 'tail': 'elastin', 'type': 'interacts', 'source': 'a252d064972ab2fdff27059ab3d4eff14b9cb60dafc8d72224a40f5bb8b8a6d9'}
Processing combinations: ({'name': 'keratinocytes', 'id': 'keratinocytes'}, {'name': 'collagen', 'id': 'collagen'})
Processing combinations: ({'name': 'keratinocytes', 'id': 'keratinocytes'}, {'name': 'elastin', 'id': 'elastin'})
Processing combinations: ({'name': 'collagen', 'id': 'collagen'}, {'name': 'elastin', 'id': 'elastin'})
Relation trouvée: {'head': 'collagen', 'tail': 'elastin', 'type': 'interacts', 'source': 'a252d064972ab2fdff27059ab3d4eff14b9cb60dafc8d72224a40f5bb8b8a6d9'}
Processing combinations: ({'name': 'ADSC', 'id': 'ADSC'}, {'name': 'skin aging', 'id': 'skin aging'})
Erreur: The entity "ADSC" is not in the text.
Processing combinations: ({'name': 'ADSC', 'id': 'ADSC'}, {'name': 'MSCs', 'id': 'MSCs'})
Erreur: The entity "ADSC" is not in the text.
Processing combinations: ({'name': 'skin aging', 'id': 'skin aging'}, {'name': 'MSCs', 'id': 'MSCs'})
Relation trouvée: {'head': 'skin aging', 'tail': 'MSCs', 'type': 'inhibits', 'source': 'e3e288a39040f4740602cb049444214f746fc527af913020e7642a01c8d0757a'}
Processing combinations: ({'name': 'ADSC', 'id': 'ADSC'}, {'name': 'epidermal progenitors', 'id': 'epidermal progenitors'})
Relation trouvée: {'head': 'ADSC', 'tail': 'epidermal progenitors', 'type': 'interacts', 'source': '7bd541eae4e109ab86d71d2ea2ac858eea5ec8e9033478b487c783f65fcff89d'}
Processing combinations: ({'name': 'ADSC', 'id': 'ADSC'}, {'name': 'ADSC', 'id': 'ADSC'})
Processing combinations: ({'name': 'epidermal progenitors', 'id': 'epidermal progenitors'}, {'name': 'ADSC', 'id': 'ADSC'})
Relation trouvée: {'head': 'epidermal progenitors', 'tail': 'ADSC', 'type': 'interacts', 'source': '7bd541eae4e109ab86d71d2ea2ac858eea5ec8e9033478b487c783f65fcff89d'}
Processing combinations: ({'name': 'human', 'id': 'human'}, {'name': 'MSCs', 'id': 'MSCs'})
Processing combinations: ({'name': 'human', 'id': 'human'}, {'name': 'keratinocyte', 'id': 'keratinocyte'})
Relation trouvée: {'head': 'human', 'tail': 'keratinocyte', 'type': 'associated', 'source': '7a550455039dae6c09599d5339b9cd573cbde16c1e6366f8945ef81ba2233473'}
Processing combinations: ({'name': 'MSCs', 'id': 'MSCs'}, {'name': 'keratinocyte', 'id': 'keratinocyte'})
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'ADSCs', 'type': 'treats', 'source': '393538c05a69fce48295d56b9c3218410ef6f427a986a5ae2aa2a247a6361c59'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'multiple cell lineages', 'id': 'multiple cell lineages'})
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'multiple cell lineages', 'id': 'multiple cell lineages'})
Processing combinations: ({'name': 'SVF', 'id': 'SVF'}, {'name': 'skin-related disorders', 'id': 'skin-related disorders'})
Relation trouvée: {'head': 'SVF', 'tail': 'skin-related disorders', 'type': 'treats', 'source': '8b0cc83e43ecb1494424ddeddf1bbdbc21db8193f94fcea8aa2785499a2201c5'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'Crohns disease', 'id': 'Crohns disease'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'Crohns disease', 'type': 'treats', 'source': 'fffc480924c9b424bdb0835c34208f0de0281d968496e2db5be01e884bae41b8'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'critical limb ischemia', 'id': 'critical limb ischemia'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'critical limb ischemia', 'type': 'treats', 'source': 'fffc480924c9b424bdb0835c34208f0de0281d968496e2db5be01e884bae41b8'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'diabetic foot ulcers', 'id': 'diabetic foot ulcers'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'diabetic foot ulcers', 'type': 'causes', 'source': 'fffc480924c9b424bdb0835c34208f0de0281d968496e2db5be01e884bae41b8'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'burns', 'id': 'burns'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'burns', 'type': 'treats', 'source': 'fffc480924c9b424bdb0835c34208f0de0281d968496e2db5be01e884bae41b8'}
Processing combinations: ({'name': 'Crohns disease', 'id': 'Crohns disease'}, {'name': 'critical limb ischemia', 'id': 'critical limb ischemia'})
Relation trouvée: {'head': 'Crohns disease', 'tail': 'critical limb ischemia', 'type': 'causes', 'source': 'fffc480924c9b424bdb0835c34208f0de0281d968496e2db5be01e884bae41b8'}
Processing combinations: ({'name': 'Crohns disease', 'id': 'Crohns disease'}, {'name': 'diabetic foot ulcers', 'id': 'diabetic foot ulcers'})
Relation trouvée: {'head': 'Crohns disease', 'tail': 'diabetic foot ulcers', 'type': 'causes', 'source': 'fffc480924c9b424bdb0835c34208f0de0281d968496e2db5be01e884bae41b8'}
Processing combinations: ({'name': 'Crohns disease', 'id': 'Crohns disease'}, {'name': 'burns', 'id': 'burns'})
Relation trouvée: {'head': 'Crohns disease', 'tail': 'burns', 'type': 'causes', 'source': 'fffc480924c9b424bdb0835c34208f0de0281d968496e2db5be01e884bae41b8'}
Processing combinations: ({'name': 'critical limb ischemia', 'id': 'critical limb ischemia'}, {'name': 'diabetic foot ulcers', 'id': 'diabetic foot ulcers'})
Relation trouvée: {'head': 'critical limb ischemia', 'tail': 'diabetic foot ulcers', 'type': 'causes', 'source': 'fffc480924c9b424bdb0835c34208f0de0281d968496e2db5be01e884bae41b8'}
Processing combinations: ({'name': 'critical limb ischemia', 'id': 'critical limb ischemia'}, {'name': 'burns', 'id': 'burns'})
Relation trouvée: {'head': 'critical limb ischemia', 'tail': 'burns', 'type': 'causes', 'source': 'fffc480924c9b424bdb0835c34208f0de0281d968496e2db5be01e884bae41b8'}
Processing combinations: ({'name': 'diabetic foot ulcers', 'id': 'diabetic foot ulcers'}, {'name': 'burns', 'id': 'burns'})
Relation trouvée: {'head': 'diabetic foot ulcers', 'tail': 'burns', 'type': 'causes', 'source': 'fffc480924c9b424bdb0835c34208f0de0281d968496e2db5be01e884bae41b8'}
Processing combinations: ({'name': 'platelet', 'id': 'platelet'}, {'name': 'human', 'id': 'human'})
Erreur: The entity "platelet" is not in the text.
Processing combinations: ({'name': 'platelets', 'id': 'platelets'}, {'name': 'ADSC', 'id': 'ADSC'})
Relation trouvée: {'head': 'platelets', 'tail': 'ADSC', 'type': 'inhibits', 'source': '95ddf2f4bd8646994a5c308f055be3caa6195625ea38a43c96e0f95821088d05'}
Processing combinations: ({'name': 'platelets', 'id': 'platelets'}, {'name': 'bovine', 'id': 'bovine'})
Relation trouvée: {'head': 'platelets', 'tail': 'bovine', 'type': 'treats', 'source': '95ddf2f4bd8646994a5c308f055be3caa6195625ea38a43c96e0f95821088d05'}
Processing combinations: ({'name': 'ADSC', 'id': 'ADSC'}, {'name': 'bovine', 'id': 'bovine'})
Relation trouvée: {'head': 'ADSC', 'tail': 'bovine', 'type': 'inhibits', 'source': '95ddf2f4bd8646994a5c308f055be3caa6195625ea38a43c96e0f95821088d05'}
Processing combinations: ({'name': 'patient', 'id': 'patient'}, {'name': 'melanocytes', 'id': 'melanocytes'})
Relation trouvée: {'head': 'patient', 'tail': 'melanocytes', 'type': 'treats', 'source': '126bfd5a59f353282dcefef334286fac18cf1abb91b9846bbb8cbcb25875bfcb'}
Processing combinations: ({'name': 'skin cells', 'id': 'skin cells'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Erreur: The entity "ADSCs" is not in the text.
Processing combinations: ({'name': 'cell sheets', 'id': 'cell sheets'}, {'name': 'collagen', 'id': 'collagen'})
Processing combinations: ({'name': '8', 'id': '8'}, {'name': 'GDFII', 'id': 'GDFII'})
Processing combinations: ({'name': '8', 'id': '8'}, {'name': 'TuR2', 'id': 'TuR2'})
Processing combinations: ({'name': '8', 'id': '8'}, {'name': 'TuR4', 'id': 'TuR4'})
Erreur: The entity "TuR4" is not in the text.
Processing combinations: ({'name': '8', 'id': '8'}, {'name': 'GOFAL 1L6', 'id': 'GOFAL 1L6'})
Processing combinations: ({'name': '8', 'id': '8'}, {'name': 'LAB', 'id': 'LAB'})
Processing combinations: ({'name': '8', 'id': '8'}, {'name': 'IL-8', 'id': 'IL-8'})
Processing combinations: ({'name': '8', 'id': '8'}, {'name': '1L-10 GpFi1', 'id': '1L-10 GpFi1'})
Processing combinations: ({'name': '8', 'id': '8'}, {'name': 'CXCR-4', 'id': 'CXCR-4'})
Processing combinations: ({'name': '8', 'id': '8'}, {'name': 'Desmin', 'id': 'Desmin'})
Processing combinations: ({'name': '8', 'id': '8'}, {'name': 'PDGF', 'id': 'PDGF'})
Processing combinations: ({'name': '8', 'id': '8'}, {'name': 'IL-', 'id': 'IL-'})
Erreur: The entity "IL-" is not in the text.
Processing combinations: ({'name': '8', 'id': '8'}, {'name': 'TNF-a', 'id': 'TNF-a'})
Processing combinations: ({'name': '8', 'id': '8'}, {'name': 'VEGF', 'id': 'VEGF'})
Processing combinations: ({'name': '8', 'id': '8'}, {'name': 'GDFI1', 'id': 'GDFI1'})
Processing combinations: ({'name': '8', 'id': '8'}, {'name': 'm nm', 'id': 'm nm'})
Processing combinations: ({'name': '8', 'id': '8'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'GDFII', 'id': 'GDFII'}, {'name': 'TuR2', 'id': 'TuR2'})
Processing combinations: ({'name': 'GDFII', 'id': 'GDFII'}, {'name': 'TuR4', 'id': 'TuR4'})
Erreur: The entity "TuR4" is not in the text.
Processing combinations: ({'name': 'GDFII', 'id': 'GDFII'}, {'name': 'GOFAL 1L6', 'id': 'GOFAL 1L6'})
Processing combinations: ({'name': 'GDFII', 'id': 'GDFII'}, {'name': 'LAB', 'id': 'LAB'})
Processing combinations: ({'name': 'GDFII', 'id': 'GDFII'}, {'name': 'IL-8', 'id': 'IL-8'})
Processing combinations: ({'name': 'GDFII', 'id': 'GDFII'}, {'name': '1L-10 GpFi1', 'id': '1L-10 GpFi1'})
Processing combinations: ({'name': 'GDFII', 'id': 'GDFII'}, {'name': 'CXCR-4', 'id': 'CXCR-4'})
Processing combinations: ({'name': 'GDFII', 'id': 'GDFII'}, {'name': 'Desmin', 'id': 'Desmin'})
Processing combinations: ({'name': 'GDFII', 'id': 'GDFII'}, {'name': 'PDGF', 'id': 'PDGF'})
Processing combinations: ({'name': 'GDFII', 'id': 'GDFII'}, {'name': 'IL-', 'id': 'IL-'})
Erreur: The entity "IL-" is not in the text.
Processing combinations: ({'name': 'GDFII', 'id': 'GDFII'}, {'name': 'TNF-a', 'id': 'TNF-a'})
Processing combinations: ({'name': 'GDFII', 'id': 'GDFII'}, {'name': 'VEGF', 'id': 'VEGF'})
Processing combinations: ({'name': 'GDFII', 'id': 'GDFII'}, {'name': 'GDFI1', 'id': 'GDFI1'})
Processing combinations: ({'name': 'GDFII', 'id': 'GDFII'}, {'name': 'm nm', 'id': 'm nm'})
Processing combinations: ({'name': 'GDFII', 'id': 'GDFII'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'TuR2', 'id': 'TuR2'}, {'name': 'TuR4', 'id': 'TuR4'})
Erreur: The entity "TuR4" is not in the text.
Processing combinations: ({'name': 'TuR2', 'id': 'TuR2'}, {'name': 'GOFAL 1L6', 'id': 'GOFAL 1L6'})
Processing combinations: ({'name': 'TuR2', 'id': 'TuR2'}, {'name': 'LAB', 'id': 'LAB'})
Processing combinations: ({'name': 'TuR2', 'id': 'TuR2'}, {'name': 'IL-8', 'id': 'IL-8'})
Processing combinations: ({'name': 'TuR2', 'id': 'TuR2'}, {'name': '1L-10 GpFi1', 'id': '1L-10 GpFi1'})
Processing combinations: ({'name': 'TuR2', 'id': 'TuR2'}, {'name': 'CXCR-4', 'id': 'CXCR-4'})
Processing combinations: ({'name': 'TuR2', 'id': 'TuR2'}, {'name': 'Desmin', 'id': 'Desmin'})
Processing combinations: ({'name': 'TuR2', 'id': 'TuR2'}, {'name': 'PDGF', 'id': 'PDGF'})
Processing combinations: ({'name': 'TuR2', 'id': 'TuR2'}, {'name': 'IL-', 'id': 'IL-'})
Erreur: The entity "IL-" is not in the text.
Processing combinations: ({'name': 'TuR2', 'id': 'TuR2'}, {'name': 'TNF-a', 'id': 'TNF-a'})
Processing combinations: ({'name': 'TuR2', 'id': 'TuR2'}, {'name': 'VEGF', 'id': 'VEGF'})
Processing combinations: ({'name': 'TuR2', 'id': 'TuR2'}, {'name': 'GDFI1', 'id': 'GDFI1'})
Processing combinations: ({'name': 'TuR2', 'id': 'TuR2'}, {'name': 'm nm', 'id': 'm nm'})
Processing combinations: ({'name': 'TuR2', 'id': 'TuR2'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'TuR4', 'id': 'TuR4'}, {'name': 'GOFAL 1L6', 'id': 'GOFAL 1L6'})
Erreur: The entity "TuR4" is not in the text.
Processing combinations: ({'name': 'TuR4', 'id': 'TuR4'}, {'name': 'LAB', 'id': 'LAB'})
Erreur: The entity "TuR4" is not in the text.
Processing combinations: ({'name': 'TuR4', 'id': 'TuR4'}, {'name': 'IL-8', 'id': 'IL-8'})
Erreur: The entity "TuR4" is not in the text.
Processing combinations: ({'name': 'TuR4', 'id': 'TuR4'}, {'name': '1L-10 GpFi1', 'id': '1L-10 GpFi1'})
Erreur: The entity "TuR4" is not in the text.
Processing combinations: ({'name': 'TuR4', 'id': 'TuR4'}, {'name': 'CXCR-4', 'id': 'CXCR-4'})
Erreur: The entity "TuR4" is not in the text.
Processing combinations: ({'name': 'TuR4', 'id': 'TuR4'}, {'name': 'Desmin', 'id': 'Desmin'})
Erreur: The entity "TuR4" is not in the text.
Processing combinations: ({'name': 'TuR4', 'id': 'TuR4'}, {'name': 'PDGF', 'id': 'PDGF'})
Erreur: The entity "TuR4" is not in the text.
Processing combinations: ({'name': 'TuR4', 'id': 'TuR4'}, {'name': 'IL-', 'id': 'IL-'})
Erreur: The entity "TuR4" is not in the text.
Processing combinations: ({'name': 'TuR4', 'id': 'TuR4'}, {'name': 'TNF-a', 'id': 'TNF-a'})
Erreur: The entity "TuR4" is not in the text.
Processing combinations: ({'name': 'TuR4', 'id': 'TuR4'}, {'name': 'VEGF', 'id': 'VEGF'})
Erreur: The entity "TuR4" is not in the text.
Processing combinations: ({'name': 'TuR4', 'id': 'TuR4'}, {'name': 'GDFI1', 'id': 'GDFI1'})
Erreur: The entity "TuR4" is not in the text.
Processing combinations: ({'name': 'TuR4', 'id': 'TuR4'}, {'name': 'm nm', 'id': 'm nm'})
Erreur: The entity "TuR4" is not in the text.
Processing combinations: ({'name': 'TuR4', 'id': 'TuR4'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Erreur: The entity "TuR4" is not in the text.
Processing combinations: ({'name': 'GOFAL 1L6', 'id': 'GOFAL 1L6'}, {'name': 'LAB', 'id': 'LAB'})
Processing combinations: ({'name': 'GOFAL 1L6', 'id': 'GOFAL 1L6'}, {'name': 'IL-8', 'id': 'IL-8'})
Processing combinations: ({'name': 'GOFAL 1L6', 'id': 'GOFAL 1L6'}, {'name': '1L-10 GpFi1', 'id': '1L-10 GpFi1'})
Processing combinations: ({'name': 'GOFAL 1L6', 'id': 'GOFAL 1L6'}, {'name': 'CXCR-4', 'id': 'CXCR-4'})
Processing combinations: ({'name': 'GOFAL 1L6', 'id': 'GOFAL 1L6'}, {'name': 'Desmin', 'id': 'Desmin'})
Processing combinations: ({'name': 'GOFAL 1L6', 'id': 'GOFAL 1L6'}, {'name': 'PDGF', 'id': 'PDGF'})
Processing combinations: ({'name': 'GOFAL 1L6', 'id': 'GOFAL 1L6'}, {'name': 'IL-', 'id': 'IL-'})
Erreur: The entity "IL-" is not in the text.
Processing combinations: ({'name': 'GOFAL 1L6', 'id': 'GOFAL 1L6'}, {'name': 'TNF-a', 'id': 'TNF-a'})
Processing combinations: ({'name': 'GOFAL 1L6', 'id': 'GOFAL 1L6'}, {'name': 'VEGF', 'id': 'VEGF'})
Processing combinations: ({'name': 'GOFAL 1L6', 'id': 'GOFAL 1L6'}, {'name': 'GDFI1', 'id': 'GDFI1'})
Processing combinations: ({'name': 'GOFAL 1L6', 'id': 'GOFAL 1L6'}, {'name': 'm nm', 'id': 'm nm'})
Processing combinations: ({'name': 'GOFAL 1L6', 'id': 'GOFAL 1L6'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'LAB', 'id': 'LAB'}, {'name': 'IL-8', 'id': 'IL-8'})
Processing combinations: ({'name': 'LAB', 'id': 'LAB'}, {'name': '1L-10 GpFi1', 'id': '1L-10 GpFi1'})
Processing combinations: ({'name': 'LAB', 'id': 'LAB'}, {'name': 'CXCR-4', 'id': 'CXCR-4'})
Processing combinations: ({'name': 'LAB', 'id': 'LAB'}, {'name': 'Desmin', 'id': 'Desmin'})
Processing combinations: ({'name': 'LAB', 'id': 'LAB'}, {'name': 'PDGF', 'id': 'PDGF'})
Processing combinations: ({'name': 'LAB', 'id': 'LAB'}, {'name': 'IL-', 'id': 'IL-'})
Erreur: The entity "IL-" is not in the text.
Processing combinations: ({'name': 'LAB', 'id': 'LAB'}, {'name': 'TNF-a', 'id': 'TNF-a'})
Processing combinations: ({'name': 'LAB', 'id': 'LAB'}, {'name': 'VEGF', 'id': 'VEGF'})
Processing combinations: ({'name': 'LAB', 'id': 'LAB'}, {'name': 'GDFI1', 'id': 'GDFI1'})
Processing combinations: ({'name': 'LAB', 'id': 'LAB'}, {'name': 'm nm', 'id': 'm nm'})
Processing combinations: ({'name': 'LAB', 'id': 'LAB'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'IL-8', 'id': 'IL-8'}, {'name': '1L-10 GpFi1', 'id': '1L-10 GpFi1'})
Processing combinations: ({'name': 'IL-8', 'id': 'IL-8'}, {'name': 'CXCR-4', 'id': 'CXCR-4'})
Processing combinations: ({'name': 'IL-8', 'id': 'IL-8'}, {'name': 'Desmin', 'id': 'Desmin'})
Processing combinations: ({'name': 'IL-8', 'id': 'IL-8'}, {'name': 'PDGF', 'id': 'PDGF'})
Processing combinations: ({'name': 'IL-8', 'id': 'IL-8'}, {'name': 'IL-', 'id': 'IL-'})
Erreur: The entity "IL-" is not in the text.
Processing combinations: ({'name': 'IL-8', 'id': 'IL-8'}, {'name': 'TNF-a', 'id': 'TNF-a'})
Processing combinations: ({'name': 'IL-8', 'id': 'IL-8'}, {'name': 'VEGF', 'id': 'VEGF'})
Processing combinations: ({'name': 'IL-8', 'id': 'IL-8'}, {'name': 'GDFI1', 'id': 'GDFI1'})
Processing combinations: ({'name': 'IL-8', 'id': 'IL-8'}, {'name': 'm nm', 'id': 'm nm'})
Processing combinations: ({'name': 'IL-8', 'id': 'IL-8'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': '1L-10 GpFi1', 'id': '1L-10 GpFi1'}, {'name': 'CXCR-4', 'id': 'CXCR-4'})
Processing combinations: ({'name': '1L-10 GpFi1', 'id': '1L-10 GpFi1'}, {'name': 'Desmin', 'id': 'Desmin'})
Processing combinations: ({'name': '1L-10 GpFi1', 'id': '1L-10 GpFi1'}, {'name': 'PDGF', 'id': 'PDGF'})
Processing combinations: ({'name': '1L-10 GpFi1', 'id': '1L-10 GpFi1'}, {'name': 'IL-', 'id': 'IL-'})
Erreur: The entity "IL-" is not in the text.
Processing combinations: ({'name': '1L-10 GpFi1', 'id': '1L-10 GpFi1'}, {'name': 'TNF-a', 'id': 'TNF-a'})
Processing combinations: ({'name': '1L-10 GpFi1', 'id': '1L-10 GpFi1'}, {'name': 'VEGF', 'id': 'VEGF'})
Processing combinations: ({'name': '1L-10 GpFi1', 'id': '1L-10 GpFi1'}, {'name': 'GDFI1', 'id': 'GDFI1'})
Processing combinations: ({'name': '1L-10 GpFi1', 'id': '1L-10 GpFi1'}, {'name': 'm nm', 'id': 'm nm'})
Processing combinations: ({'name': '1L-10 GpFi1', 'id': '1L-10 GpFi1'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'CXCR-4', 'id': 'CXCR-4'}, {'name': 'Desmin', 'id': 'Desmin'})
Processing combinations: ({'name': 'CXCR-4', 'id': 'CXCR-4'}, {'name': 'PDGF', 'id': 'PDGF'})
Processing combinations: ({'name': 'CXCR-4', 'id': 'CXCR-4'}, {'name': 'IL-', 'id': 'IL-'})
Erreur: The entity "IL-" is not in the text.
Processing combinations: ({'name': 'CXCR-4', 'id': 'CXCR-4'}, {'name': 'TNF-a', 'id': 'TNF-a'})
Processing combinations: ({'name': 'CXCR-4', 'id': 'CXCR-4'}, {'name': 'VEGF', 'id': 'VEGF'})
Processing combinations: ({'name': 'CXCR-4', 'id': 'CXCR-4'}, {'name': 'GDFI1', 'id': 'GDFI1'})
Processing combinations: ({'name': 'CXCR-4', 'id': 'CXCR-4'}, {'name': 'm nm', 'id': 'm nm'})
Processing combinations: ({'name': 'CXCR-4', 'id': 'CXCR-4'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'Desmin', 'id': 'Desmin'}, {'name': 'PDGF', 'id': 'PDGF'})
Processing combinations: ({'name': 'Desmin', 'id': 'Desmin'}, {'name': 'IL-', 'id': 'IL-'})
Erreur: The entity "IL-" is not in the text.
Processing combinations: ({'name': 'Desmin', 'id': 'Desmin'}, {'name': 'TNF-a', 'id': 'TNF-a'})
Processing combinations: ({'name': 'Desmin', 'id': 'Desmin'}, {'name': 'VEGF', 'id': 'VEGF'})
Processing combinations: ({'name': 'Desmin', 'id': 'Desmin'}, {'name': 'GDFI1', 'id': 'GDFI1'})
Processing combinations: ({'name': 'Desmin', 'id': 'Desmin'}, {'name': 'm nm', 'id': 'm nm'})
Processing combinations: ({'name': 'Desmin', 'id': 'Desmin'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'IL-', 'id': 'IL-'})
Erreur: The entity "IL-" is not in the text.
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'TNF-a', 'id': 'TNF-a'})
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'VEGF', 'id': 'VEGF'})
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'GDFI1', 'id': 'GDFI1'})
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'm nm', 'id': 'm nm'})
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'IL-', 'id': 'IL-'}, {'name': 'TNF-a', 'id': 'TNF-a'})
Erreur: The entity "IL-" is not in the text.
Processing combinations: ({'name': 'IL-', 'id': 'IL-'}, {'name': 'VEGF', 'id': 'VEGF'})
Erreur: The entity "IL-" is not in the text.
Processing combinations: ({'name': 'IL-', 'id': 'IL-'}, {'name': 'GDFI1', 'id': 'GDFI1'})
Erreur: The entity "IL-" is not in the text.
Processing combinations: ({'name': 'IL-', 'id': 'IL-'}, {'name': 'm nm', 'id': 'm nm'})
Erreur: The entity "IL-" is not in the text.
Processing combinations: ({'name': 'IL-', 'id': 'IL-'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Erreur: The entity "IL-" is not in the text.
Processing combinations: ({'name': 'TNF-a', 'id': 'TNF-a'}, {'name': 'VEGF', 'id': 'VEGF'})
Processing combinations: ({'name': 'TNF-a', 'id': 'TNF-a'}, {'name': 'GDFI1', 'id': 'GDFI1'})
Processing combinations: ({'name': 'TNF-a', 'id': 'TNF-a'}, {'name': 'm nm', 'id': 'm nm'})
Processing combinations: ({'name': 'TNF-a', 'id': 'TNF-a'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'GDFI1', 'id': 'GDFI1'})
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'm nm', 'id': 'm nm'})
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'GDFI1', 'id': 'GDFI1'}, {'name': 'm nm', 'id': 'm nm'})
Processing combinations: ({'name': 'GDFI1', 'id': 'GDFI1'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'm nm', 'id': 'm nm'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'fibroblasts', 'id': 'fibroblasts'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'fibroblasts', 'type': 'associated', 'source': '2cba59c6fab1a14738311830015f1c3a127987e9e60ac7f08ce2bb25ee964345'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'macrophages', 'id': 'macrophages'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'macrophages', 'type': 'associated', 'source': '2cba59c6fab1a14738311830015f1c3a127987e9e60ac7f08ce2bb25ee964345'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'skin cells', 'id': 'skin cells'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'skin cells', 'type': 'treats', 'source': '2cba59c6fab1a14738311830015f1c3a127987e9e60ac7f08ce2bb25ee964345'}
Processing combinations: ({'name': 'fibroblasts', 'id': 'fibroblasts'}, {'name': 'macrophages', 'id': 'macrophages'})
Processing combinations: ({'name': 'fibroblasts', 'id': 'fibroblasts'}, {'name': 'skin cells', 'id': 'skin cells'})
Relation trouvée: {'head': 'fibroblasts', 'tail': 'skin cells', 'type': 'treats', 'source': '2cba59c6fab1a14738311830015f1c3a127987e9e60ac7f08ce2bb25ee964345'}
Processing combinations: ({'name': 'macrophages', 'id': 'macrophages'}, {'name': 'skin cells', 'id': 'skin cells'})
Relation trouvée: {'head': 'macrophages', 'tail': 'skin cells', 'type': 'associated', 'source': '2cba59c6fab1a14738311830015f1c3a127987e9e60ac7f08ce2bb25ee964345'}
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'TGF-f', 'id': 'TGF-f'})
Relation trouvée: {'head': 'GDF11', 'tail': 'TGF-f', 'type': 'causes', 'source': 'f16aa5a3d14c35c2752dcc9c943688188b48a65c301f158e4caf63b218dfa990'}
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'fibroblasts', 'id': 'fibroblasts'})
Relation trouvée: {'head': 'GDF11', 'tail': 'fibroblasts', 'type': 'causes', 'source': 'f16aa5a3d14c35c2752dcc9c943688188b48a65c301f158e4caf63b218dfa990'}
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'macrophages', 'id': 'macrophages'})
Relation trouvée: {'head': 'GDF11', 'tail': 'macrophages', 'type': 'causes', 'source': 'f16aa5a3d14c35c2752dcc9c943688188b48a65c301f158e4caf63b218dfa990'}
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'ADSC', 'id': 'ADSC'})
Relation trouvée: {'head': 'GDF11', 'tail': 'ADSC', 'type': 'causes', 'source': 'f16aa5a3d14c35c2752dcc9c943688188b48a65c301f158e4caf63b218dfa990'}
Processing combinations: ({'name': 'TGF-f', 'id': 'TGF-f'}, {'name': 'fibroblasts', 'id': 'fibroblasts'})
Relation trouvée: {'head': 'TGF-f', 'tail': 'fibroblasts', 'type': 'causes', 'source': 'f16aa5a3d14c35c2752dcc9c943688188b48a65c301f158e4caf63b218dfa990'}
Processing combinations: ({'name': 'TGF-f', 'id': 'TGF-f'}, {'name': 'macrophages', 'id': 'macrophages'})
Relation trouvée: {'head': 'TGF-f', 'tail': 'macrophages', 'type': 'causes', 'source': 'f16aa5a3d14c35c2752dcc9c943688188b48a65c301f158e4caf63b218dfa990'}
Processing combinations: ({'name': 'TGF-f', 'id': 'TGF-f'}, {'name': 'ADSC', 'id': 'ADSC'})
Relation trouvée: {'head': 'TGF-f', 'tail': 'ADSC', 'type': 'causes', 'source': 'f16aa5a3d14c35c2752dcc9c943688188b48a65c301f158e4caf63b218dfa990'}
Processing combinations: ({'name': 'fibroblasts', 'id': 'fibroblasts'}, {'name': 'macrophages', 'id': 'macrophages'})
Relation trouvée: {'head': 'fibroblasts', 'tail': 'macrophages', 'type': 'interacts', 'source': 'f16aa5a3d14c35c2752dcc9c943688188b48a65c301f158e4caf63b218dfa990'}
Processing combinations: ({'name': 'fibroblasts', 'id': 'fibroblasts'}, {'name': 'ADSC', 'id': 'ADSC'})
Relation trouvée: {'head': 'fibroblasts', 'tail': 'ADSC', 'type': 'causes', 'source': 'f16aa5a3d14c35c2752dcc9c943688188b48a65c301f158e4caf63b218dfa990'}
Processing combinations: ({'name': 'macrophages', 'id': 'macrophages'}, {'name': 'ADSC', 'id': 'ADSC'})
Relation trouvée: {'head': 'macrophages', 'tail': 'ADSC', 'type': 'causes', 'source': 'f16aa5a3d14c35c2752dcc9c943688188b48a65c301f158e4caf63b218dfa990'}
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'TFG', 'id': 'TFG'})
Erreur: The entity "TFG" is not in the text.
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'fibroblast', 'id': 'fibroblast'})
Relation trouvée: {'head': 'GDF11', 'tail': 'fibroblast', 'type': 'inhibits', 'source': 'e1c8d3434ba331e48b503d7a4af1833c1efc40783f7ee882b4ed7fe262d87c8a'}
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'skin cells', 'id': 'skin cells'})
Relation trouvée: {'head': 'GDF11', 'tail': 'skin cells', 'type': 'causes', 'source': 'e1c8d3434ba331e48b503d7a4af1833c1efc40783f7ee882b4ed7fe262d87c8a'}
Processing combinations: ({'name': 'TFG', 'id': 'TFG'}, {'name': 'fibroblast', 'id': 'fibroblast'})
Erreur: The entity "TFG" is not in the text.
Processing combinations: ({'name': 'TFG', 'id': 'TFG'}, {'name': 'skin cells', 'id': 'skin cells'})
Erreur: The entity "TFG" is not in the text.
Processing combinations: ({'name': 'fibroblast', 'id': 'fibroblast'}, {'name': 'skin cells', 'id': 'skin cells'})
Relation trouvée: {'head': 'fibroblast', 'tail': 'skin cells', 'type': 'inhibits', 'source': 'e1c8d3434ba331e48b503d7a4af1833c1efc40783f7ee882b4ed7fe262d87c8a'}
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'growth differentiation factor', 'id': 'growth differentiation factor'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'TGF-B', 'id': 'TGF-B'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'transforming growth factor', 'id': 'transforming growth factor'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'PDGF', 'id': 'PDGF'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'platelets derived growth factor', 'id': 'platelets derived growth factor'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'Il-1', 'id': 'Il-1'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'interleukin-1', 'id': 'interleukin-1'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'TNF-', 'id': 'TNF-'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'tumor necrosis factor-', 'id': 'tumor necrosis factor-'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'b-FGF', 'id': 'b-FGF'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'basic-fibroblast growth factor', 'id': 'basic-fibroblast growth factor'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'VEGF', 'id': 'VEGF'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'vascular endothelial growth factor', 'id': 'vascular endothelial growth factor'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'CXCR-4', 'id': 'CXCR-4'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'C motif chemokine receptor 4', 'id': 'C motif chemokine receptor 4'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'SDF-1', 'id': 'SDF-1'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'stromal derived factor-1', 'id': 'stromal derived factor-1'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'TLR2, 4', 'id': 'TLR2, 4'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'toll-like receptor2,4', 'id': 'toll-like receptor2,4'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'GM-CSF', 'id': 'GM-CSF'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'granulocyte monocyte-colony stimulating factor', 'id': 'granulocyte monocyte-colony stimulating factor'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'IGF', 'id': 'IGF'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'insulin growth factor', 'id': 'insulin growth factor'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'MMP-1,-2,', 'id': 'MMP-1,-2,'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': '-', 'id': '-'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'matrix metalloproteinase-1, -2, -9', 'id': 'matrix metalloproteinase-1, -2, -9'})
Erreur: The entity "GDF11" is not in the text.
Processing combinations: ({'name': 'growth differentiation factor', 'id': 'growth differentiation factor'}, {'name': 'TGF-B', 'id': 'TGF-B'})
Erreur: The entity "TGF-B" is not in the text.
Processing combinations: ({'name': 'growth differentiation factor', 'id': 'growth differentiation factor'}, {'name': 'transforming growth factor', 'id': 'transforming growth factor'})
Processing combinations: ({'name': 'growth differentiation factor', 'id': 'growth differentiation factor'}, {'name': 'PDGF', 'id': 'PDGF'})
Erreur: The entity "PDGF" is not in the text.
Processing combinations: ({'name': 'growth differentiation factor', 'id': 'growth differentiation factor'}, {'name': 'platelets derived growth factor', 'id': 'platelets derived growth factor'})
Processing combinations: ({'name': 'growth differentiation factor', 'id': 'growth differentiation factor'}, {'name': 'Il-1', 'id': 'Il-1'})
Erreur: The entity "Il-1" is not in the text.
Processing combinations: ({'name': 'growth differentiation factor', 'id': 'growth differentiation factor'}, {'name': 'interleukin-1', 'id': 'interleukin-1'})
Processing combinations: ({'name': 'growth differentiation factor', 'id': 'growth differentiation factor'}, {'name': 'TNF-', 'id': 'TNF-'})
Erreur: The entity "TNF-" is not in the text.
Processing combinations: ({'name': 'growth differentiation factor', 'id': 'growth differentiation factor'}, {'name': 'tumor necrosis factor-', 'id': 'tumor necrosis factor-'})
Processing combinations: ({'name': 'growth differentiation factor', 'id': 'growth differentiation factor'}, {'name': 'b-FGF', 'id': 'b-FGF'})
Erreur: The entity "b-FGF" is not in the text.
Processing combinations: ({'name': 'growth differentiation factor', 'id': 'growth differentiation factor'}, {'name': 'basic-fibroblast growth factor', 'id': 'basic-fibroblast growth factor'})
Processing combinations: ({'name': 'growth differentiation factor', 'id': 'growth differentiation factor'}, {'name': 'VEGF', 'id': 'VEGF'})
Erreur: The entity "VEGF" is not in the text.
Processing combinations: ({'name': 'growth differentiation factor', 'id': 'growth differentiation factor'}, {'name': 'vascular endothelial growth factor', 'id': 'vascular endothelial growth factor'})
Processing combinations: ({'name': 'growth differentiation factor', 'id': 'growth differentiation factor'}, {'name': 'CXCR-4', 'id': 'CXCR-4'})
Erreur: The entity "CXCR-4" is not in the text.
Processing combinations: ({'name': 'growth differentiation factor', 'id': 'growth differentiation factor'}, {'name': 'C motif chemokine receptor 4', 'id': 'C motif chemokine receptor 4'})
Processing combinations: ({'name': 'growth differentiation factor', 'id': 'growth differentiation factor'}, {'name': 'SDF-1', 'id': 'SDF-1'})
Erreur: The entity "SDF-1" is not in the text.
Processing combinations: ({'name': 'growth differentiation factor', 'id': 'growth differentiation factor'}, {'name': 'stromal derived factor-1', 'id': 'stromal derived factor-1'})
Processing combinations: ({'name': 'growth differentiation factor', 'id': 'growth differentiation factor'}, {'name': 'TLR2, 4', 'id': 'TLR2, 4'})
Erreur: The entity "TLR2, 4" is not in the text.
Processing combinations: ({'name': 'growth differentiation factor', 'id': 'growth differentiation factor'}, {'name': 'toll-like receptor2,4', 'id': 'toll-like receptor2,4'})
Erreur: The entity "toll-like receptor2,4" is not in the text.
Processing combinations: ({'name': 'growth differentiation factor', 'id': 'growth differentiation factor'}, {'name': 'GM-CSF', 'id': 'GM-CSF'})
Erreur: The entity "GM-CSF" is not in the text.
Processing combinations: ({'name': 'growth differentiation factor', 'id': 'growth differentiation factor'}, {'name': 'granulocyte monocyte-colony stimulating factor', 'id': 'granulocyte monocyte-colony stimulating factor'})
Processing combinations: ({'name': 'growth differentiation factor', 'id': 'growth differentiation factor'}, {'name': 'IGF', 'id': 'IGF'})
Erreur: The entity "IGF" is not in the text.
Processing combinations: ({'name': 'growth differentiation factor', 'id': 'growth differentiation factor'}, {'name': 'insulin growth factor', 'id': 'insulin growth factor'})
Processing combinations: ({'name': 'growth differentiation factor', 'id': 'growth differentiation factor'}, {'name': 'MMP-1,-2,', 'id': 'MMP-1,-2,'})
Erreur: The entity "MMP-1,-2," is not in the text.
Processing combinations: ({'name': 'growth differentiation factor', 'id': 'growth differentiation factor'}, {'name': '-', 'id': '-'})
Erreur: The entity "-" is not in the text.
Processing combinations: ({'name': 'growth differentiation factor', 'id': 'growth differentiation factor'}, {'name': 'matrix metalloproteinase-1, -2, -9', 'id': 'matrix metalloproteinase-1, -2, -9'})
Erreur: The entity "matrix metalloproteinase-1, -2, -9" is not in the text.
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'transforming growth factor', 'id': 'transforming growth factor'})
Erreur: The entity "TGF-B" is not in the text.
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'PDGF', 'id': 'PDGF'})
Erreur: The entity "TGF-B" is not in the text.
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'platelets derived growth factor', 'id': 'platelets derived growth factor'})
Erreur: The entity "TGF-B" is not in the text.
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'Il-1', 'id': 'Il-1'})
Erreur: The entity "TGF-B" is not in the text.
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'interleukin-1', 'id': 'interleukin-1'})
Erreur: The entity "TGF-B" is not in the text.
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'TNF-', 'id': 'TNF-'})
Erreur: The entity "TGF-B" is not in the text.
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'tumor necrosis factor-', 'id': 'tumor necrosis factor-'})
Erreur: The entity "TGF-B" is not in the text.
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'b-FGF', 'id': 'b-FGF'})
Erreur: The entity "TGF-B" is not in the text.
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'basic-fibroblast growth factor', 'id': 'basic-fibroblast growth factor'})
Erreur: The entity "TGF-B" is not in the text.
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'VEGF', 'id': 'VEGF'})
Erreur: The entity "TGF-B" is not in the text.
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'vascular endothelial growth factor', 'id': 'vascular endothelial growth factor'})
Erreur: The entity "TGF-B" is not in the text.
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'CXCR-4', 'id': 'CXCR-4'})
Erreur: The entity "TGF-B" is not in the text.
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'C motif chemokine receptor 4', 'id': 'C motif chemokine receptor 4'})
Erreur: The entity "TGF-B" is not in the text.
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'SDF-1', 'id': 'SDF-1'})
Erreur: The entity "TGF-B" is not in the text.
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'stromal derived factor-1', 'id': 'stromal derived factor-1'})
Erreur: The entity "TGF-B" is not in the text.
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'TLR2, 4', 'id': 'TLR2, 4'})
Erreur: The entity "TGF-B" is not in the text.
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'toll-like receptor2,4', 'id': 'toll-like receptor2,4'})
Erreur: The entity "TGF-B" is not in the text.
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'GM-CSF', 'id': 'GM-CSF'})
Erreur: The entity "TGF-B" is not in the text.
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'granulocyte monocyte-colony stimulating factor', 'id': 'granulocyte monocyte-colony stimulating factor'})
Erreur: The entity "TGF-B" is not in the text.
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'IGF', 'id': 'IGF'})
Erreur: The entity "TGF-B" is not in the text.
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'insulin growth factor', 'id': 'insulin growth factor'})
Erreur: The entity "TGF-B" is not in the text.
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'MMP-1,-2,', 'id': 'MMP-1,-2,'})
Erreur: The entity "TGF-B" is not in the text.
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': '-', 'id': '-'})
Erreur: The entity "TGF-B" is not in the text.
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'matrix metalloproteinase-1, -2, -9', 'id': 'matrix metalloproteinase-1, -2, -9'})
Erreur: The entity "TGF-B" is not in the text.
Processing combinations: ({'name': 'transforming growth factor', 'id': 'transforming growth factor'}, {'name': 'PDGF', 'id': 'PDGF'})
Erreur: The entity "PDGF" is not in the text.
Processing combinations: ({'name': 'transforming growth factor', 'id': 'transforming growth factor'}, {'name': 'platelets derived growth factor', 'id': 'platelets derived growth factor'})
Processing combinations: ({'name': 'transforming growth factor', 'id': 'transforming growth factor'}, {'name': 'Il-1', 'id': 'Il-1'})
Erreur: The entity "Il-1" is not in the text.
Processing combinations: ({'name': 'transforming growth factor', 'id': 'transforming growth factor'}, {'name': 'interleukin-1', 'id': 'interleukin-1'})
Processing combinations: ({'name': 'transforming growth factor', 'id': 'transforming growth factor'}, {'name': 'TNF-', 'id': 'TNF-'})
Erreur: The entity "TNF-" is not in the text.
Processing combinations: ({'name': 'transforming growth factor', 'id': 'transforming growth factor'}, {'name': 'tumor necrosis factor-', 'id': 'tumor necrosis factor-'})
Processing combinations: ({'name': 'transforming growth factor', 'id': 'transforming growth factor'}, {'name': 'b-FGF', 'id': 'b-FGF'})
Erreur: The entity "b-FGF" is not in the text.
Processing combinations: ({'name': 'transforming growth factor', 'id': 'transforming growth factor'}, {'name': 'basic-fibroblast growth factor', 'id': 'basic-fibroblast growth factor'})
Processing combinations: ({'name': 'transforming growth factor', 'id': 'transforming growth factor'}, {'name': 'VEGF', 'id': 'VEGF'})
Erreur: The entity "VEGF" is not in the text.
Processing combinations: ({'name': 'transforming growth factor', 'id': 'transforming growth factor'}, {'name': 'vascular endothelial growth factor', 'id': 'vascular endothelial growth factor'})
Processing combinations: ({'name': 'transforming growth factor', 'id': 'transforming growth factor'}, {'name': 'CXCR-4', 'id': 'CXCR-4'})
Erreur: The entity "CXCR-4" is not in the text.
Processing combinations: ({'name': 'transforming growth factor', 'id': 'transforming growth factor'}, {'name': 'C motif chemokine receptor 4', 'id': 'C motif chemokine receptor 4'})
Processing combinations: ({'name': 'transforming growth factor', 'id': 'transforming growth factor'}, {'name': 'SDF-1', 'id': 'SDF-1'})
Erreur: The entity "SDF-1" is not in the text.
Processing combinations: ({'name': 'transforming growth factor', 'id': 'transforming growth factor'}, {'name': 'stromal derived factor-1', 'id': 'stromal derived factor-1'})
Processing combinations: ({'name': 'transforming growth factor', 'id': 'transforming growth factor'}, {'name': 'TLR2, 4', 'id': 'TLR2, 4'})
Erreur: The entity "TLR2, 4" is not in the text.
Processing combinations: ({'name': 'transforming growth factor', 'id': 'transforming growth factor'}, {'name': 'toll-like receptor2,4', 'id': 'toll-like receptor2,4'})
Erreur: The entity "toll-like receptor2,4" is not in the text.
Processing combinations: ({'name': 'transforming growth factor', 'id': 'transforming growth factor'}, {'name': 'GM-CSF', 'id': 'GM-CSF'})
Erreur: The entity "GM-CSF" is not in the text.
Processing combinations: ({'name': 'transforming growth factor', 'id': 'transforming growth factor'}, {'name': 'granulocyte monocyte-colony stimulating factor', 'id': 'granulocyte monocyte-colony stimulating factor'})
Processing combinations: ({'name': 'transforming growth factor', 'id': 'transforming growth factor'}, {'name': 'IGF', 'id': 'IGF'})
Erreur: The entity "IGF" is not in the text.
Processing combinations: ({'name': 'transforming growth factor', 'id': 'transforming growth factor'}, {'name': 'insulin growth factor', 'id': 'insulin growth factor'})
Processing combinations: ({'name': 'transforming growth factor', 'id': 'transforming growth factor'}, {'name': 'MMP-1,-2,', 'id': 'MMP-1,-2,'})
Erreur: The entity "MMP-1,-2," is not in the text.
Processing combinations: ({'name': 'transforming growth factor', 'id': 'transforming growth factor'}, {'name': '-', 'id': '-'})
Erreur: The entity "-" is not in the text.
Processing combinations: ({'name': 'transforming growth factor', 'id': 'transforming growth factor'}, {'name': 'matrix metalloproteinase-1, -2, -9', 'id': 'matrix metalloproteinase-1, -2, -9'})
Erreur: The entity "matrix metalloproteinase-1, -2, -9" is not in the text.
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'platelets derived growth factor', 'id': 'platelets derived growth factor'})
Erreur: The entity "PDGF" is not in the text.
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'Il-1', 'id': 'Il-1'})
Erreur: The entity "PDGF" is not in the text.
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'interleukin-1', 'id': 'interleukin-1'})
Erreur: The entity "PDGF" is not in the text.
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'TNF-', 'id': 'TNF-'})
Erreur: The entity "PDGF" is not in the text.
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'tumor necrosis factor-', 'id': 'tumor necrosis factor-'})
Erreur: The entity "PDGF" is not in the text.
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'b-FGF', 'id': 'b-FGF'})
Erreur: The entity "PDGF" is not in the text.
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'basic-fibroblast growth factor', 'id': 'basic-fibroblast growth factor'})
Erreur: The entity "PDGF" is not in the text.
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'VEGF', 'id': 'VEGF'})
Erreur: The entity "PDGF" is not in the text.
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'vascular endothelial growth factor', 'id': 'vascular endothelial growth factor'})
Erreur: The entity "PDGF" is not in the text.
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'CXCR-4', 'id': 'CXCR-4'})
Erreur: The entity "PDGF" is not in the text.
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'C motif chemokine receptor 4', 'id': 'C motif chemokine receptor 4'})
Erreur: The entity "PDGF" is not in the text.
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'SDF-1', 'id': 'SDF-1'})
Erreur: The entity "PDGF" is not in the text.
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'stromal derived factor-1', 'id': 'stromal derived factor-1'})
Erreur: The entity "PDGF" is not in the text.
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'TLR2, 4', 'id': 'TLR2, 4'})
Erreur: The entity "PDGF" is not in the text.
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'toll-like receptor2,4', 'id': 'toll-like receptor2,4'})
Erreur: The entity "PDGF" is not in the text.
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Erreur: The entity "VEGF" is not in the text.
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Erreur: The entity "VEGF" is not in the text.
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'SDF-1', 'id': 'SDF-1'})
Erreur: The entity "VEGF" is not in the text.
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'stromal derived factor-1', 'id': 'stromal derived factor-1'})
Erreur: The entity "VEGF" is not in the text.
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'TLR2, 4', 'id': 'TLR2, 4'})
Erreur: The entity "VEGF" is not in the text.
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'toll-like receptor2,4', 'id': 'toll-like receptor2,4'})
Erreur: The entity "VEGF" is not in the text.
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'GM-CSF', 'id': 'GM-CSF'})
Erreur: The entity "VEGF" is not in the text.
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'granulocyte monocyte-colony stimulating factor', 'id': 'granulocyte monocyte-colony stimulating factor'})
Erreur: The entity "VEGF" is not in the text.
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'IGF', 'id': 'IGF'})
Erreur: The entity "VEGF" is not in the text.
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'insulin growth factor', 'id': 'insulin growth factor'})
Erreur: The entity "VEGF" is not in the text.
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'MMP-1,-2,', 'id': 'MMP-1,-2,'})
Erreur: The entity "VEGF" is not in the text.
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': '-', 'id': '-'})
Erreur: The entity "VEGF" is not in the text.
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'matrix metalloproteinase-1, -2, -9', 'id': 'matrix metalloproteinase-1, -2, -9'})
Erreur: The entity "VEGF" is not in the text.
Processing combinations: ({'name': 'vascular endothelial growth factor', 'id': 'vascular endothelial growth factor'}, {'name': 'CXCR-4', 'id': 'CXCR-4'})
Erreur: The entity "CXCR-4" is not in the text.
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Processing combinations: ({'name': 'vascular endothelial growth factor', 'id': 'vascular endothelial growth factor'}, {'name': 'SDF-1', 'id': 'SDF-1'})
Erreur: The entity "SDF-1" is not in the text.
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Processing combinations: ({'name': 'vascular endothelial growth factor', 'id': 'vascular endothelial growth factor'}, {'name': 'TLR2, 4', 'id': 'TLR2, 4'})
Erreur: The entity "TLR2, 4" is not in the text.
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Erreur: The entity "toll-like receptor2,4" is not in the text.
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Erreur: The entity "GM-CSF" is not in the text.
Processing combinations: ({'name': 'vascular endothelial growth factor', 'id': 'vascular endothelial growth factor'}, {'name': 'granulocyte monocyte-colony stimulating factor', 'id': 'granulocyte monocyte-colony stimulating factor'})
Processing combinations: ({'name': 'vascular endothelial growth factor', 'id': 'vascular endothelial growth factor'}, {'name': 'IGF', 'id': 'IGF'})
Erreur: The entity "IGF" is not in the text.
Processing combinations: ({'name': 'vascular endothelial growth factor', 'id': 'vascular endothelial growth factor'}, {'name': 'insulin growth factor', 'id': 'insulin growth factor'})
Processing combinations: ({'name': 'vascular endothelial growth factor', 'id': 'vascular endothelial growth factor'}, {'name': 'MMP-1,-2,', 'id': 'MMP-1,-2,'})
Erreur: The entity "MMP-1,-2," is not in the text.
Processing combinations: ({'name': 'vascular endothelial growth factor', 'id': 'vascular endothelial growth factor'}, {'name': '-', 'id': '-'})
Erreur: The entity "-" is not in the text.
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Erreur: The entity "matrix metalloproteinase-1, -2, -9" is not in the text.
Processing combinations: ({'name': 'CXCR-4', 'id': 'CXCR-4'}, {'name': 'C motif chemokine receptor 4', 'id': 'C motif chemokine receptor 4'})
Erreur: The entity "CXCR-4" is not in the text.
Processing combinations: ({'name': 'CXCR-4', 'id': 'CXCR-4'}, {'name': 'SDF-1', 'id': 'SDF-1'})
Erreur: The entity "CXCR-4" is not in the text.
Processing combinations: ({'name': 'CXCR-4', 'id': 'CXCR-4'}, {'name': 'stromal derived factor-1', 'id': 'stromal derived factor-1'})
Erreur: The entity "CXCR-4" is not in the text.
Processing combinations: ({'name': 'CXCR-4', 'id': 'CXCR-4'}, {'name': 'TLR2, 4', 'id': 'TLR2, 4'})
Erreur: The entity "CXCR-4" is not in the text.
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Erreur: The entity "CXCR-4" is not in the text.
Processing combinations: ({'name': 'CXCR-4', 'id': 'CXCR-4'}, {'name': 'GM-CSF', 'id': 'GM-CSF'})
Erreur: The entity "CXCR-4" is not in the text.
Processing combinations: ({'name': 'CXCR-4', 'id': 'CXCR-4'}, {'name': 'granulocyte monocyte-colony stimulating factor', 'id': 'granulocyte monocyte-colony stimulating factor'})
Erreur: The entity "CXCR-4" is not in the text.
Processing combinations: ({'name': 'CXCR-4', 'id': 'CXCR-4'}, {'name': 'IGF', 'id': 'IGF'})
Erreur: The entity "CXCR-4" is not in the text.
Processing combinations: ({'name': 'CXCR-4', 'id': 'CXCR-4'}, {'name': 'insulin growth factor', 'id': 'insulin growth factor'})
Erreur: The entity "CXCR-4" is not in the text.
Processing combinations: ({'name': 'CXCR-4', 'id': 'CXCR-4'}, {'name': 'MMP-1,-2,', 'id': 'MMP-1,-2,'})
Erreur: The entity "CXCR-4" is not in the text.
Processing combinations: ({'name': 'CXCR-4', 'id': 'CXCR-4'}, {'name': '-', 'id': '-'})
Erreur: The entity "CXCR-4" is not in the text.
Processing combinations: ({'name': 'CXCR-4', 'id': 'CXCR-4'}, {'name': 'matrix metalloproteinase-1, -2, -9', 'id': 'matrix metalloproteinase-1, -2, -9'})
Erreur: The entity "CXCR-4" is not in the text.
Processing combinations: ({'name': 'C motif chemokine receptor 4', 'id': 'C motif chemokine receptor 4'}, {'name': 'SDF-1', 'id': 'SDF-1'})
Erreur: The entity "SDF-1" is not in the text.
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Processing combinations: ({'name': 'C motif chemokine receptor 4', 'id': 'C motif chemokine receptor 4'}, {'name': 'TLR2, 4', 'id': 'TLR2, 4'})
Erreur: The entity "TLR2, 4" is not in the text.
Processing combinations: ({'name': 'C motif chemokine receptor 4', 'id': 'C motif chemokine receptor 4'}, {'name': 'toll-like receptor2,4', 'id': 'toll-like receptor2,4'})
Erreur: The entity "toll-like receptor2,4" is not in the text.
Processing combinations: ({'name': 'C motif chemokine receptor 4', 'id': 'C motif chemokine receptor 4'}, {'name': 'GM-CSF', 'id': 'GM-CSF'})
Erreur: The entity "GM-CSF" is not in the text.
Processing combinations: ({'name': 'C motif chemokine receptor 4', 'id': 'C motif chemokine receptor 4'}, {'name': 'granulocyte monocyte-colony stimulating factor', 'id': 'granulocyte monocyte-colony stimulating factor'})
Processing combinations: ({'name': 'C motif chemokine receptor 4', 'id': 'C motif chemokine receptor 4'}, {'name': 'IGF', 'id': 'IGF'})
Erreur: The entity "IGF" is not in the text.
Processing combinations: ({'name': 'C motif chemokine receptor 4', 'id': 'C motif chemokine receptor 4'}, {'name': 'insulin growth factor', 'id': 'insulin growth factor'})
Processing combinations: ({'name': 'C motif chemokine receptor 4', 'id': 'C motif chemokine receptor 4'}, {'name': 'MMP-1,-2,', 'id': 'MMP-1,-2,'})
Erreur: The entity "MMP-1,-2," is not in the text.
Processing combinations: ({'name': 'C motif chemokine receptor 4', 'id': 'C motif chemokine receptor 4'}, {'name': '-', 'id': '-'})
Erreur: The entity "-" is not in the text.
Processing combinations: ({'name': 'C motif chemokine receptor 4', 'id': 'C motif chemokine receptor 4'}, {'name': 'matrix metalloproteinase-1, -2, -9', 'id': 'matrix metalloproteinase-1, -2, -9'})
Erreur: The entity "matrix metalloproteinase-1, -2, -9" is not in the text.
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'stromal derived factor-1', 'id': 'stromal derived factor-1'})
Erreur: The entity "SDF-1" is not in the text.
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'TLR2, 4', 'id': 'TLR2, 4'})
Erreur: The entity "SDF-1" is not in the text.
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'toll-like receptor2,4', 'id': 'toll-like receptor2,4'})
Erreur: The entity "SDF-1" is not in the text.
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'GM-CSF', 'id': 'GM-CSF'})
Erreur: The entity "SDF-1" is not in the text.
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'granulocyte monocyte-colony stimulating factor', 'id': 'granulocyte monocyte-colony stimulating factor'})
Erreur: The entity "SDF-1" is not in the text.
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'IGF', 'id': 'IGF'})
Erreur: The entity "SDF-1" is not in the text.
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'insulin growth factor', 'id': 'insulin growth factor'})
Erreur: The entity "SDF-1" is not in the text.
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'MMP-1,-2,', 'id': 'MMP-1,-2,'})
Erreur: The entity "SDF-1" is not in the text.
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': '-', 'id': '-'})
Erreur: The entity "SDF-1" is not in the text.
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'matrix metalloproteinase-1, -2, -9', 'id': 'matrix metalloproteinase-1, -2, -9'})
Erreur: The entity "SDF-1" is not in the text.
Processing combinations: ({'name': 'stromal derived factor-1', 'id': 'stromal derived factor-1'}, {'name': 'TLR2, 4', 'id': 'TLR2, 4'})
Erreur: The entity "TLR2, 4" is not in the text.
Processing combinations: ({'name': 'stromal derived factor-1', 'id': 'stromal derived factor-1'}, {'name': 'toll-like receptor2,4', 'id': 'toll-like receptor2,4'})
Erreur: The entity "toll-like receptor2,4" is not in the text.
Processing combinations: ({'name': 'stromal derived factor-1', 'id': 'stromal derived factor-1'}, {'name': 'GM-CSF', 'id': 'GM-CSF'})
Erreur: The entity "GM-CSF" is not in the text.
Processing combinations: ({'name': 'stromal derived factor-1', 'id': 'stromal derived factor-1'}, {'name': 'granulocyte monocyte-colony stimulating factor', 'id': 'granulocyte monocyte-colony stimulating factor'})
Processing combinations: ({'name': 'stromal derived factor-1', 'id': 'stromal derived factor-1'}, {'name': 'IGF', 'id': 'IGF'})
Erreur: The entity "IGF" is not in the text.
Processing combinations: ({'name': 'stromal derived factor-1', 'id': 'stromal derived factor-1'}, {'name': 'insulin growth factor', 'id': 'insulin growth factor'})
Processing combinations: ({'name': 'stromal derived factor-1', 'id': 'stromal derived factor-1'}, {'name': 'MMP-1,-2,', 'id': 'MMP-1,-2,'})
Erreur: The entity "MMP-1,-2," is not in the text.
Processing combinations: ({'name': 'stromal derived factor-1', 'id': 'stromal derived factor-1'}, {'name': '-', 'id': '-'})
Erreur: The entity "-" is not in the text.
Processing combinations: ({'name': 'stromal derived factor-1', 'id': 'stromal derived factor-1'}, {'name': 'matrix metalloproteinase-1, -2, -9', 'id': 'matrix metalloproteinase-1, -2, -9'})
Erreur: The entity "matrix metalloproteinase-1, -2, -9" is not in the text.
Processing combinations: ({'name': 'TLR2, 4', 'id': 'TLR2, 4'}, {'name': 'toll-like receptor2,4', 'id': 'toll-like receptor2,4'})
Erreur: The entity "TLR2, 4" is not in the text.
Processing combinations: ({'name': 'TLR2, 4', 'id': 'TLR2, 4'}, {'name': 'GM-CSF', 'id': 'GM-CSF'})
Erreur: The entity "TLR2, 4" is not in the text.
Processing combinations: ({'name': 'TLR2, 4', 'id': 'TLR2, 4'}, {'name': 'granulocyte monocyte-colony stimulating factor', 'id': 'granulocyte monocyte-colony stimulating factor'})
Erreur: The entity "TLR2, 4" is not in the text.
Processing combinations: ({'name': 'TLR2, 4', 'id': 'TLR2, 4'}, {'name': 'IGF', 'id': 'IGF'})
Erreur: The entity "TLR2, 4" is not in the text.
Processing combinations: ({'name': 'TLR2, 4', 'id': 'TLR2, 4'}, {'name': 'insulin growth factor', 'id': 'insulin growth factor'})
Erreur: The entity "TLR2, 4" is not in the text.
Processing combinations: ({'name': 'TLR2, 4', 'id': 'TLR2, 4'}, {'name': 'MMP-1,-2,', 'id': 'MMP-1,-2,'})
Erreur: The entity "TLR2, 4" is not in the text.
Processing combinations: ({'name': 'TLR2, 4', 'id': 'TLR2, 4'}, {'name': '-', 'id': '-'})
Erreur: The entity "TLR2, 4" is not in the text.
Processing combinations: ({'name': 'TLR2, 4', 'id': 'TLR2, 4'}, {'name': 'matrix metalloproteinase-1, -2, -9', 'id': 'matrix metalloproteinase-1, -2, -9'})
Erreur: The entity "TLR2, 4" is not in the text.
Processing combinations: ({'name': 'toll-like receptor2,4', 'id': 'toll-like receptor2,4'}, {'name': 'GM-CSF', 'id': 'GM-CSF'})
Erreur: The entity "toll-like receptor2,4" is not in the text.
Processing combinations: ({'name': 'toll-like receptor2,4', 'id': 'toll-like receptor2,4'}, {'name': 'granulocyte monocyte-colony stimulating factor', 'id': 'granulocyte monocyte-colony stimulating factor'})
Erreur: The entity "toll-like receptor2,4" is not in the text.
Processing combinations: ({'name': 'toll-like receptor2,4', 'id': 'toll-like receptor2,4'}, {'name': 'IGF', 'id': 'IGF'})
Erreur: The entity "toll-like receptor2,4" is not in the text.
Processing combinations: ({'name': 'toll-like receptor2,4', 'id': 'toll-like receptor2,4'}, {'name': 'insulin growth factor', 'id': 'insulin growth factor'})
Erreur: The entity "toll-like receptor2,4" is not in the text.
Processing combinations: ({'name': 'toll-like receptor2,4', 'id': 'toll-like receptor2,4'}, {'name': 'MMP-1,-2,', 'id': 'MMP-1,-2,'})
Erreur: The entity "toll-like receptor2,4" is not in the text.
Processing combinations: ({'name': 'toll-like receptor2,4', 'id': 'toll-like receptor2,4'}, {'name': '-', 'id': '-'})
Erreur: The entity "toll-like receptor2,4" is not in the text.
Processing combinations: ({'name': 'toll-like receptor2,4', 'id': 'toll-like receptor2,4'}, {'name': 'matrix metalloproteinase-1, -2, -9', 'id': 'matrix metalloproteinase-1, -2, -9'})
Erreur: The entity "toll-like receptor2,4" is not in the text.
Processing combinations: ({'name': 'GM-CSF', 'id': 'GM-CSF'}, {'name': 'granulocyte monocyte-colony stimulating factor', 'id': 'granulocyte monocyte-colony stimulating factor'})
Erreur: The entity "GM-CSF" is not in the text.
Processing combinations: ({'name': 'GM-CSF', 'id': 'GM-CSF'}, {'name': 'IGF', 'id': 'IGF'})
Erreur: The entity "GM-CSF" is not in the text.
Processing combinations: ({'name': 'GM-CSF', 'id': 'GM-CSF'}, {'name': 'insulin growth factor', 'id': 'insulin growth factor'})
Erreur: The entity "GM-CSF" is not in the text.
Processing combinations: ({'name': 'GM-CSF', 'id': 'GM-CSF'}, {'name': 'MMP-1,-2,', 'id': 'MMP-1,-2,'})
Erreur: The entity "GM-CSF" is not in the text.
Processing combinations: ({'name': 'GM-CSF', 'id': 'GM-CSF'}, {'name': '-', 'id': '-'})
Erreur: The entity "GM-CSF" is not in the text.
Processing combinations: ({'name': 'GM-CSF', 'id': 'GM-CSF'}, {'name': 'matrix metalloproteinase-1, -2, -9', 'id': 'matrix metalloproteinase-1, -2, -9'})
Erreur: The entity "GM-CSF" is not in the text.
Processing combinations: ({'name': 'granulocyte monocyte-colony stimulating factor', 'id': 'granulocyte monocyte-colony stimulating factor'}, {'name': 'IGF', 'id': 'IGF'})
Erreur: The entity "IGF" is not in the text.
Processing combinations: ({'name': 'granulocyte monocyte-colony stimulating factor', 'id': 'granulocyte monocyte-colony stimulating factor'}, {'name': 'insulin growth factor', 'id': 'insulin growth factor'})
Processing combinations: ({'name': 'granulocyte monocyte-colony stimulating factor', 'id': 'granulocyte monocyte-colony stimulating factor'}, {'name': 'MMP-1,-2,', 'id': 'MMP-1,-2,'})
Erreur: The entity "MMP-1,-2," is not in the text.
Processing combinations: ({'name': 'granulocyte monocyte-colony stimulating factor', 'id': 'granulocyte monocyte-colony stimulating factor'}, {'name': '-', 'id': '-'})
Erreur: The entity "-" is not in the text.
Processing combinations: ({'name': 'granulocyte monocyte-colony stimulating factor', 'id': 'granulocyte monocyte-colony stimulating factor'}, {'name': 'matrix metalloproteinase-1, -2, -9', 'id': 'matrix metalloproteinase-1, -2, -9'})
Erreur: The entity "matrix metalloproteinase-1, -2, -9" is not in the text.
Processing combinations: ({'name': 'IGF', 'id': 'IGF'}, {'name': 'insulin growth factor', 'id': 'insulin growth factor'})
Erreur: The entity "IGF" is not in the text.
Processing combinations: ({'name': 'IGF', 'id': 'IGF'}, {'name': 'MMP-1,-2,', 'id': 'MMP-1,-2,'})
Erreur: The entity "IGF" is not in the text.
Processing combinations: ({'name': 'IGF', 'id': 'IGF'}, {'name': '-', 'id': '-'})
Erreur: The entity "IGF" is not in the text.
Processing combinations: ({'name': 'IGF', 'id': 'IGF'}, {'name': 'matrix metalloproteinase-1, -2, -9', 'id': 'matrix metalloproteinase-1, -2, -9'})
Erreur: The entity "IGF" is not in the text.
Processing combinations: ({'name': 'insulin growth factor', 'id': 'insulin growth factor'}, {'name': 'MMP-1,-2,', 'id': 'MMP-1,-2,'})
Erreur: The entity "MMP-1,-2," is not in the text.
Processing combinations: ({'name': 'insulin growth factor', 'id': 'insulin growth factor'}, {'name': '-', 'id': '-'})
Erreur: The entity "-" is not in the text.
Processing combinations: ({'name': 'insulin growth factor', 'id': 'insulin growth factor'}, {'name': 'matrix metalloproteinase-1, -2, -9', 'id': 'matrix metalloproteinase-1, -2, -9'})
Erreur: The entity "matrix metalloproteinase-1, -2, -9" is not in the text.
Processing combinations: ({'name': 'MMP-1,-2,', 'id': 'MMP-1,-2,'}, {'name': '-', 'id': '-'})
Erreur: The entity "MMP-1,-2," is not in the text.
Processing combinations: ({'name': 'MMP-1,-2,', 'id': 'MMP-1,-2,'}, {'name': 'matrix metalloproteinase-1, -2, -9', 'id': 'matrix metalloproteinase-1, -2, -9'})
Erreur: The entity "MMP-1,-2," is not in the text.
Processing combinations: ({'name': '-', 'id': '-'}, {'name': 'matrix metalloproteinase-1, -2, -9', 'id': 'matrix metalloproteinase-1, -2, -9'})
Erreur: The entity "-" is not in the text.
Processing combinations: ({'name': 'senescent cells', 'id': 'senescent cells'}, {'name': 'IL-6', 'id': 'IL-6'})
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Processing combinations: ({'name': 'senescent cells', 'id': 'senescent cells'}, {'name': 'IL-8', 'id': 'IL-8'})
Relation trouvée: {'head': 'senescent cells', 'tail': 'IL-8', 'type': 'causes', 'source': '6e0792af04408574bb3cbfd42673deffdee4f1569eb9d3a75b557449abfe45d9'}
Processing combinations: ({'name': 'senescent cells', 'id': 'senescent cells'}, {'name': 'TNF-,', 'id': 'TNF-,'})
Erreur: The entity "TNF-," is not in the text.
Processing combinations: ({'name': 'senescent cells', 'id': 'senescent cells'}, {'name': 'chronic inflammation', 'id': 'chronic inflammation'})
Erreur: The entity "chronic inflammation" is not in the text.
Processing combinations: ({'name': 'IL-6', 'id': 'IL-6'}, {'name': 'IL-8', 'id': 'IL-8'})
Relation trouvée: {'head': 'IL-6', 'tail': 'IL-8', 'type': 'causes', 'source': '6e0792af04408574bb3cbfd42673deffdee4f1569eb9d3a75b557449abfe45d9'}
Processing combinations: ({'name': 'IL-6', 'id': 'IL-6'}, {'name': 'TNF-,', 'id': 'TNF-,'})
Erreur: The entity "TNF-," is not in the text.
Processing combinations: ({'name': 'IL-6', 'id': 'IL-6'}, {'name': 'chronic inflammation', 'id': 'chronic inflammation'})
Erreur: The entity "chronic inflammation" is not in the text.
Processing combinations: ({'name': 'IL-8', 'id': 'IL-8'}, {'name': 'TNF-,', 'id': 'TNF-,'})
Erreur: The entity "TNF-," is not in the text.
Processing combinations: ({'name': 'IL-8', 'id': 'IL-8'}, {'name': 'chronic inflammation', 'id': 'chronic inflammation'})
Erreur: The entity "chronic inflammation" is not in the text.
Processing combinations: ({'name': 'TNF-,', 'id': 'TNF-,'}, {'name': 'chronic inflammation', 'id': 'chronic inflammation'})
Erreur: The entity "TNF-," is not in the text.
Processing combinations: ({'name': 'IL-B', 'id': 'IL-B'}, {'name': 'inflammatory-aging', 'id': 'inflammatory-aging'})
Relation trouvée: {'head': 'IL-B', 'tail': 'inflammatory-aging', 'type': 'inhibits', 'source': 'b027359b7787caa25af925d06f5d53796560712e8ef1ec1f35e565e6c10045b6'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'TGF-B', 'id': 'TGF-B'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'TGF-B', 'type': 'inhibits', 'source': 'addd4a9107203285810ec54c2ce939e7e17f4694c05ce1960669b51007cbf408'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'IL-18', 'id': 'IL-18'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'IL-18', 'type': 'inhibits', 'source': 'addd4a9107203285810ec54c2ce939e7e17f4694c05ce1960669b51007cbf408'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'IL-6', 'id': 'IL-6'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'IL-6', 'type': 'inhibits', 'source': 'addd4a9107203285810ec54c2ce939e7e17f4694c05ce1960669b51007cbf408'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'macrophage', 'id': 'macrophage'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'macrophage', 'type': 'inhibits', 'source': 'addd4a9107203285810ec54c2ce939e7e17f4694c05ce1960669b51007cbf408'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'M1', 'id': 'M1'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'M1', 'type': 'inhibits', 'source': 'addd4a9107203285810ec54c2ce939e7e17f4694c05ce1960669b51007cbf408'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'M2', 'id': 'M2'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'M2', 'type': 'inhibits', 'source': 'addd4a9107203285810ec54c2ce939e7e17f4694c05ce1960669b51007cbf408'}
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'IL-18', 'id': 'IL-18'})
Relation trouvée: {'head': 'TGF-B', 'tail': 'IL-18', 'type': 'inhibits', 'source': 'addd4a9107203285810ec54c2ce939e7e17f4694c05ce1960669b51007cbf408'}
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'IL-6', 'id': 'IL-6'})
Relation trouvée: {'head': 'TGF-B', 'tail': 'IL-6', 'type': 'inhibits', 'source': 'addd4a9107203285810ec54c2ce939e7e17f4694c05ce1960669b51007cbf408'}
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'macrophage', 'id': 'macrophage'})
Relation trouvée: {'head': 'TGF-B', 'tail': 'macrophage', 'type': 'inhibits', 'source': 'addd4a9107203285810ec54c2ce939e7e17f4694c05ce1960669b51007cbf408'}
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'M1', 'id': 'M1'})
Relation trouvée: {'head': 'TGF-B', 'tail': 'M1', 'type': 'inhibits', 'source': 'addd4a9107203285810ec54c2ce939e7e17f4694c05ce1960669b51007cbf408'}
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'M2', 'id': 'M2'})
Relation trouvée: {'head': 'TGF-B', 'tail': 'M2', 'type': 'inhibits', 'source': 'addd4a9107203285810ec54c2ce939e7e17f4694c05ce1960669b51007cbf408'}
Processing combinations: ({'name': 'IL-18', 'id': 'IL-18'}, {'name': 'IL-6', 'id': 'IL-6'})
Relation trouvée: {'head': 'IL-18', 'tail': 'IL-6', 'type': 'inhibits', 'source': 'addd4a9107203285810ec54c2ce939e7e17f4694c05ce1960669b51007cbf408'}
Processing combinations: ({'name': 'IL-18', 'id': 'IL-18'}, {'name': 'macrophage', 'id': 'macrophage'})
Relation trouvée: {'head': 'IL-18', 'tail': 'macrophage', 'type': 'inhibits', 'source': 'addd4a9107203285810ec54c2ce939e7e17f4694c05ce1960669b51007cbf408'}
Processing combinations: ({'name': 'IL-18', 'id': 'IL-18'}, {'name': 'M1', 'id': 'M1'})
Relation trouvée: {'head': 'IL-18', 'tail': 'M1', 'type': 'inhibits', 'source': 'addd4a9107203285810ec54c2ce939e7e17f4694c05ce1960669b51007cbf408'}
Processing combinations: ({'name': 'IL-18', 'id': 'IL-18'}, {'name': 'M2', 'id': 'M2'})
Relation trouvée: {'head': 'IL-18', 'tail': 'M2', 'type': 'inhibits', 'source': 'addd4a9107203285810ec54c2ce939e7e17f4694c05ce1960669b51007cbf408'}
Processing combinations: ({'name': 'IL-6', 'id': 'IL-6'}, {'name': 'macrophage', 'id': 'macrophage'})
Relation trouvée: {'head': 'IL-6', 'tail': 'macrophage', 'type': 'inhibits', 'source': 'addd4a9107203285810ec54c2ce939e7e17f4694c05ce1960669b51007cbf408'}
Processing combinations: ({'name': 'IL-6', 'id': 'IL-6'}, {'name': 'M1', 'id': 'M1'})
Relation trouvée: {'head': 'IL-6', 'tail': 'M1', 'type': 'inhibits', 'source': 'addd4a9107203285810ec54c2ce939e7e17f4694c05ce1960669b51007cbf408'}
Processing combinations: ({'name': 'IL-6', 'id': 'IL-6'}, {'name': 'M2', 'id': 'M2'})
Relation trouvée: {'head': 'IL-6', 'tail': 'M2', 'type': 'inhibits', 'source': 'addd4a9107203285810ec54c2ce939e7e17f4694c05ce1960669b51007cbf408'}
Processing combinations: ({'name': 'macrophage', 'id': 'macrophage'}, {'name': 'M1', 'id': 'M1'})
Relation trouvée: {'head': 'macrophage', 'tail': 'M1', 'type': 'inhibits', 'source': 'addd4a9107203285810ec54c2ce939e7e17f4694c05ce1960669b51007cbf408'}
Processing combinations: ({'name': 'macrophage', 'id': 'macrophage'}, {'name': 'M2', 'id': 'M2'})
Relation trouvée: {'head': 'macrophage', 'tail': 'M2', 'type': 'inhibits', 'source': 'addd4a9107203285810ec54c2ce939e7e17f4694c05ce1960669b51007cbf408'}
Processing combinations: ({'name': 'M1', 'id': 'M1'}, {'name': 'M2', 'id': 'M2'})
Relation trouvée: {'head': 'M1', 'tail': 'M2', 'type': 'inhibits', 'source': 'addd4a9107203285810ec54c2ce939e7e17f4694c05ce1960669b51007cbf408'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'macrophages', 'id': 'macrophages'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'macrophages', 'type': 'inhibits', 'source': 'df488e16dfe213b424438cec48a9f603fe21d02903b57f5b16c128a619040e33'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'TNF', 'id': 'TNF'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'TNF', 'type': 'inhibits', 'source': 'df488e16dfe213b424438cec48a9f603fe21d02903b57f5b16c128a619040e33'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'IL-10', 'id': 'IL-10'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'IL-10', 'type': 'inhibits', 'source': 'df488e16dfe213b424438cec48a9f603fe21d02903b57f5b16c128a619040e33'}
Processing combinations: ({'name': 'macrophages', 'id': 'macrophages'}, {'name': 'TNF', 'id': 'TNF'})
Relation trouvée: {'head': 'macrophages', 'tail': 'TNF', 'type': 'inhibits', 'source': 'df488e16dfe213b424438cec48a9f603fe21d02903b57f5b16c128a619040e33'}
Processing combinations: ({'name': 'macrophages', 'id': 'macrophages'}, {'name': 'IL-10', 'id': 'IL-10'})
Relation trouvée: {'head': 'macrophages', 'tail': 'IL-10', 'type': 'inhibits', 'source': 'df488e16dfe213b424438cec48a9f603fe21d02903b57f5b16c128a619040e33'}
Processing combinations: ({'name': 'TNF', 'id': 'TNF'}, {'name': 'IL-10', 'id': 'IL-10'})
Relation trouvée: {'head': 'TNF', 'tail': 'IL-10', 'type': 'inhibits', 'source': 'df488e16dfe213b424438cec48a9f603fe21d02903b57f5b16c128a619040e33'}
Processing combinations: ({'name': 'dermal cells', 'id': 'dermal cells'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Erreur: The entity "ADSCs" is not in the text.
Processing combinations: ({'name': 'burns', 'id': 'burns'}, {'name': 'rat', 'id': 'rat'})
Processing combinations: ({'name': 'burns', 'id': 'burns'}, {'name': 'CD68', 'id': 'CD68'})
Erreur: The entity "CD68" is not in the text.
Processing combinations: ({'name': 'burns', 'id': 'burns'}, {'name': 'nitric oxide', 'id': 'nitric oxide'})
Processing combinations: ({'name': 'burns', 'id': 'burns'}, {'name': 'nitric oxide synthase', 'id': 'nitric oxide synthase'})
Erreur: The entity "nitric oxide synthase" is not in the text.
Processing combinations: ({'name': 'burns', 'id': 'burns'}, {'name': 'iNOS', 'id': 'iNOS'})
Erreur: The entity "iNOS" is not in the text.
Processing combinations: ({'name': 'burns', 'id': 'burns'}, {'name': 'DESS', 'id': 'DESS'})
Relation trouvée: {'head': 'burns', 'tail': 'DESS', 'type': 'inhibits', 'source': '156b9c44c94348daf1f551c5c44bb10f57f545be91f581ca3aac4884a5850840'}
Processing combinations: ({'name': 'burns', 'id': 'burns'}, {'name': 'CD68', 'id': 'CD68'})
Erreur: The entity "CD68" is not in the text.
Processing combinations: ({'name': 'burns', 'id': 'burns'}, {'name': 'CD206+ M2 macrophages', 'id': 'CD206+ M2 macrophages'})
Relation trouvée: {'head': 'burns', 'tail': 'CD206+ M2 macrophages', 'type': 'inhibits', 'source': '156b9c44c94348daf1f551c5c44bb10f57f545be91f581ca3aac4884a5850840'}
Processing combinations: ({'name': 'burns', 'id': 'burns'}, {'name': 'CD206', 'id': 'CD206'})
Erreur: The entity "CD206" is not in the text.
Processing combinations: ({'name': 'burns', 'id': 'burns'}, {'name': 'M2 macrophages', 'id': 'M2 macrophages'})
Relation trouvée: {'head': 'burns', 'tail': 'M2 macrophages', 'type': 'inhibits', 'source': '156b9c44c94348daf1f551c5c44bb10f57f545be91f581ca3aac4884a5850840'}
Processing combinations: ({'name': 'rat', 'id': 'rat'}, {'name': 'CD68', 'id': 'CD68'})
Erreur: The entity "CD68" is not in the text.
Processing combinations: ({'name': 'rat', 'id': 'rat'}, {'name': 'nitric oxide', 'id': 'nitric oxide'})
Processing combinations: ({'name': 'rat', 'id': 'rat'}, {'name': 'nitric oxide synthase', 'id': 'nitric oxide synthase'})
Erreur: The entity "nitric oxide synthase" is not in the text.
Processing combinations: ({'name': 'rat', 'id': 'rat'}, {'name': 'iNOS', 'id': 'iNOS'})
Erreur: The entity "iNOS" is not in the text.
Processing combinations: ({'name': 'rat', 'id': 'rat'}, {'name': 'DESS', 'id': 'DESS'})
Relation trouvée: {'head': 'rat', 'tail': 'DESS', 'type': 'treats', 'source': '156b9c44c94348daf1f551c5c44bb10f57f545be91f581ca3aac4884a5850840'}
Processing combinations: ({'name': 'rat', 'id': 'rat'}, {'name': 'CD68', 'id': 'CD68'})
Erreur: The entity "CD68" is not in the text.
Processing combinations: ({'name': 'rat', 'id': 'rat'}, {'name': 'CD206+ M2 macrophages', 'id': 'CD206+ M2 macrophages'})
Relation trouvée: {'head': 'rat', 'tail': 'CD206+ M2 macrophages', 'type': 'associated', 'source': '156b9c44c94348daf1f551c5c44bb10f57f545be91f581ca3aac4884a5850840'}
Processing combinations: ({'name': 'rat', 'id': 'rat'}, {'name': 'CD206', 'id': 'CD206'})
Erreur: The entity "CD206" is not in the text.
Processing combinations: ({'name': 'rat', 'id': 'rat'}, {'name': 'M2 macrophages', 'id': 'M2 macrophages'})
Relation trouvée: {'head': 'rat', 'tail': 'M2 macrophages', 'type': 'associated', 'source': '156b9c44c94348daf1f551c5c44bb10f57f545be91f581ca3aac4884a5850840'}
Processing combinations: ({'name': 'CD68', 'id': 'CD68'}, {'name': 'nitric oxide', 'id': 'nitric oxide'})
Erreur: The entity "CD68" is not in the text.
Processing combinations: ({'name': 'CD68', 'id': 'CD68'}, {'name': 'nitric oxide synthase', 'id': 'nitric oxide synthase'})
Erreur: The entity "CD68" is not in the text.
Processing combinations: ({'name': 'CD68', 'id': 'CD68'}, {'name': 'iNOS', 'id': 'iNOS'})
Erreur: The entity "CD68" is not in the text.
Processing combinations: ({'name': 'CD68', 'id': 'CD68'}, {'name': 'DESS', 'id': 'DESS'})
Erreur: The entity "CD68" is not in the text.
Processing combinations: ({'name': 'CD68', 'id': 'CD68'}, {'name': 'CD68', 'id': 'CD68'})
Erreur: The entity "CD68" is not in the text.
Processing combinations: ({'name': 'CD68', 'id': 'CD68'}, {'name': 'CD206+ M2 macrophages', 'id': 'CD206+ M2 macrophages'})
Erreur: The entity "CD68" is not in the text.
Processing combinations: ({'name': 'CD68', 'id': 'CD68'}, {'name': 'CD206', 'id': 'CD206'})
Erreur: The entity "CD68" is not in the text.
Processing combinations: ({'name': 'CD68', 'id': 'CD68'}, {'name': 'M2 macrophages', 'id': 'M2 macrophages'})
Erreur: The entity "CD68" is not in the text.
Processing combinations: ({'name': 'nitric oxide', 'id': 'nitric oxide'}, {'name': 'nitric oxide synthase', 'id': 'nitric oxide synthase'})
Erreur: The entity "nitric oxide synthase" is not in the text.
Processing combinations: ({'name': 'nitric oxide', 'id': 'nitric oxide'}, {'name': 'iNOS', 'id': 'iNOS'})
Erreur: The entity "iNOS" is not in the text.
Processing combinations: ({'name': 'nitric oxide', 'id': 'nitric oxide'}, {'name': 'DESS', 'id': 'DESS'})
Relation trouvée: {'head': 'nitric oxide', 'tail': 'DESS', 'type': 'inhibits', 'source': '156b9c44c94348daf1f551c5c44bb10f57f545be91f581ca3aac4884a5850840'}
Processing combinations: ({'name': 'nitric oxide', 'id': 'nitric oxide'}, {'name': 'CD68', 'id': 'CD68'})
Erreur: The entity "CD68" is not in the text.
Processing combinations: ({'name': 'nitric oxide', 'id': 'nitric oxide'}, {'name': 'CD206+ M2 macrophages', 'id': 'CD206+ M2 macrophages'})
Relation trouvée: {'head': 'nitric oxide', 'tail': 'CD206+ M2 macrophages', 'type': 'inhibits', 'source': '156b9c44c94348daf1f551c5c44bb10f57f545be91f581ca3aac4884a5850840'}
Processing combinations: ({'name': 'nitric oxide', 'id': 'nitric oxide'}, {'name': 'CD206', 'id': 'CD206'})
Erreur: The entity "CD206" is not in the text.
Processing combinations: ({'name': 'nitric oxide', 'id': 'nitric oxide'}, {'name': 'M2 macrophages', 'id': 'M2 macrophages'})
Relation trouvée: {'head': 'nitric oxide', 'tail': 'M2 macrophages', 'type': 'inhibits', 'source': '156b9c44c94348daf1f551c5c44bb10f57f545be91f581ca3aac4884a5850840'}
Processing combinations: ({'name': 'nitric oxide synthase', 'id': 'nitric oxide synthase'}, {'name': 'iNOS', 'id': 'iNOS'})
Erreur: The entity "nitric oxide synthase" is not in the text.
Processing combinations: ({'name': 'nitric oxide synthase', 'id': 'nitric oxide synthase'}, {'name': 'DESS', 'id': 'DESS'})
Erreur: The entity "nitric oxide synthase" is not in the text.
Processing combinations: ({'name': 'nitric oxide synthase', 'id': 'nitric oxide synthase'}, {'name': 'CD68', 'id': 'CD68'})
Erreur: The entity "nitric oxide synthase" is not in the text.
Processing combinations: ({'name': 'nitric oxide synthase', 'id': 'nitric oxide synthase'}, {'name': 'CD206+ M2 macrophages', 'id': 'CD206+ M2 macrophages'})
Erreur: The entity "nitric oxide synthase" is not in the text.
Processing combinations: ({'name': 'nitric oxide synthase', 'id': 'nitric oxide synthase'}, {'name': 'CD206', 'id': 'CD206'})
Erreur: The entity "nitric oxide synthase" is not in the text.
Processing combinations: ({'name': 'nitric oxide synthase', 'id': 'nitric oxide synthase'}, {'name': 'M2 macrophages', 'id': 'M2 macrophages'})
Erreur: The entity "nitric oxide synthase" is not in the text.
Processing combinations: ({'name': 'iNOS', 'id': 'iNOS'}, {'name': 'DESS', 'id': 'DESS'})
Erreur: The entity "iNOS" is not in the text.
Processing combinations: ({'name': 'iNOS', 'id': 'iNOS'}, {'name': 'CD68', 'id': 'CD68'})
Erreur: The entity "iNOS" is not in the text.
Processing combinations: ({'name': 'iNOS', 'id': 'iNOS'}, {'name': 'CD206+ M2 macrophages', 'id': 'CD206+ M2 macrophages'})
Erreur: The entity "iNOS" is not in the text.
Processing combinations: ({'name': 'iNOS', 'id': 'iNOS'}, {'name': 'CD206', 'id': 'CD206'})
Erreur: The entity "iNOS" is not in the text.
Processing combinations: ({'name': 'iNOS', 'id': 'iNOS'}, {'name': 'M2 macrophages', 'id': 'M2 macrophages'})
Erreur: The entity "iNOS" is not in the text.
Processing combinations: ({'name': 'DESS', 'id': 'DESS'}, {'name': 'CD68', 'id': 'CD68'})
Erreur: The entity "CD68" is not in the text.
Processing combinations: ({'name': 'DESS', 'id': 'DESS'}, {'name': 'CD206+ M2 macrophages', 'id': 'CD206+ M2 macrophages'})
Relation trouvée: {'head': 'DESS', 'tail': 'CD206+ M2 macrophages', 'type': 'inhibits', 'source': '156b9c44c94348daf1f551c5c44bb10f57f545be91f581ca3aac4884a5850840'}
Processing combinations: ({'name': 'DESS', 'id': 'DESS'}, {'name': 'CD206', 'id': 'CD206'})
Erreur: The entity "CD206" is not in the text.
Processing combinations: ({'name': 'DESS', 'id': 'DESS'}, {'name': 'M2 macrophages', 'id': 'M2 macrophages'})
Relation trouvée: {'head': 'DESS', 'tail': 'M2 macrophages', 'type': 'inhibits', 'source': '156b9c44c94348daf1f551c5c44bb10f57f545be91f581ca3aac4884a5850840'}
Processing combinations: ({'name': 'CD68', 'id': 'CD68'}, {'name': 'CD206+ M2 macrophages', 'id': 'CD206+ M2 macrophages'})
Erreur: The entity "CD68" is not in the text.
Processing combinations: ({'name': 'CD68', 'id': 'CD68'}, {'name': 'CD206', 'id': 'CD206'})
Erreur: The entity "CD68" is not in the text.
Processing combinations: ({'name': 'CD68', 'id': 'CD68'}, {'name': 'M2 macrophages', 'id': 'M2 macrophages'})
Erreur: The entity "CD68" is not in the text.
Processing combinations: ({'name': 'CD206+ M2 macrophages', 'id': 'CD206+ M2 macrophages'}, {'name': 'CD206', 'id': 'CD206'})
Erreur: The entity "CD206" is not in the text.
Processing combinations: ({'name': 'CD206+ M2 macrophages', 'id': 'CD206+ M2 macrophages'}, {'name': 'M2 macrophages', 'id': 'M2 macrophages'})
Relation trouvée: {'head': 'CD206+ M2 macrophages', 'tail': 'M2 macrophages', 'type': 'inhibits', 'source': '156b9c44c94348daf1f551c5c44bb10f57f545be91f581ca3aac4884a5850840'}
Processing combinations: ({'name': 'CD206', 'id': 'CD206'}, {'name': 'M2 macrophages', 'id': 'M2 macrophages'})
Erreur: The entity "CD206" is not in the text.
Processing combinations: ({'name': 'monocytes', 'id': 'monocytes'}, {'name': 'macrophages', 'id': 'macrophages'})
Erreur: The entity "monocytes" is not in the text.
Processing combinations: ({'name': 'monocytes', 'id': 'monocytes'}, {'name': 'CD11b', 'id': 'CD11b'})
Erreur: The entity "monocytes" is not in the text.
Processing combinations: ({'name': 'monocytes', 'id': 'monocytes'}, {'name': 'CD68', 'id': 'CD68'})
Erreur: The entity "monocytes" is not in the text.
Processing combinations: ({'name': 'monocytes', 'id': 'monocytes'}, {'name': 'endothelial cells', 'id': 'endothelial cells'})
Erreur: The entity "monocytes" is not in the text.
Processing combinations: ({'name': 'macrophages', 'id': 'macrophages'}, {'name': 'CD11b', 'id': 'CD11b'})
Erreur: The entity "macrophages" is not in the text.
Processing combinations: ({'name': 'macrophages', 'id': 'macrophages'}, {'name': 'CD68', 'id': 'CD68'})
Erreur: The entity "macrophages" is not in the text.
Processing combinations: ({'name': 'macrophages', 'id': 'macrophages'}, {'name': 'endothelial cells', 'id': 'endothelial cells'})
Erreur: The entity "macrophages" is not in the text.
Processing combinations: ({'name': 'CD11b', 'id': 'CD11b'}, {'name': 'CD68', 'id': 'CD68'})
Erreur: The entity "CD11b" is not in the text.
Processing combinations: ({'name': 'CD11b', 'id': 'CD11b'}, {'name': 'endothelial cells', 'id': 'endothelial cells'})
Erreur: The entity "CD11b" is not in the text.
Processing combinations: ({'name': 'CD68', 'id': 'CD68'}, {'name': 'endothelial cells', 'id': 'endothelial cells'})
Erreur: The entity "CD68" is not in the text.
Processing combinations: ({'name': 'endothelial cells', 'id': 'endothelial cells'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Relation trouvée: {'head': 'endothelial cells', 'tail': 'ADSCs', 'type': 'interacts', 'source': '43c46066ab48236a1cde41fa5ff0b8997c2c9227e63b6747c8e100de98955cae'}
Processing combinations: ({'name': 'endothelial cells', 'id': 'endothelial cells'}, {'name': 'IL-6', 'id': 'IL-6'})
Relation trouvée: {'head': 'endothelial cells', 'tail': 'IL-6', 'type': 'interacts', 'source': '43c46066ab48236a1cde41fa5ff0b8997c2c9227e63b6747c8e100de98955cae'}
Processing combinations: ({'name': 'endothelial cells', 'id': 'endothelial cells'}, {'name': 'IL-8', 'id': 'IL-8'})
Relation trouvée: {'head': 'endothelial cells', 'tail': 'IL-8', 'type': 'interacts', 'source': '43c46066ab48236a1cde41fa5ff0b8997c2c9227e63b6747c8e100de98955cae'}
Processing combinations: ({'name': 'endothelial cells', 'id': 'endothelial cells'}, {'name': 'MCP-1', 'id': 'MCP-1'})
Relation trouvée: {'head': 'endothelial cells', 'tail': 'MCP-1', 'type': 'associated', 'source': '43c46066ab48236a1cde41fa5ff0b8997c2c9227e63b6747c8e100de98955cae'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'IL-6', 'id': 'IL-6'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'IL-6', 'type': 'interacts', 'source': '43c46066ab48236a1cde41fa5ff0b8997c2c9227e63b6747c8e100de98955cae'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'IL-8', 'id': 'IL-8'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'IL-8', 'type': 'interacts', 'source': '43c46066ab48236a1cde41fa5ff0b8997c2c9227e63b6747c8e100de98955cae'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'MCP-1', 'id': 'MCP-1'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'MCP-1', 'type': 'interacts', 'source': '43c46066ab48236a1cde41fa5ff0b8997c2c9227e63b6747c8e100de98955cae'}
Processing combinations: ({'name': 'IL-6', 'id': 'IL-6'}, {'name': 'IL-8', 'id': 'IL-8'})
Processing combinations: ({'name': 'IL-6', 'id': 'IL-6'}, {'name': 'MCP-1', 'id': 'MCP-1'})
Relation trouvée: {'head': 'IL-6', 'tail': 'MCP-1', 'type': 'interacts', 'source': '43c46066ab48236a1cde41fa5ff0b8997c2c9227e63b6747c8e100de98955cae'}
Processing combinations: ({'name': 'IL-8', 'id': 'IL-8'}, {'name': 'MCP-1', 'id': 'MCP-1'})
Relation trouvée: {'head': 'IL-8', 'tail': 'MCP-1', 'type': 'interacts', 'source': '43c46066ab48236a1cde41fa5ff0b8997c2c9227e63b6747c8e100de98955cae'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'DF', 'id': 'DF'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'DF', 'type': 'interacts', 'source': 'e7826f8a24c177c642d7473b1fe54b288b85b7fd01abb439b41e9705e69e3f1a'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'senescent cells', 'id': 'senescent cells'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'senescent cells', 'type': 'interacts', 'source': 'e7826f8a24c177c642d7473b1fe54b288b85b7fd01abb439b41e9705e69e3f1a'}
Processing combinations: ({'name': 'DF', 'id': 'DF'}, {'name': 'senescent cells', 'id': 'senescent cells'})
Relation trouvée: {'head': 'DF', 'tail': 'senescent cells', 'type': 'interacts', 'source': 'e7826f8a24c177c642d7473b1fe54b288b85b7fd01abb439b41e9705e69e3f1a'}
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'human skin cell', 'id': 'human skin cell'})
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'human', 'id': 'human'})
Processing combinations: ({'name': 'human skin cell', 'id': 'human skin cell'}, {'name': 'human', 'id': 'human'})
Processing combinations: ({'name': 'human', 'id': 'human'}, {'name': 'skin disorders', 'id': 'skin disorders'})
Relation trouvée: {'head': 'human', 'tail': 'skin disorders', 'type': 'causes', 'source': 'd6be2967bf32614c5df4c043eb453953c563db6c865088b9ff17a831e04cb1ff'}
Processing combinations: ({'name': 'human', 'id': 'human'}, {'name': 'psoriasis', 'id': 'psoriasis'})
Relation trouvée: {'head': 'human', 'tail': 'psoriasis', 'type': 'treats', 'source': 'd6be2967bf32614c5df4c043eb453953c563db6c865088b9ff17a831e04cb1ff'}
Processing combinations: ({'name': 'human', 'id': 'human'}, {'name': 'basal cell carcinoma', 'id': 'basal cell carcinoma'})
Relation trouvée: {'head': 'human', 'tail': 'basal cell carcinoma', 'type': 'causes', 'source': 'd6be2967bf32614c5df4c043eb453953c563db6c865088b9ff17a831e04cb1ff'}
Processing combinations: ({'name': 'human', 'id': 'human'}, {'name': 'squamous cell carcinoma', 'id': 'squamous cell carcinoma'})
Erreur: The entity "squamous cell carcinoma" is not in the text.
Processing combinations: ({'name': 'skin disorders', 'id': 'skin disorders'}, {'name': 'psoriasis', 'id': 'psoriasis'})
Relation trouvée: {'head': 'skin disorders', 'tail': 'psoriasis', 'type': 'treats', 'source': 'd6be2967bf32614c5df4c043eb453953c563db6c865088b9ff17a831e04cb1ff'}
Processing combinations: ({'name': 'skin disorders', 'id': 'skin disorders'}, {'name': 'basal cell carcinoma', 'id': 'basal cell carcinoma'})
Relation trouvée: {'head': 'skin disorders', 'tail': 'basal cell carcinoma', 'type': 'causes', 'source': 'd6be2967bf32614c5df4c043eb453953c563db6c865088b9ff17a831e04cb1ff'}
Processing combinations: ({'name': 'skin disorders', 'id': 'skin disorders'}, {'name': 'squamous cell carcinoma', 'id': 'squamous cell carcinoma'})
Erreur: The entity "squamous cell carcinoma" is not in the text.
Processing combinations: ({'name': 'psoriasis', 'id': 'psoriasis'}, {'name': 'basal cell carcinoma', 'id': 'basal cell carcinoma'})
Relation trouvée: {'head': 'psoriasis', 'tail': 'basal cell carcinoma', 'type': 'causes', 'source': 'd6be2967bf32614c5df4c043eb453953c563db6c865088b9ff17a831e04cb1ff'}
Processing combinations: ({'name': 'psoriasis', 'id': 'psoriasis'}, {'name': 'squamous cell carcinoma', 'id': 'squamous cell carcinoma'})
Erreur: The entity "squamous cell carcinoma" is not in the text.
Processing combinations: ({'name': 'basal cell carcinoma', 'id': 'basal cell carcinoma'}, {'name': 'squamous cell carcinoma', 'id': 'squamous cell carcinoma'})
Erreur: The entity "squamous cell carcinoma" is not in the text.
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'heat shock protein 47', 'id': 'heat shock protein 47'})
Relation trouvée: {'head': 'SDF-1', 'tail': 'heat shock protein 47', 'type': 'inhibits', 'source': '5c5e6865fada2349b0ad2b14bc261470ef28b024c79aef33aacd35454f4e9804'}
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'HSP47', 'id': 'HSP47'})
Erreur: The entity "HSP47" is not in the text.
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'fibroblasts', 'id': 'fibroblasts'})
Processing combinations: ({'name': 'heat shock protein 47', 'id': 'heat shock protein 47'}, {'name': 'HSP47', 'id': 'HSP47'})
Erreur: The entity "HSP47" is not in the text.
Processing combinations: ({'name': 'heat shock protein 47', 'id': 'heat shock protein 47'}, {'name': 'fibroblasts', 'id': 'fibroblasts'})
Processing combinations: ({'name': 'HSP47', 'id': 'HSP47'}, {'name': 'fibroblasts', 'id': 'fibroblasts'})
Erreur: The entity "HSP47" is not in the text.
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'SDF-1', 'id': 'SDF-1'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'SDF-1', 'type': 'inhibits', 'source': 'e35975cefc6703478ca142cf1f3ab20070548927e15668144ea1ba9b20f425f1'}
Processing combinations: ({'name': 'fibroblasts', 'id': 'fibroblasts'}, {'name': 'CD44', 'id': 'CD44'})
Relation trouvée: {'head': 'fibroblasts', 'tail': 'CD44', 'type': 'treats', 'source': '0908028a0117bfc5974f7d0a1b8fbf7c7d2332207426f4a1de23f7222f89263d'}
Processing combinations: ({'name': 'fibroblasts', 'id': 'fibroblasts'}, {'name': 'N-cadherin', 'id': 'N-cadherin'})
Relation trouvée: {'head': 'fibroblasts', 'tail': 'N-cadherin', 'type': 'treats', 'source': '0908028a0117bfc5974f7d0a1b8fbf7c7d2332207426f4a1de23f7222f89263d'}
Processing combinations: ({'name': 'CD44', 'id': 'CD44'}, {'name': 'N-cadherin', 'id': 'N-cadherin'})
Relation trouvée: {'head': 'CD44', 'tail': 'N-cadherin', 'type': 'inhibits', 'source': '0908028a0117bfc5974f7d0a1b8fbf7c7d2332207426f4a1de23f7222f89263d'}
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'keratinocytes', 'id': 'keratinocytes'})
Relation trouvée: {'head': 'SDF-1', 'tail': 'keratinocytes', 'type': 'associated', 'source': '9d74f1dedc0f96276f16a6067564f80322e8d2346bb0f52de54d76243258aa5a'}
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'CXCR-4', 'id': 'CXCR-4'})
Relation trouvée: {'head': 'SDF-1', 'tail': 'CXCR-4', 'type': 'interacts', 'source': '9d74f1dedc0f96276f16a6067564f80322e8d2346bb0f52de54d76243258aa5a'}
Processing combinations: ({'name': 'keratinocytes', 'id': 'keratinocytes'}, {'name': 'CXCR-4', 'id': 'CXCR-4'})
Relation trouvée: {'head': 'keratinocytes', 'tail': 'CXCR-4', 'type': 'interacts', 'source': '9d74f1dedc0f96276f16a6067564f80322e8d2346bb0f52de54d76243258aa5a'}
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'CXCR-4', 'id': 'CXCR-4'})
Erreur: The entity "SDF-1" is not in the text.
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'cancer', 'id': 'cancer'})
Erreur: The entity "SDF-1" is not in the text.
Processing combinations: ({'name': 'CXCR-4', 'id': 'CXCR-4'}, {'name': 'cancer', 'id': 'cancer'})
Erreur: The entity "CXCR-4" is not in the text.
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'PDGF', 'id': 'PDGF'})
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'IGF', 'id': 'IGF'})
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'HGF', 'id': 'HGF'})
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'b-FGF', 'id': 'b-FGF'})
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'SDF-1', 'id': 'SDF-1'})
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'TGF-B', 'id': 'TGF-B'})
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'GDF11', 'id': 'GDF11'})
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Relation trouvée: {'head': 'VEGF', 'tail': 'ADSCs', 'type': 'inhibits', 'source': '77d2b95ac6135f27974bd44d92c64f0e245894bbc0630537dac534d5f5aabf62'}
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'DF', 'id': 'DF'})
Relation trouvée: {'head': 'VEGF', 'tail': 'DF', 'type': 'inhibits', 'source': '77d2b95ac6135f27974bd44d92c64f0e245894bbc0630537dac534d5f5aabf62'}
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'endothelial cells', 'id': 'endothelial cells'})
Relation trouvée: {'head': 'VEGF', 'tail': 'endothelial cells', 'type': 'treats', 'source': '77d2b95ac6135f27974bd44d92c64f0e245894bbc0630537dac534d5f5aabf62'}
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'IGF', 'id': 'IGF'})
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'HGF', 'id': 'HGF'})
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'b-FGF', 'id': 'b-FGF'})
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'SDF-1', 'id': 'SDF-1'})
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'TGF-B', 'id': 'TGF-B'})
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'GDF11', 'id': 'GDF11'})
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'DF', 'id': 'DF'})
Relation trouvée: {'head': 'PDGF', 'tail': 'DF', 'type': 'inhibits', 'source': '77d2b95ac6135f27974bd44d92c64f0e245894bbc0630537dac534d5f5aabf62'}
Processing combinations: ({'name': 'PDGF', 'id': 'PDGF'}, {'name': 'endothelial cells', 'id': 'endothelial cells'})
Relation trouvée: {'head': 'PDGF', 'tail': 'endothelial cells', 'type': 'treats', 'source': '77d2b95ac6135f27974bd44d92c64f0e245894bbc0630537dac534d5f5aabf62'}
Processing combinations: ({'name': 'IGF', 'id': 'IGF'}, {'name': 'HGF', 'id': 'HGF'})
Processing combinations: ({'name': 'IGF', 'id': 'IGF'}, {'name': 'b-FGF', 'id': 'b-FGF'})
Processing combinations: ({'name': 'IGF', 'id': 'IGF'}, {'name': 'SDF-1', 'id': 'SDF-1'})
Processing combinations: ({'name': 'IGF', 'id': 'IGF'}, {'name': 'TGF-B', 'id': 'TGF-B'})
Processing combinations: ({'name': 'IGF', 'id': 'IGF'}, {'name': 'GDF11', 'id': 'GDF11'})
Processing combinations: ({'name': 'IGF', 'id': 'IGF'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'IGF', 'id': 'IGF'}, {'name': 'DF', 'id': 'DF'})
Relation trouvée: {'head': 'IGF', 'tail': 'DF', 'type': 'inhibits', 'source': '77d2b95ac6135f27974bd44d92c64f0e245894bbc0630537dac534d5f5aabf62'}
Processing combinations: ({'name': 'IGF', 'id': 'IGF'}, {'name': 'endothelial cells', 'id': 'endothelial cells'})
Processing combinations: ({'name': 'HGF', 'id': 'HGF'}, {'name': 'b-FGF', 'id': 'b-FGF'})
Processing combinations: ({'name': 'HGF', 'id': 'HGF'}, {'name': 'SDF-1', 'id': 'SDF-1'})
Processing combinations: ({'name': 'HGF', 'id': 'HGF'}, {'name': 'TGF-B', 'id': 'TGF-B'})
Processing combinations: ({'name': 'HGF', 'id': 'HGF'}, {'name': 'GDF11', 'id': 'GDF11'})
Processing combinations: ({'name': 'HGF', 'id': 'HGF'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'HGF', 'id': 'HGF'}, {'name': 'DF', 'id': 'DF'})
Relation trouvée: {'head': 'HGF', 'tail': 'DF', 'type': 'inhibits', 'source': '77d2b95ac6135f27974bd44d92c64f0e245894bbc0630537dac534d5f5aabf62'}
Processing combinations: ({'name': 'HGF', 'id': 'HGF'}, {'name': 'endothelial cells', 'id': 'endothelial cells'})
Processing combinations: ({'name': 'b-FGF', 'id': 'b-FGF'}, {'name': 'SDF-1', 'id': 'SDF-1'})
Processing combinations: ({'name': 'b-FGF', 'id': 'b-FGF'}, {'name': 'TGF-B', 'id': 'TGF-B'})
Processing combinations: ({'name': 'b-FGF', 'id': 'b-FGF'}, {'name': 'GDF11', 'id': 'GDF11'})
Processing combinations: ({'name': 'b-FGF', 'id': 'b-FGF'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'b-FGF', 'id': 'b-FGF'}, {'name': 'DF', 'id': 'DF'})
Relation trouvée: {'head': 'b-FGF', 'tail': 'DF', 'type': 'inhibits', 'source': '77d2b95ac6135f27974bd44d92c64f0e245894bbc0630537dac534d5f5aabf62'}
Processing combinations: ({'name': 'b-FGF', 'id': 'b-FGF'}, {'name': 'endothelial cells', 'id': 'endothelial cells'})
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'TGF-B', 'id': 'TGF-B'})
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'GDF11', 'id': 'GDF11'})
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Relation trouvée: {'head': 'SDF-1', 'tail': 'ADSCs', 'type': 'inhibits', 'source': '77d2b95ac6135f27974bd44d92c64f0e245894bbc0630537dac534d5f5aabf62'}
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'DF', 'id': 'DF'})
Relation trouvée: {'head': 'SDF-1', 'tail': 'DF', 'type': 'inhibits', 'source': '77d2b95ac6135f27974bd44d92c64f0e245894bbc0630537dac534d5f5aabf62'}
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'endothelial cells', 'id': 'endothelial cells'})
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'GDF11', 'id': 'GDF11'})
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Relation trouvée: {'head': 'TGF-B', 'tail': 'ADSCs', 'type': 'inhibits', 'source': '77d2b95ac6135f27974bd44d92c64f0e245894bbc0630537dac534d5f5aabf62'}
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'DF', 'id': 'DF'})
Relation trouvée: {'head': 'TGF-B', 'tail': 'DF', 'type': 'inhibits', 'source': '77d2b95ac6135f27974bd44d92c64f0e245894bbc0630537dac534d5f5aabf62'}
Processing combinations: ({'name': 'TGF-B', 'id': 'TGF-B'}, {'name': 'endothelial cells', 'id': 'endothelial cells'})
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Relation trouvée: {'head': 'GDF11', 'tail': 'ADSCs', 'type': 'inhibits', 'source': '77d2b95ac6135f27974bd44d92c64f0e245894bbc0630537dac534d5f5aabf62'}
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'DF', 'id': 'DF'})
Relation trouvée: {'head': 'GDF11', 'tail': 'DF', 'type': 'inhibits', 'source': '77d2b95ac6135f27974bd44d92c64f0e245894bbc0630537dac534d5f5aabf62'}
Processing combinations: ({'name': 'GDF11', 'id': 'GDF11'}, {'name': 'endothelial cells', 'id': 'endothelial cells'})
Relation trouvée: {'head': 'GDF11', 'tail': 'endothelial cells', 'type': 'treats', 'source': '77d2b95ac6135f27974bd44d92c64f0e245894bbc0630537dac534d5f5aabf62'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'DF', 'id': 'DF'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'DF', 'type': 'inhibits', 'source': '77d2b95ac6135f27974bd44d92c64f0e245894bbc0630537dac534d5f5aabf62'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'endothelial cells', 'id': 'endothelial cells'})
Processing combinations: ({'name': 'DF', 'id': 'DF'}, {'name': 'endothelial cells', 'id': 'endothelial cells'})
Relation trouvée: {'head': 'DF', 'tail': 'endothelial cells', 'type': 'treats', 'source': '77d2b95ac6135f27974bd44d92c64f0e245894bbc0630537dac534d5f5aabf62'}
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'DF', 'id': 'DF'})
Relation trouvée: {'head': 'SDF-1', 'tail': 'DF', 'type': 'inhibits', 'source': 'cb5490bd0a3ff505f42acec94e4bb88618d19b2f7a2502d542abcf4809beb29e'}
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'keratinocyte', 'id': 'keratinocyte'})
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'ADSC', 'id': 'ADSC'})
Relation trouvée: {'head': 'SDF-1', 'tail': 'ADSC', 'type': 'inhibits', 'source': 'cb5490bd0a3ff505f42acec94e4bb88618d19b2f7a2502d542abcf4809beb29e'}
Processing combinations: ({'name': 'DF', 'id': 'DF'}, {'name': 'keratinocyte', 'id': 'keratinocyte'})
Processing combinations: ({'name': 'DF', 'id': 'DF'}, {'name': 'ADSC', 'id': 'ADSC'})
Relation trouvée: {'head': 'DF', 'tail': 'ADSC', 'type': 'interacts', 'source': 'cb5490bd0a3ff505f42acec94e4bb88618d19b2f7a2502d542abcf4809beb29e'}
Processing combinations: ({'name': 'keratinocyte', 'id': 'keratinocyte'}, {'name': 'ADSC', 'id': 'ADSC'})
Relation trouvée: {'head': 'keratinocyte', 'tail': 'ADSC', 'type': 'interacts', 'source': 'cb5490bd0a3ff505f42acec94e4bb88618d19b2f7a2502d542abcf4809beb29e'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'wound', 'id': 'wound'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'wound', 'type': 'inhibits', 'source': 'b997b2323ce092cd7b8f34ad74617b33eca82837b34ed5de000598b58375e523'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'ADSCs', 'type': 'inhibits', 'source': 'b997b2323ce092cd7b8f34ad74617b33eca82837b34ed5de000598b58375e523'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'endothelial progenitor cells', 'id': 'endothelial progenitor cells'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'endothelial progenitor cells', 'type': 'treats', 'source': 'b997b2323ce092cd7b8f34ad74617b33eca82837b34ed5de000598b58375e523'}
Processing combinations: ({'name': 'wound', 'id': 'wound'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Relation trouvée: {'head': 'wound', 'tail': 'ADSCs', 'type': 'inhibits', 'source': 'b997b2323ce092cd7b8f34ad74617b33eca82837b34ed5de000598b58375e523'}
Processing combinations: ({'name': 'wound', 'id': 'wound'}, {'name': 'endothelial progenitor cells', 'id': 'endothelial progenitor cells'})
Relation trouvée: {'head': 'wound', 'tail': 'endothelial progenitor cells', 'type': 'treats', 'source': 'b997b2323ce092cd7b8f34ad74617b33eca82837b34ed5de000598b58375e523'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'endothelial progenitor cells', 'id': 'endothelial progenitor cells'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'endothelial progenitor cells', 'type': 'treats', 'source': 'b997b2323ce092cd7b8f34ad74617b33eca82837b34ed5de000598b58375e523'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'endothelial cells', 'id': 'endothelial cells'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'endothelial cells', 'type': 'interacts', 'source': '5a03a85a48511e6e4ce69b2326d67f96a236ca26e57cc9a58e6bdd167cb283bc'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'macrophages', 'id': 'macrophages'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'macrophages', 'type': 'interacts', 'source': '5a03a85a48511e6e4ce69b2326d67f96a236ca26e57cc9a58e6bdd167cb283bc'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'MCP-1', 'id': 'MCP-1'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'MCP-1', 'type': 'inhibits', 'source': '5a03a85a48511e6e4ce69b2326d67f96a236ca26e57cc9a58e6bdd167cb283bc'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'VEGF', 'id': 'VEGF'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'VEGF', 'type': 'inhibits', 'source': '5a03a85a48511e6e4ce69b2326d67f96a236ca26e57cc9a58e6bdd167cb283bc'}
Processing combinations: ({'name': 'endothelial cells', 'id': 'endothelial cells'}, {'name': 'macrophages', 'id': 'macrophages'})
Relation trouvée: {'head': 'endothelial cells', 'tail': 'macrophages', 'type': 'interacts', 'source': '5a03a85a48511e6e4ce69b2326d67f96a236ca26e57cc9a58e6bdd167cb283bc'}
Processing combinations: ({'name': 'endothelial cells', 'id': 'endothelial cells'}, {'name': 'MCP-1', 'id': 'MCP-1'})
Relation trouvée: {'head': 'endothelial cells', 'tail': 'MCP-1', 'type': 'interacts', 'source': '5a03a85a48511e6e4ce69b2326d67f96a236ca26e57cc9a58e6bdd167cb283bc'}
Processing combinations: ({'name': 'endothelial cells', 'id': 'endothelial cells'}, {'name': 'VEGF', 'id': 'VEGF'})
Relation trouvée: {'head': 'endothelial cells', 'tail': 'VEGF', 'type': 'interacts', 'source': '5a03a85a48511e6e4ce69b2326d67f96a236ca26e57cc9a58e6bdd167cb283bc'}
Processing combinations: ({'name': 'macrophages', 'id': 'macrophages'}, {'name': 'MCP-1', 'id': 'MCP-1'})
Relation trouvée: {'head': 'macrophages', 'tail': 'MCP-1', 'type': 'interacts', 'source': '5a03a85a48511e6e4ce69b2326d67f96a236ca26e57cc9a58e6bdd167cb283bc'}
Processing combinations: ({'name': 'macrophages', 'id': 'macrophages'}, {'name': 'VEGF', 'id': 'VEGF'})
Relation trouvée: {'head': 'macrophages', 'tail': 'VEGF', 'type': 'interacts', 'source': '5a03a85a48511e6e4ce69b2326d67f96a236ca26e57cc9a58e6bdd167cb283bc'}
Processing combinations: ({'name': 'MCP-1', 'id': 'MCP-1'}, {'name': 'VEGF', 'id': 'VEGF'})
Relation trouvée: {'head': 'MCP-1', 'tail': 'VEGF', 'type': 'inhibits', 'source': '5a03a85a48511e6e4ce69b2326d67f96a236ca26e57cc9a58e6bdd167cb283bc'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'DFs', 'id': 'DFs'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'DFs', 'type': 'interacts', 'source': 'b38ad47f480c093e272987a2e506b87ea67b2a2b1587c3aef4edc5278fa806af'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'macrophages', 'id': 'macrophages'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'macrophages', 'type': 'interacts', 'source': 'b38ad47f480c093e272987a2e506b87ea67b2a2b1587c3aef4edc5278fa806af'}
Processing combinations: ({'name': 'DFs', 'id': 'DFs'}, {'name': 'macrophages', 'id': 'macrophages'})
Relation trouvée: {'head': 'DFs', 'tail': 'macrophages', 'type': 'interacts', 'source': 'b38ad47f480c093e272987a2e506b87ea67b2a2b1587c3aef4edc5278fa806af'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'HIF-1', 'id': 'HIF-1'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'HIF-1', 'type': 'inhibits', 'source': '244d9f3cd272a03404cfae2dac6cb4b19d8b11413c6a1b524fa7e472fe45d7e5'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'VEGF gene', 'id': 'VEGF gene'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'VEGF gene', 'type': 'inhibits', 'source': '244d9f3cd272a03404cfae2dac6cb4b19d8b11413c6a1b524fa7e472fe45d7e5'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'endothelial cells', 'id': 'endothelial cells'})
Processing combinations: ({'name': 'HIF-1', 'id': 'HIF-1'}, {'name': 'VEGF gene', 'id': 'VEGF gene'})
Relation trouvée: {'head': 'HIF-1', 'tail': 'VEGF gene', 'type': 'inhibits', 'source': '244d9f3cd272a03404cfae2dac6cb4b19d8b11413c6a1b524fa7e472fe45d7e5'}
Processing combinations: ({'name': 'HIF-1', 'id': 'HIF-1'}, {'name': 'endothelial cells', 'id': 'endothelial cells'})
Processing combinations: ({'name': 'VEGF gene', 'id': 'VEGF gene'}, {'name': 'endothelial cells', 'id': 'endothelial cells'})
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'keratinocytes', 'id': 'keratinocytes'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'keratinocytes', 'type': 'inhibits', 'source': '2a7b5395dd30bb1ab01ab866c06221f93f0d937c611156deffd1017a67602283'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'HIF-1a', 'id': 'HIF-1a'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'HIF-1a', 'type': 'inhibits', 'source': '2a7b5395dd30bb1ab01ab866c06221f93f0d937c611156deffd1017a67602283'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'VEGF', 'id': 'VEGF'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'VEGF', 'type': 'inhibits', 'source': '2a7b5395dd30bb1ab01ab866c06221f93f0d937c611156deffd1017a67602283'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'MMP', 'id': 'MMP'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'MMP', 'type': 'inhibits', 'source': '2a7b5395dd30bb1ab01ab866c06221f93f0d937c611156deffd1017a67602283'}
Processing combinations: ({'name': 'keratinocytes', 'id': 'keratinocytes'}, {'name': 'HIF-1a', 'id': 'HIF-1a'})
Relation trouvée: {'head': 'keratinocytes', 'tail': 'HIF-1a', 'type': 'inhibits', 'source': '2a7b5395dd30bb1ab01ab866c06221f93f0d937c611156deffd1017a67602283'}
Processing combinations: ({'name': 'keratinocytes', 'id': 'keratinocytes'}, {'name': 'VEGF', 'id': 'VEGF'})
Relation trouvée: {'head': 'keratinocytes', 'tail': 'VEGF', 'type': 'inhibits', 'source': '2a7b5395dd30bb1ab01ab866c06221f93f0d937c611156deffd1017a67602283'}
Processing combinations: ({'name': 'keratinocytes', 'id': 'keratinocytes'}, {'name': 'MMP', 'id': 'MMP'})
Relation trouvée: {'head': 'keratinocytes', 'tail': 'MMP', 'type': 'associated', 'source': '2a7b5395dd30bb1ab01ab866c06221f93f0d937c611156deffd1017a67602283'}
Processing combinations: ({'name': 'HIF-1a', 'id': 'HIF-1a'}, {'name': 'VEGF', 'id': 'VEGF'})
Relation trouvée: {'head': 'HIF-1a', 'tail': 'VEGF', 'type': 'inhibits', 'source': '2a7b5395dd30bb1ab01ab866c06221f93f0d937c611156deffd1017a67602283'}
Processing combinations: ({'name': 'HIF-1a', 'id': 'HIF-1a'}, {'name': 'MMP', 'id': 'MMP'})
Relation trouvée: {'head': 'HIF-1a', 'tail': 'MMP', 'type': 'inhibits', 'source': '2a7b5395dd30bb1ab01ab866c06221f93f0d937c611156deffd1017a67602283'}
Processing combinations: ({'name': 'VEGF', 'id': 'VEGF'}, {'name': 'MMP', 'id': 'MMP'})
Relation trouvée: {'head': 'VEGF', 'tail': 'MMP', 'type': 'inhibits', 'source': '2a7b5395dd30bb1ab01ab866c06221f93f0d937c611156deffd1017a67602283'}
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'HIF-1', 'id': 'HIF-1'})
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'exosomes', 'id': 'exosomes'})
Relation trouvée: {'head': 'SDF-1', 'tail': 'exosomes', 'type': 'treats', 'source': '96d81bc3e3ff4a977138171b6f55bc9b8d02f1431b8dfd7a6b66bba66129309d'}
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Relation trouvée: {'head': 'SDF-1', 'tail': 'ADSCs', 'type': 'inhibits', 'source': '96d81bc3e3ff4a977138171b6f55bc9b8d02f1431b8dfd7a6b66bba66129309d'}
Processing combinations: ({'name': 'SDF-1', 'id': 'SDF-1'}, {'name': 'miR-21', 'id': 'miR-21'})
Relation trouvée: {'head': 'SDF-1', 'tail': 'miR-21', 'type': 'inhibits', 'source': '96d81bc3e3ff4a977138171b6f55bc9b8d02f1431b8dfd7a6b66bba66129309d'}
Processing combinations: ({'name': 'HIF-1', 'id': 'HIF-1'}, {'name': 'exosomes', 'id': 'exosomes'})
Relation trouvée: {'head': 'HIF-1', 'tail': 'exosomes', 'type': 'treats', 'source': '96d81bc3e3ff4a977138171b6f55bc9b8d02f1431b8dfd7a6b66bba66129309d'}
Processing combinations: ({'name': 'HIF-1', 'id': 'HIF-1'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Relation trouvée: {'head': 'HIF-1', 'tail': 'ADSCs', 'type': 'inhibits', 'source': '96d81bc3e3ff4a977138171b6f55bc9b8d02f1431b8dfd7a6b66bba66129309d'}
Processing combinations: ({'name': 'HIF-1', 'id': 'HIF-1'}, {'name': 'miR-21', 'id': 'miR-21'})
Relation trouvée: {'head': 'HIF-1', 'tail': 'miR-21', 'type': 'inhibits', 'source': '96d81bc3e3ff4a977138171b6f55bc9b8d02f1431b8dfd7a6b66bba66129309d'}
Processing combinations: ({'name': 'exosomes', 'id': 'exosomes'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Relation trouvée: {'head': 'exosomes', 'tail': 'ADSCs', 'type': 'treats', 'source': '96d81bc3e3ff4a977138171b6f55bc9b8d02f1431b8dfd7a6b66bba66129309d'}
Processing combinations: ({'name': 'exosomes', 'id': 'exosomes'}, {'name': 'miR-21', 'id': 'miR-21'})
Relation trouvée: {'head': 'exosomes', 'tail': 'miR-21', 'type': 'inhibits', 'source': '96d81bc3e3ff4a977138171b6f55bc9b8d02f1431b8dfd7a6b66bba66129309d'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'miR-21', 'id': 'miR-21'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'miR-21', 'type': 'inhibits', 'source': '96d81bc3e3ff4a977138171b6f55bc9b8d02f1431b8dfd7a6b66bba66129309d'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'burn wounds', 'id': 'burn wounds'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'burn wounds', 'type': 'associated', 'source': 'cdedc73488a406e723198399689b7908f32d1636d44f7bff08ff8fd8d8b08550'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'VEGF', 'id': 'VEGF'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'VEGF', 'type': 'inhibits', 'source': 'cdedc73488a406e723198399689b7908f32d1636d44f7bff08ff8fd8d8b08550'}
Processing combinations: ({'name': 'burn wounds', 'id': 'burn wounds'}, {'name': 'VEGF', 'id': 'VEGF'})
Relation trouvée: {'head': 'burn wounds', 'tail': 'VEGF', 'type': 'associated', 'source': 'cdedc73488a406e723198399689b7908f32d1636d44f7bff08ff8fd8d8b08550'}
Processing combinations: ({'name': 'chronic radiation wounds', 'id': 'chronic radiation wounds'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Relation trouvée: {'head': 'chronic radiation wounds', 'tail': 'ADSCs', 'type': 'causes', 'source': '2fa774a3622fa52446d1250d522d9de963244315ba867b888e17b4f5ca0d0a63'}
Processing combinations: ({'name': 'chronic radiation wounds', 'id': 'chronic radiation wounds'}, {'name': 'DF', 'id': 'DF'})
Relation trouvée: {'head': 'chronic radiation wounds', 'tail': 'DF', 'type': 'inhibits', 'source': '2fa774a3622fa52446d1250d522d9de963244315ba867b888e17b4f5ca0d0a63'}
Processing combinations: ({'name': 'chronic radiation wounds', 'id': 'chronic radiation wounds'}, {'name': 'VEGF', 'id': 'VEGF'})
Relation trouvée: {'head': 'chronic radiation wounds', 'tail': 'VEGF', 'type': 'inhibits', 'source': '2fa774a3622fa52446d1250d522d9de963244315ba867b888e17b4f5ca0d0a63'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'DF', 'id': 'DF'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'DF', 'type': 'causes', 'source': '2fa774a3622fa52446d1250d522d9de963244315ba867b888e17b4f5ca0d0a63'}
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'VEGF', 'id': 'VEGF'})
Relation trouvée: {'head': 'ADSCs', 'tail': 'VEGF', 'type': 'inhibits', 'source': '2fa774a3622fa52446d1250d522d9de963244315ba867b888e17b4f5ca0d0a63'}
Processing combinations: ({'name': 'DF', 'id': 'DF'}, {'name': 'VEGF', 'id': 'VEGF'})
Relation trouvée: {'head': 'DF', 'tail': 'VEGF', 'type': 'inhibits', 'source': '2fa774a3622fa52446d1250d522d9de963244315ba867b888e17b4f5ca0d0a63'}
Processing combinations: ({'name': 'granulocytes', 'id': 'granulocytes'}, {'name': 'HIS48*', 'id': 'HIS48*'})
Erreur: The entity "HIS48*" is not in the text.
Processing combinations: ({'name': 'granulocytes', 'id': 'granulocytes'}, {'name': '/', 'id': '/'})
Erreur: The entity "/" is not in the text.
Processing combinations: ({'name': 'granulocytes', 'id': 'granulocytes'}, {'name': 'macrophages', 'id': 'macrophages'})
Erreur: The entity "macrophages" is not in the text.
Processing combinations: ({'name': 'granulocytes', 'id': 'granulocytes'}, {'name': 'CD11b', 'id': 'CD11b'})
Erreur: The entity "CD11b" is not in the text.
Processing combinations: ({'name': 'granulocytes', 'id': 'granulocytes'}, {'name': 'CD68', 'id': 'CD68'})
Erreur: The entity "CD68" is not in the text.
Processing combinations: ({'name': 'HIS48*', 'id': 'HIS48*'}, {'name': '/', 'id': '/'})
Erreur: The entity "HIS48*" is not in the text.
Processing combinations: ({'name': 'HIS48*', 'id': 'HIS48*'}, {'name': 'macrophages', 'id': 'macrophages'})
Erreur: The entity "HIS48*" is not in the text.
Processing combinations: ({'name': 'HIS48*', 'id': 'HIS48*'}, {'name': 'CD11b', 'id': 'CD11b'})
Erreur: The entity "HIS48*" is not in the text.
Processing combinations: ({'name': 'HIS48*', 'id': 'HIS48*'}, {'name': 'CD68', 'id': 'CD68'})
Erreur: The entity "HIS48*" is not in the text.
Processing combinations: ({'name': '/', 'id': '/'}, {'name': 'macrophages', 'id': 'macrophages'})
Erreur: The entity "/" is not in the text.
Processing combinations: ({'name': '/', 'id': '/'}, {'name': 'CD11b', 'id': 'CD11b'})
Erreur: The entity "/" is not in the text.
Processing combinations: ({'name': '/', 'id': '/'}, {'name': 'CD68', 'id': 'CD68'})
Erreur: The entity "/" is not in the text.
Processing combinations: ({'name': 'macrophages', 'id': 'macrophages'}, {'name': 'CD11b', 'id': 'CD11b'})
Erreur: The entity "macrophages" is not in the text.
Processing combinations: ({'name': 'macrophages', 'id': 'macrophages'}, {'name': 'CD68', 'id': 'CD68'})
Erreur: The entity "macrophages" is not in the text.
Processing combinations: ({'name': 'CD11b', 'id': 'CD11b'}, {'name': 'CD68', 'id': 'CD68'})
Erreur: The entity "CD11b" is not in the text.
Processing combinations: ({'name': 'endothelial progenitors', 'id': 'endothelial progenitors'}, {'name': 'ADSCs', 'id': 'ADSCs'})
Processing combinations: ({'name': 'endothelial progenitors', 'id': 'endothelial progenitors'}, {'name': 'human', 'id': 'human'})
Processing combinations: ({'name': 'endothelial progenitors', 'id': 'endothelial progenitors'}, {'name': 'collagen type I', 'id': 'collagen type I'})
Erreur: The entity "collagen type I" is not in the text.
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'human', 'id': 'human'})
Processing combinations: ({'name': 'ADSCs', 'id': 'ADSCs'}, {'name': 'collagen type I', 'id': 'collagen type I'})
Erreur: The entity "collagen type I" is not in the text.
Processing combinations: ({'name': 'human', 'id': 'human'}, {'name': 'collagen type I', 'id': 'collagen type I'})
Erreur: The entity "collagen type I" is not in the text.
Nombre de relations extraites : 241

autoimmune diseases_PDF2.jpg

In [15]:
# =========================================
# Etape 10 : Insertion des relations
# =========================================

neo4j_query("""
UNWIND $data as row
MATCH (source:Entity {id: row.head})
MATCH (target:Entity {id: row.tail})
MATCH (text:Sentence {id: row.source})
MERGE (source)-[:REL]->(r:Relation {type: row.type})-[:REL]->(target)
MERGE (text)-[:MENTIONS]->(r)
""", {'data': predicted_rels})

print("Relations importées avec succès.")
Relations importées avec succès.
In [14]:
# =========================================
# Etape 11 : Enrichissement des entités
# =========================================

from SPARQLWrapper import SPARQLWrapper, JSON

def query_wikidata(entity_name):
    """
    Rechercher l'entité sur Wikidata et obtenir son QID.
    """
    sparql = SPARQLWrapper("https://query.wikidata.org/sparql")
    query = """
    SELECT ?item ?itemLabel WHERE {
      ?item ?label "%s"@en.
      SERVICE wikibase:label { bd:serviceParam wikibase:language "en". }
    }
    LIMIT 1
    """ % entity_name.replace('"', '\\"')
    sparql.setQuery(query)
    sparql.setReturnFormat(JSON)
    results = sparql.query().convert()

    if results["results"]["bindings"]:
        item = results["results"]["bindings"][0]["item"]["value"]
        itemLabel = results["results"]["bindings"][0]["itemLabel"]["value"]
        return {'wikidata_id': item.split('/')[-1], 'label': itemLabel}
    else:
        return None

# Exemple d'utilisation
entity_name = "autoimmune diseases"
result = query_wikidata(entity_name)
print(result)
{'wikidata_id': 'Q8084905', 'label': 'autoimmune disease'}
In [11]:
# =========================================
# Etape 12 : Enrichissement des entités
# =========================================

entities = neo4j_query("""
MATCH (e:Entity)
RETURN e.id AS id, e.name AS name
""")

# Enrichir chaque entité avec Wikidata
for index, row in entities.iterrows():
    wikidata_info = query_wikidata(row['name'])
    if wikidata_info:
        neo4j_query("""
        MATCH (e:Entity {id: $id})
        SET e.wikidata_id = $wikidata_id,
            e.wikidata_label = $label
        """, {'id': row['id'], 'wikidata_id': wikidata_info['wikidata_id'], 'label': wikidata_info['label']})
        print(f"Entité {row['name']} enrichie avec Wikidata ID {wikidata_info['wikidata_id']}")
    else:
        print(f"Aucune correspondance Wikidata trouvée pour l'entité {row['name']}")
Entité people enrichie avec Wikidata ID Q109205190-266291D8-366A-4755-AA3E-136C7A71C936
Entité skin diseases enrichie avec Wikidata ID Q949302
Aucune correspondance Wikidata trouvée pour l'entité chronic wounds
Aucune correspondance Wikidata trouvée pour l'entité non-healing and diabetic ulcers
Entité pluripotent enrichie avec Wikidata ID L618823
Entité pluripotent stem cells enrichie avec Wikidata ID Q15952110
Aucune correspondance Wikidata trouvée pour l'entité bone marrow stem cells
Aucune correspondance Wikidata trouvée pour l'entité fat-derived stem cells
Entité stem cells enrichie avec Wikidata ID Q48196
Aucune correspondance Wikidata trouvée pour l'entité hematopoietic stem cells
Entité leukemia enrichie avec Wikidata ID L37066
Entité autoimmune diseases enrichie avec Wikidata ID Q8084905
Entité stem cell enrichie avec Wikidata ID Q48196
Entité joint diseases enrichie avec Wikidata ID Q708176
Entité human enrichie avec Wikidata ID Q87348881
Entité Mesenchymal stem cells enrichie avec Wikidata ID Q29619804-552D66E1-1D04-470C-AF2C-7FD5E4E13F2C
Entité targeted enrichie avec Wikidata ID L5718-F3
Aucune correspondance Wikidata trouvée pour l'entité targeted tissue
Entité mesenchymal stem cells enrichie avec Wikidata ID Q1922379
Aucune correspondance Wikidata trouvée pour l'entité mesenchymal cells
Entité collagen enrichie avec Wikidata ID L30710
Entité fibroblasts enrichie avec Wikidata ID L82654-F2
Aucune correspondance Wikidata trouvée pour l'entité collagenase enzymes
Aucune correspondance Wikidata trouvée pour l'entité engineered stem cell
Entité SVF enrichie avec Wikidata ID Q113942012-09E9C0E7-3C8A-4D31-8AD4-C87796A33857
Aucune correspondance Wikidata trouvée pour l'entité inflammatory cells
Entité macrophage enrichie avec Wikidata ID L745833-S1
Aucune correspondance Wikidata trouvée pour l'entité -monocyte
Entité stem enrichie avec Wikidata ID Q109024395-D796AF63-6B88-4741-BF1F-5C616348310B
Aucune correspondance Wikidata trouvée pour l'entité CD44 receptors
Entité green enrichie avec Wikidata ID Q109022582-CA942DB7-4F88-429D-BE3B-CD90E16F84E6
Entité mice enrichie avec Wikidata ID Q109123157-5947E538-6CFF-4708-A1B7-8CEE9BF82937
Entité mouse enrichie avec Wikidata ID Q109118407-ABD19AFB-92D0-43B4-8D40-49F686AD9C60
Aucune correspondance Wikidata trouvée pour l'entité skin cells
Aucune correspondance Wikidata trouvée pour l'entité skin wounds
Entité burns enrichie avec Wikidata ID L14711-F2
Aucune correspondance Wikidata trouvée pour l'entité acute and chronic wounds
Entité Hypopigmentation enrichie avec Wikidata ID Hypopigmentation
Entité scarring enrichie avec Wikidata ID L12146-F4
Entité burn enrichie avec Wikidata ID Q109075000-C1250E4C-D6EA-4017-A9ED-3B5A2951AFA6
Aucune correspondance Wikidata trouvée pour l'entité Autologous
Aucune correspondance Wikidata trouvée pour l'entité Autologous cells
Entité allogeneic cells enrichie avec Wikidata ID Q113988031
Aucune correspondance Wikidata trouvée pour l'entité allogeneic fibroblast
Entité cells enrichie avec Wikidata ID L3911-F2
Aucune correspondance Wikidata trouvée pour l'entité hair follicle cells
Entité ADSCs enrichie avec Wikidata ID Q66082198-1251857B-3EFD-4745-BA97-6BD2EF742B5E
Aucune correspondance Wikidata trouvée pour l'entité adipose tissue-related stem cells
Entité aging enrichie avec Wikidata ID L295400
Aucune correspondance Wikidata trouvée pour l'entité dead cells
Aucune correspondance Wikidata trouvée pour l'entité CD44 fibroblast receptors
Aucune correspondance Wikidata trouvée pour l'entité dermal fibroblasts
Entité DF enrichie avec Wikidata ID DF
Entité endothelial cells enrichie avec Wikidata ID Q11394395
Entité keratinocytes enrichie avec Wikidata ID L227266-F2
Entité Adipose enrichie avec Wikidata ID Q95000281-0268728B-E5CE-447D-B141-7BEE621435F8
Entité Adipose-derived stem cells enrichie avec Wikidata ID Q84957361-D2D04B40-B825-4493-8B98-F5D8D678903A
Entité epithelial cells enrichie avec Wikidata ID Q15176415
Entité ADSC enrichie avec Wikidata ID Q30270827
Aucune correspondance Wikidata trouvée pour l'entité DFs
Entité Extracellular vesicles enrichie avec Wikidata ID Q58039410-226336E6-177A-4E68-8505-BFB016EDB78F
Entité mRNAs enrichie avec Wikidata ID L227470-F2
Aucune correspondance Wikidata trouvée pour l'entité miRNAs
Aucune correspondance Wikidata trouvée pour l'entité EVs
Entité Exosomes enrichie avec Wikidata ID Q33348053-8B12620F-4367-4C43-A517-321A463437DA
Entité extracellular vesicles enrichie avec Wikidata ID Q903634
Entité EV enrichie avec Wikidata ID Q66070629-B13456AA-103C-41BD-8DF4-628040A5F06A
Aucune correspondance Wikidata trouvée pour l'entité recipient cells
Entité MSCs enrichie avec Wikidata ID Q65465412-398161E2-ACA0-4BB8-B812-D406A0101734
Aucune correspondance Wikidata trouvée pour l'entité multipotent mesenchymal stem cells
Entité mesenchymal cell enrichie avec Wikidata ID Q66568500
Aucune correspondance Wikidata trouvée pour l'entité mesenchymal vascular fraction
Aucune correspondance Wikidata trouvée pour l'entité vesicular generating cells
Entité wound enrichie avec Wikidata ID Q109004032-7A4BA31D-5134-474B-9B79-BB58E0C23A82
Entité Epidermolysis bullosa enrichie avec Wikidata ID Q67461744-3924EE17-0A7E-4C8E-A61A-481ACC1C49EF
Entité genodermatosis enrichie avec Wikidata ID Q666075
Aucune correspondance Wikidata trouvée pour l'entité hereditary skin disease
Entité genes enrichie avec Wikidata ID L436-F1
Aucune correspondance Wikidata trouvée pour l'entité skin blistering
Entité epidermolysis bullosa enrichie avec Wikidata ID Q923020
Entité patient enrichie avec Wikidata ID Q108958165-8E7040FB-87C5-4452-B667-CB004EB8EF21
Aucune correspondance Wikidata trouvée pour l'entité renewable community
Entité patients enrichie avec Wikidata ID L5437-F2
Entité epidermolysis enrichie avec Wikidata ID L32913
Entité skin disease enrichie avec Wikidata ID L36228-S1
Aucune correspondance Wikidata trouvée pour l'entité diabetic foot ulcers
Entité DFU enrichie avec Wikidata ID DFU
Entité mesenchymal enrichie avec Wikidata ID L253982
Entité mesenchymal stem cell enrichie avec Wikidata ID Q1922379
Entité damaged enrichie avec Wikidata ID L4565-F3
Entité healthy tissue enrichie avec Wikidata ID Q105771114
Entité elastin enrichie avec Wikidata ID L1405381
Entité cell populations enrichie avec Wikidata ID Q20088819
Entité Polycaprolactone enrichie avec Wikidata ID Polycaprolactone
Entité PCL enrichie avec Wikidata ID PCL
Entité polyglycolic acid enrichie avec Wikidata ID Q424434
Entité PGA enrichie avec Wikidata ID Q2823693-CC09646F-DA0B-4FD2-A7E2-F09DBE09D37B
Entité polyhydroxyalkanoate enrichie avec Wikidata ID Q425079
Entité PHA enrichie avec Wikidata ID Q62073210-2ea08ff1-4d03-67bd-5050-b71ae489f35a
Entité polylactic acid enrichie avec Wikidata ID Q413769
Entité PLA enrichie avec Wikidata ID Q413769-93fc72f1-4d86-1fb3-4bf8-4b5c770edc2f
Entité MSC enrichie avec Wikidata ID Q349450-42a88037-4453-185a-77e8-ea65e83cac06
Entité collagen peptide enrichie avec Wikidata ID Q1779264
Entité fibrin enrichie avec Wikidata ID L296439
Aucune correspondance Wikidata trouvée pour l'entité soft tissue cell types
Aucune correspondance Wikidata trouvée pour l'entité skin disorders
Aucune correspondance Wikidata trouvée pour l'entité non-healing ulcers
Aucune correspondance Wikidata trouvée pour l'entité diabetic ulcers
Entité engineered enrichie avec Wikidata ID L32552-F3
Aucune correspondance Wikidata trouvée pour l'entité stem cell vascular fraction
Aucune correspondance Wikidata trouvée pour l'entité skin'
Aucune correspondance Wikidata trouvée pour l'entité mesenchymal/stromal stem cells
Aucune correspondance Wikidata trouvée pour l'entité stromal vascular fraction
Aucune correspondance Wikidata trouvée pour l'entité adipose derived stem cells
Aucune correspondance Wikidata trouvée pour l'entité ASCs
Entité T cells enrichie avec Wikidata ID L296336-F4
Aucune correspondance Wikidata trouvée pour l'entité adipogenic lineage
Aucune correspondance Wikidata trouvée pour l'entité bone marrow (BM)- and umbilical cord (UC)-MSCs
Entité exosomes enrichie avec Wikidata ID Q87076260-7F1C4549-21FA-4BBB-975D-B18078DE23C0
Aucune correspondance Wikidata trouvée pour l'entité younger cells
Entité melanocytes enrichie avec Wikidata ID L1331315-F2
Aucune correspondance Wikidata trouvée pour l'entité senescent cells
Aucune correspondance Wikidata trouvée pour l'entité Senescent cells
Entité wrinkles enrichie avec Wikidata ID L269679-F2
Entité oxygen enrichie avec Wikidata ID Q5203615-4d3d9b3f-432f-e8e9-9797-bc156d3b559f
Entité TGF-B enrichie avec Wikidata ID Q29734155
Entité GDF11 enrichie avec Wikidata ID GDF11
Entité GDF15 enrichie avec Wikidata ID GDF15
Aucune correspondance Wikidata trouvée pour l'entité b-FGF
Entité VEGF enrichie avec Wikidata ID Q113916670-4AB8CE56-9F74-4EAC-90B8-4174C26D9AC5
Entité MMP-1 enrichie avec Wikidata ID Q21173504
Entité MMP-2 enrichie avec Wikidata ID Q4216080
Entité MMP-9 enrichie avec Wikidata ID Q18029196
Aucune correspondance Wikidata trouvée pour l'entité aging-associated diseases
Aucune correspondance Wikidata trouvée pour l'entité epidermal atrophy
Aucune correspondance Wikidata trouvée pour l'entité pigmentation defects
Entité Langerhans cells enrichie avec Wikidata ID Q39549913-2F6FE6EC-0187-4A7F-AE25-5CE3A0844F6D
Aucune correspondance Wikidata trouvée pour l'entité impairment of skin
Entité epidermal cells enrichie avec Wikidata ID Q66558711
Aucune correspondance Wikidata trouvée pour l'entité Epidermal cells
Aucune correspondance Wikidata trouvée pour l'entité collagen type I, type III
Entité Collagen enrichie avec Wikidata ID Q64817002-4EA9CB6E-6987-4450-BB37-09B485085E2C
Aucune correspondance Wikidata trouvée pour l'entité Collagen I and III
Entité matrix metalloprotease 1 enrichie avec Wikidata ID Q21173504
Entité keratinocyte enrichie avec Wikidata ID Q64662773-71A5A531-9431-40C3-93EC-C8554745A645
Entité DE enrichie avec Wikidata ID Q2499275-C03F7EF0-496E-4D27-96BB-17EC95A79D53
Aucune correspondance Wikidata trouvée pour l'entité elastin fibers
Aucune correspondance Wikidata trouvée pour l'entité dermis atrophy
Entité MMP enrichie avec Wikidata ID Q66082263-DED67E33-DF2A-4132-BF45-A250853DEB79
Aucune correspondance Wikidata trouvée pour l'entité TIMPs
Aucune correspondance Wikidata trouvée pour l'entité collagen deficiencies
Aucune correspondance Wikidata trouvée pour l'entité genetic syndromes
Entité telomeres enrichie avec Wikidata ID L254326-F2
Aucune correspondance Wikidata trouvée pour l'entité supporting cells
Entité adipocytes enrichie avec Wikidata ID L57483-F2
Aucune correspondance Wikidata trouvée pour l'entité CXCR-4 molecules
Entité macrophages enrichie avec Wikidata ID L227261-F2
Aucune correspondance Wikidata trouvée pour l'entité T, B, and dendritic cells
Aucune correspondance Wikidata trouvée pour l'entité MicroRNA(miR)-146a
Entité cancer enrichie avec Wikidata ID Q109036672-62243817-D8E8-4D7D-8183-3AD80EE7072D
Entité inflammation enrichie avec Wikidata ID Q109060947-F795A81D-5EF7-4C16-95DA-ED8258A78763
Aucune correspondance Wikidata trouvée pour l'entité TGF-8
Aucune correspondance Wikidata trouvée pour l'entité TNF-
Aucune correspondance Wikidata trouvée pour l'entité TGF-f
Aucune correspondance Wikidata trouvée pour l'entité integrin 86
Entité IL-6 enrichie avec Wikidata ID IL-6
Entité TLR2 enrichie avec Wikidata ID Q410015
Entité TLR4 enrichie avec Wikidata ID Q2335493
Aucune correspondance Wikidata trouvée pour l'entité TGF-$
Aucune correspondance Wikidata trouvée pour l'entité microvascular endothelial cells
Entité IL-8 enrichie avec Wikidata ID IL-8
Entité MCP-1 enrichie avec Wikidata ID Q66081487-1AD95989-EEA2-431F-9FAF-B9A5014B368D
Entité skin aging enrichie avec Wikidata ID Q1591378
Aucune correspondance Wikidata trouvée pour l'entité epidermal progenitors
Aucune correspondance Wikidata trouvée pour l'entité multiple cell lineages
Aucune correspondance Wikidata trouvée pour l'entité skin-related disorders
Aucune correspondance Wikidata trouvée pour l'entité Crohns disease
Entité critical limb ischemia enrichie avec Wikidata ID Q7316059
Entité platelet enrichie avec Wikidata ID L227230
Entité platelets enrichie avec Wikidata ID L227230-F2
Entité bovine enrichie avec Wikidata ID L705511-S2
Aucune correspondance Wikidata trouvée pour l'entité cell sheets
Entité 8 enrichie avec Wikidata ID Q108820859
Aucune correspondance Wikidata trouvée pour l'entité GDFII
Aucune correspondance Wikidata trouvée pour l'entité TuR2
Aucune correspondance Wikidata trouvée pour l'entité TuR4
Aucune correspondance Wikidata trouvée pour l'entité GOFAL 1L6
Entité LAB enrichie avec Wikidata ID Q6542571-8a553159-47d8-f793-480a-25db75f15037
Aucune correspondance Wikidata trouvée pour l'entité 1L-10 GpFi1
Entité CXCR-4 enrichie avec Wikidata ID Q14874283
Entité Desmin enrichie avec Wikidata ID Desmin
Entité PDGF enrichie avec Wikidata ID Q2043946
Aucune correspondance Wikidata trouvée pour l'entité IL-
Entité TNF-a enrichie avec Wikidata ID Q18255042
Aucune correspondance Wikidata trouvée pour l'entité GDFI1
Aucune correspondance Wikidata trouvée pour l'entité m nm
Entité TFG enrichie avec Wikidata ID TFG
Entité fibroblast enrichie avec Wikidata ID L82654
Entité growth differentiation factor enrichie avec Wikidata ID Q131456511
Entité transforming growth factor enrichie avec Wikidata ID Q423671
Aucune correspondance Wikidata trouvée pour l'entité platelets derived growth factor
Entité Il-1 enrichie avec Wikidata ID Q2570871
Entité interleukin-1 enrichie avec Wikidata ID Q1706141
Aucune correspondance Wikidata trouvée pour l'entité tumor necrosis factor-
Aucune correspondance Wikidata trouvée pour l'entité basic-fibroblast growth factor
Entité vascular endothelial growth factor enrichie avec Wikidata ID Q29725
Aucune correspondance Wikidata trouvée pour l'entité C motif chemokine receptor 4
Entité SDF-1 enrichie avec Wikidata ID SDF-1
Aucune correspondance Wikidata trouvée pour l'entité stromal derived factor-1
Aucune correspondance Wikidata trouvée pour l'entité TLR2, 4
Aucune correspondance Wikidata trouvée pour l'entité toll-like receptor2,4
Entité GM-CSF enrichie avec Wikidata ID Q65378934-9D80A311-8907-4427-B8FA-FF1D50F4704B
Aucune correspondance Wikidata trouvée pour l'entité granulocyte monocyte-colony stimulating factor
Entité IGF enrichie avec Wikidata ID IGF
Aucune correspondance Wikidata trouvée pour l'entité insulin growth factor
Aucune correspondance Wikidata trouvée pour l'entité MMP-1,-2,
Entité - enrichie avec Wikidata ID Q29666007
Aucune correspondance Wikidata trouvée pour l'entité matrix metalloproteinase-1, -2, -9
Aucune correspondance Wikidata trouvée pour l'entité TNF-,
Aucune correspondance Wikidata trouvée pour l'entité chronic inflammation
Aucune correspondance Wikidata trouvée pour l'entité IL-B
Aucune correspondance Wikidata trouvée pour l'entité inflammatory-aging
Entité IL-18 enrichie avec Wikidata ID Q62735471-090E3954-A60D-4971-BDD4-054F0C77A569
Entité M1 enrichie avec Wikidata ID Q47009992-2C922143-241C-4CF6-BF7F-F4101C52F5BB
Entité M2 enrichie avec Wikidata ID Q47081593-19C249EC-1E8D-4CD0-B72F-DFF64DABAD70
Entité TNF enrichie avec Wikidata ID Q73728465-4D0B4E32-B9AC-4BC7-B2BE-2561B3A6C803
Entité IL-10 enrichie avec Wikidata ID IL-10
Aucune correspondance Wikidata trouvée pour l'entité dermal cells
Entité rat enrichie avec Wikidata ID Q108991914-69E206E6-E665-4A2D-B65B-BAF21DC4CF68
Entité CD68 enrichie avec Wikidata ID CD68
Entité nitric oxide enrichie avec Wikidata ID Q207843
Entité nitric oxide synthase enrichie avec Wikidata ID Q417619
Entité iNOS enrichie avec Wikidata ID Q18252683
Entité DESS enrichie avec Wikidata ID Q915582
Aucune correspondance Wikidata trouvée pour l'entité CD206+ M2 macrophages
Entité CD206 enrichie avec Wikidata ID Q18029278
Aucune correspondance Wikidata trouvée pour l'entité M2 macrophages
Entité monocytes enrichie avec Wikidata ID L227465-F2
Aucune correspondance Wikidata trouvée pour l'entité CD11b
Aucune correspondance Wikidata trouvée pour l'entité human skin cell
Entité psoriasis enrichie avec Wikidata ID L41360
Entité basal cell carcinoma enrichie avec Wikidata ID Q809758
Entité squamous cell carcinoma enrichie avec Wikidata ID Q681817
Aucune correspondance Wikidata trouvée pour l'entité heat shock protein 47
Entité HSP47 enrichie avec Wikidata ID Q14911942
Entité CD44 enrichie avec Wikidata ID CD44
Entité N-cadherin enrichie avec Wikidata ID Q18248252
Entité HGF enrichie avec Wikidata ID HGF
Entité endothelial progenitor cells enrichie avec Wikidata ID Q1340830
Entité HIF-1 enrichie avec Wikidata ID Q18039571
Aucune correspondance Wikidata trouvée pour l'entité VEGF gene
Aucune correspondance Wikidata trouvée pour l'entité HIF-1a
Entité miR-21 enrichie avec Wikidata ID Q18058117
Aucune correspondance Wikidata trouvée pour l'entité burn wounds
Aucune correspondance Wikidata trouvée pour l'entité chronic radiation wounds
Entité granulocytes enrichie avec Wikidata ID L296028-F2
Aucune correspondance Wikidata trouvée pour l'entité HIS48*
Entité / enrichie avec Wikidata ID Q5670736-974655df-45e8-f032-1791-94a38c77f8da
Aucune correspondance Wikidata trouvée pour l'entité endothelial progenitors
Aucune correspondance Wikidata trouvée pour l'entité collagen type I
In [12]:
# =========================================
# Etape 13 : Enrichissement des entités
# =========================================

import requests

def query_snomedct(entity_name, api_key):
    """
    Rechercher l'entité sur SNOMED-CT via BioPortal et obtenir son identifiant.
    """
    url = f"http://data.bioontology.org/search?q={entity_name}&ontologies=SNOMEDCT&apikey={api_key}"
    response = requests.get(url)
    if response.status_code == 200:
        results = response.json()
        if results['collection']:
            snomedct_id = results['collection'][0]['@id']
            pref_label = results['collection'][0].get('prefLabel', '')
            return {'snomedct_id': snomedct_id, 'pref_label': pref_label}
    return None

# clé API BioPortal
api_key = os.getenv("API_KEY_BIOPORTAL")

# Exemple d'utilisation
entity_name = "autoimmune diseases"
result = query_snomedct(entity_name, api_key)
print(result)
{'snomedct_id': 'http://purl.bioontology.org/ontology/SNOMEDCT/235728001', 'pref_label': 'Autoimmune enteropathy'}
In [13]:
# =========================================
# Etape 14 : Enrichissement des entités avec SNOMED-CT
# =========================================

for index, row in entities.iterrows():
    snomedct_info = query_snomedct(row['name'], api_key)
    if snomedct_info:
        neo4j_query("""
        MATCH (e:Entity {id: $id})
        SET e.snomedct_id = $snomedct_id,
            e.snomedct_label = $pref_label
        """, {'id': row['id'], 'snomedct_id': snomedct_info['snomedct_id'], 'pref_label': snomedct_info['pref_label']})
        print(f"Entité {row['name']} enrichie avec SNOMED-CT ID {snomedct_info['snomedct_id']}")
    else:
        print(f"Aucune correspondance SNOMED-CT trouvée pour l'entité {row['name']}")
Entité people enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/284619004
Entité skin diseases enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/2081000124103
Entité chronic wounds enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/57028002
Entité non-healing and diabetic ulcers enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/237637005
Aucune correspondance SNOMED-CT trouvée pour l'entité pluripotent
Entité pluripotent stem cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/418926001
Entité bone marrow stem cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/167934009
Entité fat-derived stem cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/472858001
Entité stem cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/418926001
Entité hematopoietic stem cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/457781000124100
Entité leukemia enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/1162768007
Entité autoimmune diseases enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/235728001
Entité stem cell enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/419758009
Entité joint diseases enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/2081000124103
Entité human enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/STY/T016
Entité Mesenchymal stem cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/418124002
Entité targeted enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/785812008
Entité targeted tissue enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/785812008
Entité mesenchymal stem cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/418124002
Entité mesenchymal cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/103650007
Entité collagen enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/61472002
Entité fibroblasts enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/64812004
Entité collagenase enzymes enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/772213007
Entité engineered stem cell enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/419758009
Aucune correspondance SNOMED-CT trouvée pour l'entité SVF
Entité inflammatory cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/708039003
Entité macrophage enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/58986001
Entité -monocyte enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/55918008
Entité stem enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/419758009
Entité CD44 receptors enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/20898008
Entité green enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/371246006
Entité mice enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/65717006
Entité mouse enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/82968002
Entité skin cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/250247005
Entité skin wounds enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/57028002
Entité burns enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/183555005
Entité acute and chronic wounds enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/396337009
Entité Hypopigmentation enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/89031001
Entité scarring enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/301005000
Entité burn enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/125666000
Entité Autologous enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/255379001
Entité Autologous cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/116768003
Entité allogeneic cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/1290661007
Entité allogeneic fibroblast enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/70277000
Entité cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/250247005
Entité hair follicle cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/238741003
Aucune correspondance SNOMED-CT trouvée pour l'entité ADSCs
Entité adipose tissue-related stem cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/472858001
Entité aging enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/248280005
Entité dead cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/419099009
Entité CD44 fibroblast receptors enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/20898008
Entité dermal fibroblasts enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/64812004
Entité DF enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/113535004
Entité endothelial cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/246970006
Entité keratinocytes enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/409345003
Entité Adipose enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/55603005
Entité Adipose-derived stem cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/472858001
Entité epithelial cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/250441008
Aucune correspondance SNOMED-CT trouvée pour l'entité ADSC
Aucune correspondance SNOMED-CT trouvée pour l'entité DFs
Entité Extracellular vesicles enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/69320009
Aucune correspondance SNOMED-CT trouvée pour l'entité mRNAs
Aucune correspondance SNOMED-CT trouvée pour l'entité miRNAs
Aucune correspondance SNOMED-CT trouvée pour l'entité EVs
Aucune correspondance SNOMED-CT trouvée pour l'entité Exosomes
Entité extracellular vesicles enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/69320009
Entité EV enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/282252004
Entité recipient cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/88930008
Aucune correspondance SNOMED-CT trouvée pour l'entité MSCs
Entité multipotent mesenchymal stem cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/418124002
Entité mesenchymal cell enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/75091002
Entité mesenchymal vascular fraction enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/118560001
Entité vesicular generating cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/63727002
Entité wound enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/416462003
Entité Epidermolysis bullosa enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/61003004
Entité genodermatosis enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/239001006
Entité hereditary skin disease enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/32895009
Entité genes enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/1251597009
Entité skin blistering enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/721542002
Entité epidermolysis bullosa enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/61003004
Entité patient enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/116154003
Entité renewable community enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/133928008
Entité patients enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/367454001
Entité epidermolysis enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/85269007
Entité skin disease enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/12441000132105
Entité diabetic foot ulcers enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/280137006
Aucune correspondance SNOMED-CT trouvée pour l'entité DFU
Entité mesenchymal enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/56565002
Entité mesenchymal stem cell enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/418124002
Entité damaged enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/247503008
Entité healthy tissue enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/276400009
Entité elastin enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/1471007
Entité cell populations enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/74042001
Aucune correspondance SNOMED-CT trouvée pour l'entité Polycaprolactone
Entité PCL enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/491531000000103
Entité polyglycolic acid enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/463323001
Entité PGA enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/121847009
Aucune correspondance SNOMED-CT trouvée pour l'entité polyhydroxyalkanoate
Entité PHA enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/17705008
Entité polylactic acid enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/415132006
Entité PLA enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/86487001
Aucune correspondance SNOMED-CT trouvée pour l'entité MSC
Entité collagen peptide enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/61472002
Entité fibrin enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/113361004
Entité soft tissue cell types enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/181607009
Entité skin disorders enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/238944001
Entité non-healing ulcers enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/39755000
Entité diabetic ulcers enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/39755000
Entité engineered enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/780846007
Entité stem cell vascular fraction enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/419758009
Entité skin' enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/19835001
Entité mesenchymal/stromal stem cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/418124002
Entité stromal vascular fraction enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/118560001
Entité adipose derived stem cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/472858001
Aucune correspondance SNOMED-CT trouvée pour l'entité ASCs
Entité T cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/104373001
Entité adipogenic lineage enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/721308005
Entité bone marrow (BM)- and umbilical cord (UC)-MSCs enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/90009001
Aucune correspondance SNOMED-CT trouvée pour l'entité exosomes
Entité younger cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/74489007
Aucune correspondance SNOMED-CT trouvée pour l'entité melanocytes
Entité senescent cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/250247005
Entité Senescent cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/250247005
Entité wrinkles enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/416175008
Entité oxygen enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/24099007
Entité TGF-B enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/28665001
Aucune correspondance SNOMED-CT trouvée pour l'entité GDF11
Aucune correspondance SNOMED-CT trouvée pour l'entité GDF15
Entité b-FGF enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/421151005
Entité VEGF enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/786911005
Entité MMP-1 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/44581004
Entité MMP-2 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/61994004
Entité MMP-9 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/1222852005
Entité aging-associated diseases enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/248280005
Entité epidermal atrophy enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/13331008
Entité pigmentation defects enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/1230005002
Entité Langerhans cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/76322003
Entité impairment of skin enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/40226000
Entité epidermal cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/724850003
Entité Epidermal cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/724850003
Entité collagen type I, type III enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/57090003
Entité Collagen enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/61472002
Entité Collagen I and III enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/57090003
Entité matrix metalloprotease 1 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/733002003
Entité keratinocyte enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/74447004
Entité DE enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/261758005
Entité elastin fibers enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/1471007
Entité dermis atrophy enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/53534000
Aucune correspondance SNOMED-CT trouvée pour l'entité MMP
Aucune correspondance SNOMED-CT trouvée pour l'entité TIMPs
Entité collagen deficiencies enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/237993009
Entité genetic syndromes enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/213015009
Aucune correspondance SNOMED-CT trouvée pour l'entité telomeres
Entité supporting cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/360135009
Aucune correspondance SNOMED-CT trouvée pour l'entité adipocytes
Entité CXCR-4 molecules enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/130898003
Entité macrophages enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/719756000
Entité T, B, and dendritic cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/104373001
Entité MicroRNA(miR)-146a enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/118364009
Entité cancer enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/363346000
Entité inflammation enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/257552002
Entité TGF-8 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/28665001
Entité TNF- enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/45244006
Entité TGF-f enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/28665001
Entité integrin 86 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/16586003
Entité IL-6 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/22766004
Aucune correspondance SNOMED-CT trouvée pour l'entité TLR2
Aucune correspondance SNOMED-CT trouvée pour l'entité TLR4
Entité TGF-$ enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/28665001
Entité microvascular endothelial cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/263809005
Entité IL-8 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/47591004
Entité MCP-1 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/4436008
Entité skin aging enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/26065007
Entité epidermal progenitors enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/724850003
Entité multiple cell lineages enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/403905005
Entité skin-related disorders enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/201433006
Entité Crohns disease enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/112561000119108
Entité critical limb ischemia enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/233960004
Entité platelet enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/16378004
Entité platelets enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/277200003
Entité bovine enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/389115008
Entité cell sheets enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/255292000
Entité 8 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/130258006
Aucune correspondance SNOMED-CT trouvée pour l'entité GDFII
Aucune correspondance SNOMED-CT trouvée pour l'entité TuR2
Aucune correspondance SNOMED-CT trouvée pour l'entité TuR4
Aucune correspondance SNOMED-CT trouvée pour l'entité GOFAL 1L6
Entité LAB enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/410394004
Entité 1L-10 GpFi1 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/14306003
Entité CXCR-4 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/130898003
Entité Desmin enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/83475004
Aucune correspondance SNOMED-CT trouvée pour l'entité PDGF
Entité IL- enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/1559004
Entité TNF-a enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/45244006
Aucune correspondance SNOMED-CT trouvée pour l'entité GDFI1
Entité m nm enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/258675004
Entité TFG enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/1187566006
Entité fibroblast enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/52547004
Entité growth differentiation factor enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/81286007
Entité transforming growth factor enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/708710005
Entité platelets derived growth factor enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/10987005
Entité Il-1 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/25383000
Entité interleukin-1 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/50762005
Entité tumor necrosis factor- enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/8612007
Entité basic-fibroblast growth factor enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/88919005
Entité vascular endothelial growth factor enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/417324009
Entité C motif chemokine receptor 4 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/725307005
Entité SDF-1 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/44581004
Entité stromal derived factor-1 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/10987005
Entité TLR2, 4 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/130898003
Entité toll-like receptor2,4 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/159513002
Entité GM-CSF enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/419800004
Entité granulocyte monocyte-colony stimulating factor enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/70077006
Entité IGF enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/237642002
Entité insulin growth factor enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/259878008
Entité MMP-1,-2, enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/303183002
Aucune correspondance SNOMED-CT trouvée pour l'entité -
Entité matrix metalloproteinase-1, -2, -9 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/707620006
Entité TNF-, enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/45244006
Entité chronic inflammation enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/39391009
Entité IL-B enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/1559004
Entité inflammatory-aging enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/248280005
Entité IL-18 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/1559004
Entité M1 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/409097003
Entité M2 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/278077005
Entité TNF enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/8612007
Entité IL-10 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/1559004
Entité dermal cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/402682003
Entité rat enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/782007
Entité CD68 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/31001006
Entité nitric oxide enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/6710000
Entité nitric oxide synthase enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/130168007
Aucune correspondance SNOMED-CT trouvée pour l'entité iNOS
Aucune correspondance SNOMED-CT trouvée pour l'entité DESS
Entité CD206+ M2 macrophages enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/719756000
Aucune correspondance SNOMED-CT trouvée pour l'entité CD206
Entité M2 macrophages enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/719756000
Entité monocytes enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/165540007
Entité CD11b enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/407715006
Entité human skin cell enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/314819008
Entité psoriasis enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/9014002
Entité basal cell carcinoma enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/1338007
Entité squamous cell carcinoma enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/1162767002
Entité heat shock protein 47 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/115571001
Aucune correspondance SNOMED-CT trouvée pour l'entité HSP47
Entité CD44 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/20898008
Entité N-cadherin enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/256133008
Entité HGF enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/30965005
Entité endothelial progenitor cells enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/711428009
Entité HIF-1 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/44581004
Entité VEGF gene enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/67271001
Entité HIF-1a enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/264653008
Entité miR-21 enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/1222866000
Entité burn wounds enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/57028002
Entité chronic radiation wounds enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/235762001
Entité granulocytes enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/426518006
Aucune correspondance SNOMED-CT trouvée pour l'entité HIS48*
Aucune correspondance SNOMED-CT trouvée pour l'entité /
Entité endothelial progenitors enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/2218006
Entité collagen type I enrichie avec SNOMED-CT ID http://purl.bioontology.org/ontology/SNOMEDCT/58520002